Reaction

Clonus reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,707 reports · 138 co-occurring drugs

As of the last recalculation, Clonus appears in 2,707 FAERS reports alongside 138 co-occurring drug terms. The strongest observed disproportionality signal is PROPOFOL (PRR 24.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Propofol	112	24.5	24.6
Paroxetine Hydrochloride Hemihydrate	93	22.2	22.3
Paroxetine	93	21.7	21.8
Dimenhydrinate	28	20.4	20.5
Lithium	58	18.1	18.1
Lithium Bromatum	58	18.1	18.1
Midazolam Hydrochloride	61	17.8	17.8
Lithium Carbonate	37	17.0	17.0
Venlafaxine	147	16.6	16.7
Escitslopram	120	16.6	16.6
Rocuronium Bromide	25	16.5	16.5
Sumatriptan Succinate	51	15.8	15.8
Midazolam	50	15.5	15.5
Haloperidol Lactate	49	15.5	15.5
Haloperidol	48	15.4	15.5
Dextrose	26	15.3	15.3
Fluoxetine	127	15.3	15.3
Dextrose Monohydrate	26	15.1	15.1
Escitalopram Oxalate	135	14.9	15.0
Baclofen	156	14.7	14.7
Oxybutynin Chloride	16	14.1	14.1
Lamotirigine	125	14.0	14.0
Lamotrigine Extended-Release	125	14.0	14.0
Lamotrigine Chewable Dispersible	125	14.0	14.0
Bupropion	77	13.6	13.7
Magnesium Sulfate In Water For	21	12.7	12.8
Magnesium Sulfate Heptahydrate	21	12.5	12.5
Magnesium Sulfate	21	12.5	12.5
Duloxetine	102	11.7	11.7
Prochlorperazine	41	11.5	11.5
Paroxetine Hydrochloride	128	11.3	11.3
Tranexamic Acid	13	11.3	11.3
Sevoflurane	12	11.1	11.2
Fentanyl	134	11.0	11.0
Felodipine Extended-Release Tablets	16	10.9	10.9
Felodipine	16	10.9	10.9
Fosaprepitant Dimeglumine	19	10.7	10.7
Oxazepam	29	10.5	10.5
Fluoxetine Hydrochloride	163	10.4	10.4
Venlafaxine Hydrochloride	164	10.1	10.1
Polyethylene Glycol	14	10.0	10.0
Linezolid	38	9.9	10.0
Quetiapine Fumarate	37	9.8	9.8
Phenytoin	26	9.7	9.7
Sumatriptan	47	9.6	9.6
Sodium Bicarbonate	28	9.3	9.4
Sodium Bicarbonate Injection,	28	9.3	9.4
Lamotrigine	148	9.1	9.1
Ondansetron Hydrochloride	134	8.8	8.8
Sertraline	126	8.6	8.6
Citalopram Hydrobromide	114	8.5	8.5
Aripiprazole Oral	45	8.5	8.5
Aripiprazole Orally Disintegrating	45	8.5	8.5
Ondansetron	116	8.5	8.5
Ondansetron Tablets	116	8.5	8.5
Amphetamine	9	8.4	8.4
Escitalopram	145	8.3	8.3
Valproic Acid	33	8.1	8.1
Hydroxyzine	49	8.0	8.0
Quetiapine	188	8.0	8.0
Metoclopramide	56	8.0	8.0
Valproate Sodium	21	7.9	7.9
Atropine	8	7.4	7.4
Diazepam Oral Solution (Concentrate)	83	7.4	7.4
Diazepam Oral	83	7.4	7.4
Dalteparin Sodium	10	7.3	7.3
Citalopram	124	7.3	7.3
Norepinephrine	10	7.2	7.2
Atropine Sulfate	10	7.1	7.1
Metoclopramide Hydrochloride	70	7.1	7.1
Morphine	67	7.1	7.1
Buspirone Hydrochloride	10	7.0	7.0
Diazepam	106	6.9	6.9
Ganciclovir	9	6.8	6.8
Piperacillin Sodium,Tazobactam Sodium	23	6.7	6.7
Piperacillin And Tazobactam	11	6.6	6.6
Ganciclovir Sodium	9	6.6	6.6
Cyclobenzaprine	41	6.4	6.4
Phenobarbital	12	6.4	6.4
Olanzapine	86	6.3	6.3
Aprepitant	15	6.3	6.3
Cefepime Hydrochloride	13	6.2	6.2
Bupropion Hydrochloride	78	6.2	6.2
Rivastigmine	15	6.2	6.2
Lacosamide	29	6.0	6.1
Duloxetine Hydrochloride	141	6.0	6.0
Norepinephrine Bitartrate	11	5.9	5.9
Methimazole	6	5.9	5.9
Mirtazapine	68	5.8	5.8
Meropenem	24	5.8	5.8
Diphenhydramine	46	5.7	5.7
Memantine	10	5.6	5.6
Memantine Hydrochloride	10	5.6	5.6
Abacavir Sulfate	7	5.5	5.5
Piperacillin Sodium And Tazobactam Sodium	14	5.5	5.5
Asenapine Maleate	6	5.3	5.3
Primidone	7	5.3	5.3
Sotalol Hydrochloride	11	5.1	5.1
Levetiracetam In Sodium Chloride	50	5.0	5.0
Levetiracetam Oral	50	5.0	5.0
Levetiracetam Injection	50	5.0	5.0
Levetiracetam	85	5.0	5.0
Doxazosin	18	5.0	5.0
Bupivacaine	6	4.9	4.9
Quinapril Hydrochloride	5	4.9	4.9
Tizanidine	15	4.9	4.9
Ziprasidone	11	4.8	4.8
Melphalan	14	4.8	4.8
Clobazam	15	4.7	4.7
Melphalan Hydrochloride	15	4.6	4.6
Ethyl Alcohol	16	4.5	4.6
Methadone	25	4.5	4.5
Tramadol Hydrochloride	22	4.5	4.5
Levodopa	7	4.5	4.5
Cefepime	8	4.3	4.3
Daptomycin	5	4.2	4.2
Isopropyl Alcohol	17	3.9	3.9
Fentanyl Citrate	9	3.9	3.9
Tobramycin Solution	6	3.8	3.8
Fondaparinux Sodium	4	3.8	3.8
Posaconazole	8	3.8	3.8
Atazanavir	7	3.8	3.8
Vigabatrin	7	3.7	3.7
Alcohol	18	3.6	3.6
Methadone Hydrochloride	5	3.6	3.6
Pseudoephedrine Hcl	5	3.5	3.5
Tapentadol Hydrochloride	15	3.5	3.5
Dalfampridine	32	3.5	3.5
Desvenlafaxine Succinate	12	3.4	3.4
Alteplase	6	3.1	3.1
Pseudoephedrine Hydrochloride	4	3.0	3.0
Rifaximin	8	2.9	2.9
Oseltamivir	3	2.9	2.9
Pemetrexed Disodium	14	2.8	2.8
Iohexol	3	2.8	2.8
Vortioxetine	6	2.7	2.7
Lurasidone Hydrochloride	7	2.6	2.6
Brexpiprazole	4	1.9	1.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.