Reaction

Product Ineffective For Unapproved Use reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,380 reports · 122 co-occurring drugs

As of the last recalculation, Product Ineffective For Unapproved Use appears in 1,380 FAERS reports alongside 122 co-occurring drug terms. The strongest observed disproportionality signal is OSELTAMIVIR (PRR 58.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Oseltamivir	30	58.1	58.3
Botulinum Toxin Type A	41	51.3	51.5
Rizatriptan Benzoate	33	50.1	50.3
Trimethoprim	32	41.9	42.0
Indomethacin	33	38.5	38.6
Mometasone	40	33.8	33.9
Human Immunoglobulin G	39	29.3	29.4
Ganciclovir Sodium	19	27.4	27.5
Dexamethasone Sodium Phosphate	18	27.1	27.1
Ganciclovir	17	25.4	25.4
Drs. Clotrimazole	19	25.1	25.2
Family Wellness Clotrimazole	19	25.1	25.2
Clotrimazole Topical	19	25.1	25.2
Clotrimazole	19	23.6	23.7
Amphotericin B	19	23.2	23.2
Instalax Polyethylene Glycol 3350	18	22.2	22.2
Polyethylene Glycol 400	18	21.7	21.7
Tofacitinib Citrate	18	21.0	21.0
Rabeprazole	30	20.9	20.9
Sirolimus	18	20.4	20.4
Sumatriptan Succinate	33	20.2	20.2
Oseltamivir Phosphate	30	18.9	18.9
Norepinephrine	13	18.5	18.5
Meropenem	36	17.3	17.4
Acetaminophen And Codeine	13	16.2	16.3
Cefepime	15	15.9	16.0
Azithromycin Monohydrate	42	15.7	15.7
Mycophenolate Mofetil	128	15.6	15.6
Mycophenolate Mofetil Hydrochloride	128	15.5	15.6
Busulfan	16	15.5	15.5
Adalimumab-Fkjp	46	15.5	15.5
Brivaracetam	9	15.2	15.2
Anti-Thymocyte Globulin (Rabbit)	8	15.0	15.1
Propranolol Hydrochloride	68	14.9	14.9
Cephalexin	21	14.8	14.9
Norepinephrine Bitartrate	14	14.8	14.8
Adalimumab-Aaty	45	14.8	14.8
Phenobarbital	14	14.7	14.7
Anakinra	16	14.7	14.7
Azithromycin	38	14.6	14.6
Levetiracetam In Sodium Chloride	71	14.5	14.5
Levetiracetam Oral	71	14.5	14.5
Levetiracetam Injection	71	14.5	14.5
Clarithromycin	32	14.4	14.4
Micafungin Sodium	8	14.3	14.3
Midazolam Hydrochloride	25	14.2	14.3
Cefepime Hydrochloride	15	14.2	14.2
Lacosamide	33	13.7	13.7
Esomeprazole Magnesium Capsule, Delayed Release	13	13.6	13.6
Esomeprazole Magnesium Delayed Release Capsules	13	13.6	13.6
Esomeprazole Magnesium Dihydrate	13	13.6	13.6
Tacrolimus Ointment 0.1%	104	13.5	13.6
Tacrolimus Extended-Release Capsules	104	13.5	13.5
Midazolam	22	13.4	13.4
Adalimumab-Adaz	45	13.3	13.3
Vancomycin	48	12.9	13.0
Basiliximab	10	12.9	12.9
Acetylcysteine	8	12.9	12.9
Metronidazole Topical	39	12.7	12.7
Topiramate	74	12.6	12.6
Cyclosporine	86	12.4	12.4
Tramadol Hydrochloride	30	12.3	12.3
Mometasone Furoate	32	11.8	11.8
Vancomycin Hydrochloride	49	11.6	11.6
Valganciclovir Hydrochloride Powder,	9	11.2	11.2
Valproic Acid	23	11.2	11.2
Colchicine	19	11.0	11.0
Mesna Injection	6	11.0	11.0
Phenytoin	15	11.0	11.0
Fludarabine Phosphate	28	10.9	10.9
Tacrolimus	105	10.9	10.9
Diclofenac Potassium, Film Coated	6	10.8	10.8
Mesna	6	10.8	10.8
Diclofenac Potassium Tablets	6	10.8	10.8
Valganciclovir	13	10.5	10.5
Valganciclovir Hydrochloride	13	10.5	10.5
Hydroxyzine Hydrochloride	9	10.4	10.4
Hydroxyzine Hydrochloride Oral	9	10.4	10.4
Piperacillin Sodium,Tazobactam Sodium	18	10.4	10.4
Pseudoephedrine Hydrochloride	7	10.3	10.3
Clobetasol Propionate Ointment Usp, 0.05%	7	10.3	10.3
Mycophenilic Acid	14	10.3	10.3
Clobetasol Propionate	7	10.3	10.3
Clobazam	16	10.0	10.0
Pseudoephedrine Hcl	7	9.6	9.6
Metoclopramide	34	9.6	9.6
Voriconazole Injection	13	9.1	9.1
Triamcinolone Acetonide Ointment Usp, 0.05%	14	9.1	9.1
Ruxolitinib	41	8.9	8.9
Levetiracetam	73	8.6	8.7
Cyclophosphamide Injection, Solution	95	8.6	8.6
Cyclophosphamide	95	8.6	8.6
Cyclophosphamide For Injection	95	8.6	8.6
Diclofenac Potassium	6	8.4	8.4
Azacitidine For	10	8.3	8.3
Rifampin	8	8.3	8.3
Naproxen Sodium Tablet, Coated	7	7.8	7.8
Naproxen Sodium, Coated Tablets	7	7.8	7.8
Naproxen Sodium 220Mg	7	7.8	7.8
Bendamustine Hcl	8	7.8	7.8
Memantine	7	7.7	7.8
Memantine Hydrochloride	7	7.7	7.8
Lanreotide Acetate	4	7.7	7.7
Etoposide	32	6.7	6.7
Daptomycin	4	6.6	6.6
Rocuronium Bromide	5	6.4	6.4
Sarilumab	10	5.7	5.7
Remdesivir	5	5.7	5.7
Eculizumab	20	5.6	5.6
Selinexor	3	5.2	5.2
Azacitidine	10	5.1	5.1
Nemolizumab-Ilto	4	4.8	4.8
Polatuzumab Vedotin	3	4.6	4.6
Eltrombopag Olamine	7	4.6	4.6
Ravulizumab	4	4.5	4.5
Bimekizumab	6	4.3	4.3
Erenumab-Aooe	15	4.1	4.1
Dupilumab	118	3.9	3.9
Apalutamide	3	3.9	3.9
Valbenazine	3	1.8	1.8
Pimavanserin Tartrate	6	1.6	1.6
Adapalene	4	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.