Reaction

Endometriosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,708 reports · 131 co-occurring drugs

As of the last recalculation, Endometriosis appears in 4,708 FAERS reports alongside 131 co-occurring drug terms. The strongest observed disproportionality signal is LEUPROLIDE ACETATE (PRR 52.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Leuprolide Acetate	772	52.4	53.0
Botulinum Toxin Type A	106	38.6	38.9
Telmisartan	103	26.1	26.2
Sumatriptan Succinate	124	22.2	22.4
Etonogestrel And Ethinyl Estradiol	89	18.1	18.1
Calcium, Magnesium, Potassium, And Sodium Oxybates	29	15.0	15.0
Dexlansoprazole	118	12.8	12.8
Bupropion	113	11.5	11.5
Rosuvastatin Calcium	67	10.7	10.7
Sumatriptan	90	10.6	10.6
Mesalamine	126	10.2	10.2
Copper	90	9.4	9.4
Sodium Oxybate	129	8.9	8.9
Budesonide	108	8.3	8.3
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	65	8.2	8.3
Rizatriptan Benzoate	17	7.4	7.4
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	68	7.3	7.3
Venlafaxine	114	7.2	7.2
Levonorgestrel	292	6.8	6.8
Armodafinil	31	6.5	6.5
Progesterone	33	6.4	6.4
Hyoscyamine Sulfate	13	6.3	6.3
Modafinil	45	6.2	6.2
Drospirenone And Ethinyl Estradiol	61	6.2	6.2
Adalimumab-Fkjp	63	6.1	6.1
Fentanyl	127	5.8	5.8
Promethazine Hydrochloride	24	5.7	5.7
Venlafaxine Hydrochloride	164	5.6	5.6
Lubiprostone	12	5.6	5.6
Adalimumab-Adaz	65	5.5	5.5
Adalimumab-Aaty	58	5.5	5.5
Tretinoin	10	5.5	5.5
Estradiol Gel 0.1%	55	5.4	5.4
Estradiol Transdermal	55	5.4	5.4
Vilazodone Hydrochloride	11	5.3	5.3
Goserelin	15	5.0	5.0
Medroxyprogesterone Acetate	54	4.8	4.8
Estradiol	92	4.8	4.8
Dicyclomine Hydrochloride	15	4.7	4.7
Fremanezumab-Vfrm	12	4.6	4.6
Infliximab-Dyyb	30	4.6	4.6
Octreotide Acetate	31	4.5	4.5
Buspirone Hydrochloride	11	4.4	4.4
Infliximab	209	4.4	4.4
Multivitamin	49	4.4	4.4
Naproxen Sodium Tablet, Coated	13	4.3	4.3
Naproxen Sodium, Coated Tablets	13	4.3	4.3
Naproxen Sodium 220Mg	13	4.2	4.3
Interferon Beta-1A	178	4.2	4.2
Albuterol	111	4.2	4.2
Butalbital, Acetaminophen, And Caffeine	10	4.2	4.2
Topiramate	81	3.9	3.9
Eptinezumab-Jjmr	8	3.9	3.9
Adalimumab	566	3.9	3.9
Meperidine Hydrochloride	8	3.8	3.8
Etonogestrel	41	3.8	3.8
Oxycodone And Acetaminophen Tablets	10	3.7	3.7
Everolimus Tablets	14	3.7	3.7
Linaclotide	22	3.7	3.7
Lisdexamfetamine Dimesylate	27	3.6	3.6
Vedolizumab	70	3.6	3.6
Conjugated Estrogens	45	3.4	3.4
Ibuprofen And Diphenhydramine Citrate	18	3.4	3.4
Estrogens, Conjugated	45	3.4	3.4
Ergocalciferol	281	3.4	3.4
Raloxifene Hydrochloride	11	3.3	3.3
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	36	3.2	3.2
Ibuprofen Capsule	141	3.2	3.2
Ibuprofen Tablet, Film Coated	141	3.2	3.2
Ibupfrofen	141	3.2	3.2
Ibuprofen Tablets Usp, 200Mg	141	3.2	3.2
Ibuprofen Oral	141	3.2	3.2
Ibuprofen Capsules 200 Mg	141	3.2	3.2
Ibuprofen 200 Mg	141	3.2	3.2
Ibuprofen 200Mg	141	3.2	3.2
Tizanidine Hydrochloride	13	3.2	3.2
Methylphenidate Hydrochloride	42	3.2	3.2
Desvenlafaxine Succinate	19	3.1	3.1
Exemestane	15	3.1	3.1
Oxycodone Hydrochloride And Acetaminophen	68	3.1	3.1
Liothyronine Sodium	6	3.0	3.0
Oxybutynin Chloride	6	3.0	3.0
Cetirizine Hcl	6	2.9	2.9
Fexofenadine Hcl	6	2.9	2.9
Fesoterodine Fumarate	7	2.9	2.9
Cetirizine Hydrochloride	103	2.8	2.8
Risankizumab-Rzaa	51	2.8	2.8
Peginterferon Beta-1A	8	2.7	2.7
Fexofenadine Hydrochloride	13	2.6	2.6
Ado-Trastuzumab Emtansine	5	2.6	2.6
Epinephrine	38	2.6	2.6
Buprenorphine Hydrochloride, Naloxone Hydrochloride	14	2.6	2.6
Certolizumab Pegol	66	2.5	2.5
Elexacaftor, Tezacaftor, And Ivacaftor	7	2.5	2.5
Azelastine	10	2.5	2.5
Natalizumab	100	2.5	2.5
Eszopiclone	14	2.4	2.4
Loratadine Tablet	28	2.3	2.3
Mometasone Furoate And Formoterol Fumarate Dihydrate	8	2.3	2.3
Ivacaftor	4	2.2	2.2
Asfotase Alfa	5	2.2	2.2
Golimumab	42	2.2	2.2
Dimethyl Fumarate	58	2.1	2.1
Oxycodone And Acetaminophen	11	2.1	2.1
Omalizumab	39	2.0	2.0
Isotretinoin	22	2.0	2.0
Upadacitinib	36	2.0	2.0
Ocrelizumab	27	1.9	1.9
Methylphenidate	12	1.8	1.8
Conjugated Estrogens And Medroxyprogesterone Acetate	9	1.7	1.7
Diclofenac Potassium	4	1.6	1.6
Interferon Beta-1B	7	1.6	1.6
Pegvaliase-Pqpz	3	1.6	1.6
Ofatumumab	12	1.6	1.6
Vortioxetine	6	1.6	1.6
Voclosporin	3	1.5	1.5
Hydrocodone Bitartrate And Acetaminophen	19	1.5	1.5
Onabotulinumtoxina	26	1.5	1.5
Agalsidase Beta	3	1.4	1.4
Cariprazine	3	1.4	1.4
Rimegepant Sulfate	4	1.4	1.4
Ravulizumab	4	1.3	1.3
Galcanezumab-Gnlm	9	1.3	1.3
Glecaprevir And Pibrentasvir	3	1.2	1.2
Diroximel Fumarate	3	1.1	1.1
Glatiramer Acetate	15	1.1	1.1
Dornase Alfa	4	0.9	0.9
Bimekizumab	4	0.8	0.8
Tapentadol Hydrochloride	6	0.8	0.8
Tirzepatide	24	0.7	0.7
Droxidopa	3	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.