Reaction

Hyperphagia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,914 reports · 131 co-occurring drugs

As of the last recalculation, Hyperphagia appears in 3,914 FAERS reports alongside 131 co-occurring drug terms. The strongest observed disproportionality signal is VORTIOXETINE (PRR 54.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Vortioxetine	168	54.8	55.4
Olanzapine Pamoate	139	18.7	18.7
Brexpiprazole	50	16.2	16.3
Aripiprazole Oral	104	13.7	13.7
Aripiprazole Orally Disintegrating	104	13.7	13.7
Aripiprazole	262	12.1	12.1
Teduglutide	28	11.1	11.1
Olanzapine	213	11.1	11.1
Lithium Carbonate	33	10.4	10.4
Ziprasidone Mesylate	26	9.8	9.8
Pramipexole	27	9.4	9.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	15	9.4	9.4
Oral Semaglutide	122	9.1	9.1
Risperidone	216	9.1	9.1
Ziprasidone	29	8.8	8.8
Lurasidone Hydrochloride	34	8.7	8.7
Captopril	15	8.3	8.3
Lithium	39	8.3	8.3
Lithium Bromatum	39	8.3	8.3
Buspirone Hydrochloride	17	8.2	8.2
Guanfacine	12	8.1	8.1
Paliperidone	35	8.0	8.1
Cariprazine	14	8.0	8.0
Atomoxetine Hydrochloride	33	7.4	7.4
Varenicline Tartrate	109	7.4	7.4
Lisdexamfetamine Dimesylate	45	7.3	7.3
Rasagiline Mesylate	15	7.2	7.2
Methylphenidate Hydrochloride	74	6.8	6.8
Cetirizine Hcl	11	6.4	6.4
Divalproex Sodium	54	6.2	6.2
Orlistat	29	6.0	6.0
Carbidopa And Levodopa	52	5.9	5.9
Quetiapine	196	5.6	5.6
Oxybutynin Chloride	9	5.5	5.5
Memantine	13	5.1	5.1
Memantine Hydrochloride	13	5.1	5.1
Haloperidol	23	5.1	5.1
Haloperidol Lactate	23	5.0	5.0
Bupropion Hydrochloride	90	4.9	4.9
Tenofovir Disoproxil Fumarate Tablets	8	4.9	4.9
Valproate Sodium	19	4.9	4.9
Quetiapine Fumarate	27	4.9	4.9
Ropinirole	14	4.9	4.9
Paliperidone Palmitate	28	4.7	4.7
Darunavir	13	4.6	4.6
Lamotirigine	59	4.4	4.4
Lamotrigine Extended-Release	59	4.4	4.4
Lamotrigine Chewable Dispersible	59	4.4	4.4
Escitslopram	48	4.4	4.4
Abacavir Sulfate	8	4.4	4.4
Lamotrigine	105	4.3	4.3
Asenapine Maleate	7	4.3	4.3
Sertraline Hydrochloride	92	4.2	4.2
Eszopiclone	20	4.2	4.2
Clonazepam	120	4.1	4.1
Relugolix	18	4.1	4.1
Mirtazapine	69	4.1	4.1
Vilazodone Hydrochloride	7	4.0	4.0
Melatonin	41	4.0	4.0
Insulin Human	30	4.0	4.0
Biotin	23	3.9	3.9
Ritonavir 100 Mg	11	3.9	3.9
Escitalopram Oxalate	53	3.9	3.9
Raltegravir	12	3.9	3.9
Methylphenidate	21	3.9	3.9
Escitalopram	100	3.9	3.9
Fluoxetine Hydrochloride	91	3.9	3.9
Efavirenz	8	3.8	3.8
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	29	3.7	3.7
Suvorexant	9	3.7	3.7
Alpelisib	6	3.7	3.7
Naltrexone	21	3.6	3.6
Insulin Degludec	16	3.6	3.6
Budesonide, Glycopyrrolate, And Formoterol Fumarate	7	3.6	3.6
Azelastine	12	3.6	3.6
Desvenlafaxine Succinate	18	3.6	3.6
Nevirapine	6	3.5	3.5
Lovastatin	17	3.5	3.5
Elexacaftor, Tezacaftor, And Ivacaftor	8	3.4	3.4
Human Insulin	8	3.4	3.4
Glimepiride	24	3.3	3.3
Ritonavir	18	3.3	3.3
Raloxifene Hydrochloride	9	3.3	3.3
Sertraline	71	3.3	3.3
Zonisamide	9	3.2	3.2
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	21	3.2	3.2
Goserelin	8	3.2	3.2
Insulin Glulisine	6	3.1	3.1
Ruxolitinib	41	3.1	3.1
Valproic Acid	18	3.0	3.0
Sofosbuvir	11	3.0	3.0
Cannabidiol	13	3.0	3.0
Niraparib	12	2.9	2.9
Somatropin	37	2.7	2.7
Diroximel Fumarate	6	2.7	2.7
Sodium Oxybate	33	2.7	2.7
Levodopa	6	2.6	2.6
Tirzepatide	78	2.6	2.6
Rotigotine	7	2.6	2.6
Amphetamine	4	2.6	2.6
Dofetilide	5	2.5	2.5
Pimavanserin Tartrate	26	2.5	2.5
Icosapent Ethyl	4	2.5	2.5
Clobazam	11	2.4	2.4
Abemaciclib	9	2.4	2.4
Liraglutide	21	2.3	2.3
Nintedanib	13	2.2	2.2
Dulaglutide	36	2.2	2.2
Rimegepant Sulfate	5	2.1	2.1
Clozapine	48	2.0	2.0
Exenatide	20	2.0	2.0
Vibegron	3	2.0	2.0
Pegvaliase-Pqpz	3	1.9	1.9
Valbenazine	9	1.9	1.9
Dornase Alfa	7	1.9	1.9
Canagliflozin	10	1.8	1.8
Tenofovir Disoproxil Fumarate	11	1.8	1.8
Avapritinib	4	1.8	1.8
Abiraterone	4	1.6	1.6
Patiromer	4	1.5	1.5
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	1.5	1.5
Vigabatrin	4	1.5	1.5
Sarilumab	7	1.4	1.4
Etonogestrel	12	1.3	1.3
Sacubitril And Valsartan	26	1.2	1.2
Dimethyl Fumarate	27	1.2	1.2
Minoxidil Foam 5% (Womens)	6	1.0	1.0
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.9	0.9
Dupilumab	72	0.8	0.8
Levonorgestrel	27	0.7	0.7
Minoxidil	6	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.