Reaction

Pulmonary Function Test Decreased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,343 reports · 119 co-occurring drugs

As of the last recalculation, Pulmonary Function Test Decreased appears in 4,343 FAERS reports alongside 119 co-occurring drug terms. The strongest observed disproportionality signal is LUMACAFTOR AND IVACAFTOR (PRR 244.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Lumacaftor And Ivacaftor	397	244.2	256.1
Dornase Alfa	493	135.8	139.3
Tobramycin	425	93.8	95.4
Ciclesonide	243	90.5	92.1
Elexacaftor, Tezacaftor, And Ivacaftor	216	87.3	88.8
Ivacaftor	138	86.0	87.5
Tobramycin Solution	128	52.6	53.1
Tobramycin Sulfate	130	51.8	52.4
Pancrelipase	305	40.7	41.0
Nintedanib	212	34.0	34.2
Pirfenidone	231	28.7	28.8
Fluticasone Propionate And Salmeterol Xinafoate	291	24.8	24.9
Ipratropium Bromide	167	23.3	23.4
Budesonide And Formoterol Fumarate Dihydrate	392	21.2	21.3
Fluticasone Furoate And Vilanterol Trifenatate	141	19.4	19.5
Omalizumab	316	19.1	19.2
Theophylline	38	16.0	16.0
Tiotropium Bromide	406	15.6	15.6
Mepolizumab	155	15.5	15.5
Phytonadione	27	15.3	15.4
Theophylline Anhydrous	38	14.8	14.9
Tiotropium Bromide Inhalation Spray	34	14.6	14.7
Ursosiol	58	14.5	14.5
Montelukast Sodium	331	14.0	14.1
Amikacin	48	13.6	13.7
Azithromycin Dihydrate	157	13.3	13.3
Mometasone Furoate	110	13.0	13.0
Ursodiol	58	12.9	13.0
Albuterol Sulfate	657	12.3	12.3
Salmeterol Xinafoate	22	12.3	12.3
Albuterol	274	11.6	11.6
Azithromycin	95	11.5	11.6
Azithromycin Monohydrate	95	11.2	11.2
0Xygen	109	10.9	10.9
Oxygen	109	10.9	10.9
Sodium Chloride	171	10.8	10.8
Polyethylene Glycol	24	10.7	10.7
Benralizumab	44	10.6	10.7
Sodium Chloride Tablet	156	10.5	10.5
Sodium Chloride Tablets	156	10.5	10.5
Mometasone Furoate And Formoterol Fumarate Dihydrate	33	10.2	10.2
Umeclidinium	19	10.2	10.2
Budesonide, Glycopyrrolate, And Formoterol Fumarate	21	9.7	9.7
Montelukast	139	8.2	8.2
Rosuvastatin Calcium	47	8.1	8.1
Acetylcysteine	15	7.7	7.7
Itraconazole	17	7.0	7.0
Bleomycin Sulfate	15	7.0	7.0
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	67	6.5	6.5
Voriconazole Injection	29	6.4	6.4
Fluticasone Propionate And Salmeterol	55	6.4	6.4
Fluticasone Propionate	160	6.1	6.1
Vitamin E	37	5.7	5.7
Valganciclovir	22	5.6	5.6
Valganciclovir Hydrochloride	22	5.6	5.6
Lubiprostone	11	5.6	5.6
Prednisone	522	5.5	5.5
Budesonide	66	5.4	5.4
Risedronate Sodium	35	5.4	5.4
Fluticasone Furoate	13	5.2	5.2
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	44	5.1	5.1
Moxifloxacin	15	5.1	5.1
Rabeprazole	23	5.0	5.0
Standardized Senna Concentrate	13	5.0	5.0
Voriconazole	31	4.9	4.9
Azelastine	18	4.8	4.8
Cetiirizine	42	4.8	4.8
Amiodarone Hydrochloride	11	4.7	4.7
Mycophenolate Mofetil	128	4.6	4.6
Mycophenolate Mofetil Hydrochloride	128	4.6	4.6
Cetirizine	71	4.4	4.4
Cetirizine Hydrochloride	145	4.3	4.3
Cyanocobalamin	29	4.2	4.2
Oseltamivir	7	4.2	4.2
Felodipine Extended-Release Tablets	10	4.2	4.2
Felodipine	10	4.2	4.2
Mometasone	16	4.2	4.2
Cetirizine Hcl	8	4.2	4.2
Piperacillin Sodium And Tazobactam Sodium	17	4.2	4.2
Minocycline	10	4.1	4.1
Febuxostat	14	4.0	4.0
Remdesivir	11	4.0	4.0
Dexlansoprazole	34	3.9	3.9
Posaconazole	13	3.8	3.8
Cetirizine Hydrochloride Allergy	24	3.8	3.8
Cetirizine Hydrochloride Tablets	24	3.8	3.8
Sulfamethoxazole And Trimethoprim	65	3.7	3.7
Fluticasone Propionate Nasal	23	3.7	3.7
Atovaquone	6	3.6	3.6
Ergocalciferol	274	3.6	3.6
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	117	3.6	3.6
Valganciclovir Hydrochloride Powder,	9	3.5	3.5
Desoximetasone	14	3.5	3.5
Posaconazole Delayed-Release	8	3.5	3.5
Umeclidinium Bromide And Vilanterol Trifenatate	12	3.4	3.5
Polatuzumab Vedotin	7	3.4	3.4
Bendamustine Hcl	11	3.4	3.4
Cefepime	10	3.3	3.4
Guaifenesin	21	3.3	3.3
Mycophenolic Acid	22	3.3	3.3
Mycophenilic Acid	14	3.2	3.2
Linezolid	20	3.2	3.2
Polyethylene Glycol 3350	62	3.1	3.1
Cefepime Hydrochloride	10	3.0	3.0
Dutasteride	5	2.9	3.0
Dronedarone	6	2.8	2.8
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	2.8	2.8
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	2.8	2.8
Imatinib	10	2.7	2.7
Insulin Aspart	35	2.6	2.6
Sevoflurane	4	2.3	2.3
Atomoxetine Hydrochloride	11	2.2	2.2
Rocuronium Bromide	5	2.0	2.0
Alteplase	6	1.9	1.9
Aflibercept	12	1.8	1.8
Ambrisentan	45	1.7	1.7
Treprostinil	41	1.6	1.6
Glecaprevir And Pibrentasvir	3	1.3	1.3
Dupilumab	54	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.