Reaction

Rosacea reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,573 reports · 143 co-occurring drugs

As of the last recalculation, Rosacea appears in 4,573 FAERS reports alongside 143 co-occurring drug terms. The strongest observed disproportionality signal is BRIMONIDINE TARTRATE (PRR 48.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Brimonidine Tartrate	183	48.7	49.2
Doxyclycline Hyclate	55	14.9	14.9
Doxycycline	184	12.7	12.8
Metronidazole Topical	116	11.3	11.4
Doxycycline Hyclate	161	11.2	11.2
Sulfur	19	10.3	10.3
Metronidazole	140	10.3	10.3
Clobetasol Propionate Ointment Usp, 0.05%	23	10.2	10.2
Clobetasol Propionate	23	10.2	10.2
Minocycline	23	9.0	9.0
Calcium, Magnesium, Potassium, And Sodium Oxybates	16	8.5	8.5
Ketoconazole Foam	25	7.7	7.7
Ketoconazole Cream, 2%	25	7.7	7.7
Ketoconazole	29	7.7	7.7
Terbinafine Hydrochloride	14	7.2	7.2
Meperidine Hydrochloride	14	6.9	6.9
Adapalene	263	6.9	6.9
Mometasone	27	6.7	6.7
Triamcinolone Acetonide Ointment Usp, 0.05%	34	6.7	6.7
Methylprednisolone Acetate	11	6.3	6.3
Tretinoin	11	6.2	6.2
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	40	6.1	6.1
Salicylic Acid	64	5.6	5.6
Biotin	37	5.4	5.4
Diphenhydramine Hydrochloride Capsule, Liquid Filled	25	5.3	5.4
Triamcinolone Acetonide	36	5.3	5.3
Liothyronine Sodium	10	5.2	5.2
Crisaborole	11	5.2	5.2
Clindamycin Phosphate	38	5.2	5.2
Alendronate Sodium	112	5.2	5.2
Zinc Gluconate	28	4.9	4.9
Zinc	26	4.8	4.8
Zinc Chloride	26	4.8	4.8
Mometasone Furoate	42	4.6	4.6
Sodium Oxybate	63	4.4	4.4
Dapsone	10	4.3	4.3
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	44	4.0	4.0
Clindamycin	25	4.0	4.0
Upadacitinib	71	4.0	4.0
Hyoscyamine Sulfate	8	4.0	4.0
Fluticasone Propionate Nasal	26	3.9	3.9
Erythromycin	16	3.9	3.9
Thyroid, Porcine	9	3.9	3.9
Desloratadine	9	3.8	3.8
Methocarbamol	19	3.8	3.8
Vitamin C	76	3.8	3.8
Azelastine	15	3.8	3.8
Ibuprofen Tablets, Coated	35	3.8	3.8
Infliximab-Dyyb	24	3.8	3.8
Hydroxychloroquine Sulfate	74	3.7	3.7
Ibuprofen Sodium	35	3.7	3.7
Mupirocin	11	3.7	3.7
Buspirone Hydrochloride	9	3.7	3.7
Diphenoxylate Hydrochloride And Atropine Sulfate	11	3.7	3.7
Mupirocin Calcium	11	3.6	3.7
Dupilumab	359	3.6	3.6
Febuxostat Tablets 40 Mg	8	3.6	3.6
Febuxostat Tablets 80 Mg	8	3.6	3.6
Rizatriptan Benzoate	8	3.6	3.6
Estradiol Gel 0.1%	35	3.5	3.5
Estradiol Transdermal	35	3.5	3.5
Losartan Potassium And Hydrochlorothiazide	9	3.5	3.5
Cetirizine Hydrochloride Allergy	23	3.5	3.5
Cetirizine Hydrochloride Tablets	23	3.5	3.5
Hydroxyzine Hydrochloride	10	3.5	3.5
Hydroxyzine Hydrochloride Oral	10	3.5	3.5
Fish Oil	66	3.4	3.4
Isotretinoin	36	3.3	3.3
Fluticasone Propionate	93	3.3	3.3
Brexpiprazole	12	3.3	3.3
Adalimumab-Fkjp	32	3.2	3.2
Raloxifene Hydrochloride	10	3.1	3.1
Tofacitinib	124	3.1	3.1
Desoximetasone	13	3.1	3.1
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	24	3.1	3.1
Adalimumab-Aaty	32	3.1	3.1
Sumatriptan Succinate	17	3.1	3.1
Adalimumab-Adaz	35	3.0	3.0
Febuxostat	11	3.0	3.0
Loratadine Tablet	35	3.0	3.0
Cetirizine Hcl	6	3.0	3.0
Aprepitant	12	3.0	3.0
Omalizumab	55	3.0	3.0
Finasteride	39	3.0	3.0
Estradiol	55	2.9	2.9
Montelukast	53	2.9	2.9
Multivitamin	31	2.8	2.8
Armodafinil	13	2.8	2.8
Fexofenadine	10	2.8	2.8
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	25	2.8	2.8
Sumatriptan	22	2.6	2.6
Ruxolitinib	41	2.6	2.6
Lifitegrast	9	2.5	2.5
Vilazodone Hydrochloride	5	2.5	2.5
Levocetirizine Dihydrochloride	13	2.5	2.5
Certolizumab Pegol	61	2.4	2.4
Ravulizumab	7	2.4	2.4
Ocrelizumab	32	2.4	2.4
Secukinumab	81	2.3	2.3
Dexlansoprazole	21	2.3	2.3
Diroximel Fumarate	6	2.3	2.3
Loratadine And Pseudoephedrine Sulfate	4	2.3	2.3
Cortisone Acetate	6	2.2	2.2
Abaloparatide	14	2.2	2.2
Rucaparib	4	2.1	2.1
Dimethyl Fumarate	54	2.0	2.0
Vedolizumab	37	2.0	2.0
Fingolimod Hcl	36	1.9	1.9
Methylphenidate	12	1.9	1.9
Golimumab	35	1.9	1.9
Asfotase Alfa	4	1.8	1.8
Rimegepant Sulfate	5	1.8	1.8
Dronedarone	4	1.8	1.8
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.8	1.8
Belimumab	12	1.7	1.7
Denosumab	76	1.7	1.7
Vibegron	3	1.7	1.7
Diclofenac Potassium	4	1.7	1.7
Romosozumab-Aqqg	5	1.7	1.7
Diclofenac Potassium, Film Coated	3	1.6	1.6
Diclofenac Potassium Tablets	3	1.6	1.6
Ixekizumab	13	1.6	1.6
Fremanezumab-Vfrm	4	1.6	1.6
Bimatoprost	10	1.6	1.6
Cannabidiol	8	1.6	1.6
Ofatumumab	11	1.5	1.5
Erenumab-Aooe	18	1.5	1.5
Elexacaftor, Tezacaftor, And Ivacaftor	4	1.5	1.5
Alirocumab	8	1.5	1.5
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	13	1.4	1.4
Bimekizumab	6	1.3	1.3
Minoxidil Foam 5% (Womens)	9	1.2	1.2
Onabotulinumtoxina	21	1.2	1.2
Dasatinib	10	1.2	1.2
Sarilumab	7	1.2	1.2
Dalfampridine	19	1.2	1.2
Apremilast	33	1.0	1.0
Minoxidil	10	1.0	1.0
Pirfenidone	9	1.0	1.0
Guselkumab	7	0.9	0.9
Pegfilgrastim	18	0.8	0.8
Levonorgestrel	34	0.8	0.8
Nirmatrelvir And Ritonavir	9	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.