Reaction

Ventricular Septal Defect reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,687 reports · 147 co-occurring drugs

As of the last recalculation, Ventricular Septal Defect appears in 5,687 FAERS reports alongside 147 co-occurring drug terms. The strongest observed disproportionality signal is NEVIRAPINE (PRR 44.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Nevirapine	107	44.2	44.7
Zidovudine	152	42.7	43.2
Paroxetine Hydrochloride	855	40.3	40.7
Misoprostol	97	37.1	37.4
Nicotine Polacrilex Mini	89	22.0	22.2
Nicotine Polarilex	89	22.0	22.2
Lopinavir And Ritonavir	76	20.8	20.9
Ampicillin	46	20.5	20.6
Ampicillin Sodium	46	20.5	20.6
Tenofovir Disoproxil Fumarate Tablets	47	20.1	20.2
Atazanavir	71	18.3	18.4
Lamotirigine	295	15.8	15.9
Lamotrigine Extended-Release	295	15.8	15.9
Lamotrigine Chewable Dispersible	295	15.8	15.9
Progesterone	91	14.8	14.8
Ritonavir	114	14.6	14.6
Lamivudine Oral	94	13.8	13.9
Dalteparin Sodium	39	13.6	13.6
Lamivudine	109	13.1	13.2
Sertraline Hydrochloride	368	12.1	12.1
Valproic Acid	98	11.6	11.6
Darunavir	46	11.2	11.2
Lamotrigine	377	11.1	11.2
Dimenhydrinate	31	10.7	10.7
Levetiracetam In Sodium Chloride	198	9.7	9.7
Levetiracetam Oral	198	9.7	9.7
Levetiracetam Injection	198	9.7	9.7
Promethazine Hydrochloride	46	9.1	9.1
Ritonavir 100 Mg	37	9.1	9.1
Aripiprazole Oral	100	9.0	9.0
Aripiprazole Orally Disintegrating	100	9.0	9.0
Fluoxetine Hydrochloride	295	8.9	8.9
Valproate Sodium	49	8.7	8.8
Nicotine Polacrilex	89	8.6	8.6
Nicotine	93	8.5	8.6
Oseltamivir	18	8.3	8.3
Venlafaxine	152	8.0	8.0
Raltegravir	32	7.1	7.1
Citalopram Hydrobromide	200	7.0	7.1
Emtricitabine And Tenofovir Disoproxil Fumarate	86	7.0	7.0
Paroxetine Hydrochloride Hemihydrate	63	7.0	7.0
Levetiracetam	245	7.0	7.0
Paroxetine	63	6.8	6.9
Tenofovir Disoproxil Fumarate	61	6.8	6.8
Cefuroxime	21	6.7	6.8
Sertraline	205	6.6	6.6
Citalopram	229	6.3	6.3
Palivizumab	26	6.2	6.2
Venlafaxine Hydrochloride	211	6.0	6.0
Clobazam	39	5.9	5.9
Phenobarbital	22	5.6	5.6
Escitslopram	83	5.3	5.3
Folic Acid	341	5.3	5.3
Magnesium Sulfate In Water For	18	5.2	5.2
Magnesium Sulfate Heptahydrate	18	5.1	5.1
Magnesium Sulfate	18	5.1	5.1
Enoxaparin Sodium	78	5.0	5.0
Torsemide	45	5.0	5.0
Carbamazepine	89	4.9	4.9
Aripiprazole	159	4.9	4.9
Escitalopram	181	4.8	4.8
Ramipril	156	4.7	4.7
Escitalopram Oxalate	92	4.7	4.7
Miconazole Nitrate	11	4.6	4.6
Amoxicillin	93	4.5	4.5
Amphotericin B	15	4.4	4.4
Lithium	30	4.4	4.4
Lithium Bromatum	30	4.4	4.4
Topiramate	109	4.3	4.3
Dolutegravir Sodium	10	4.1	4.1
Meclizine	18	4.0	4.0
Insulin	61	4.0	4.0
Fluoxetine	72	4.0	4.0
Azithromycin Dihydrate	63	4.0	4.0
Valsartan Oral	58	3.9	3.9
Meclizine Hydrochloride	21	3.9	3.9
Labetalol	14	3.9	3.9
Hydroxychloroquine	77	3.8	3.8
Captopril	10	3.8	3.8
Ondansetron Hydrochloride	124	3.8	3.8
Oseltamivir Phosphate	25	3.8	3.8
Nifedipine	48	3.7	3.7
Cephalexin	22	3.7	3.7
Zonisamide	15	3.7	3.7
Ferrous Sulfate	50	3.7	3.7
Mometasone	18	3.6	3.6
Meperidine Hydrochloride	9	3.6	3.6
Quetiapine	183	3.6	3.6
Ezetimibe	72	3.5	3.5
Meclizine Hcl 12.5Mg	13	3.5	3.5
Meclizine Hcl 25Mg	13	3.5	3.5
Meclizine Hcl 12.5 Mg	13	3.5	3.5
Meclizine Hcl 25 Mg	13	3.5	3.5
Diazepam Oral Solution (Concentrate)	84	3.5	3.5
Diazepam Oral	84	3.5	3.5
Norepinephrine	10	3.4	3.4
Oxcarbazepine	30	3.4	3.4
Erythromycin	17	3.3	3.3
Levothyroxine Sodium Anhydrous	89	3.3	3.3
Duloxetine	61	3.2	3.2
Metoclopramide Hydrochloride	65	3.1	3.1
Ondansetron	91	3.1	3.1
Ondansetron Tablets	91	3.1	3.1
Ibuprofen Capsule	163	3.0	3.1
Ibuprofen Tablet, Film Coated	163	3.0	3.1
Ibupfrofen	163	3.0	3.1
Ibuprofen Tablets Usp, 200Mg	163	3.0	3.1
Ibuprofen Oral	163	3.0	3.1
Ibuprofen Capsules 200 Mg	163	3.0	3.0
Ibuprofen 200 Mg	163	3.0	3.0
Ibuprofen 200Mg	163	3.0	3.0
Prednisolone	142	2.9	2.9
Prednisolone Oral	142	2.9	2.9
Prednisolone Oral Solution	142	2.9	2.9
Iron	52	2.9	2.9
Eplerenone	10	2.9	2.9
Divalproex Sodium	36	2.8	2.8
Diazepam	93	2.8	2.8
Metoclopramide	42	2.8	2.8
Norepinephrine Bitartrate	11	2.8	2.8
Tacrolimus Ointment 0.1%	92	2.7	2.7
Tacrolimus Extended-Release Capsules	92	2.7	2.7
Ibuprofen	193	2.7	2.7
Phenytoin	15	2.6	2.6
Bupropion Hydrochloride	70	2.6	2.6
Sumatriptan	27	2.6	2.6
Oxazepam	15	2.6	2.6
Tacrolimus	108	2.6	2.6
Ibuprofen And Diphenhydramine Citrate	16	2.5	2.5
Naproxen Sodium Tablet, Coated	9	2.4	2.4
Naproxen Sodium, Coated Tablets	9	2.4	2.4
Naproxen Sodium 220Mg	9	2.4	2.4
Emtricitabine And Tenofovir Alafenamide	7	2.3	2.3
Tobramycin Solution	7	2.1	2.1
Tobramycin Sulfate	7	2.1	2.1
Isotretinoin	27	2.0	2.0
Prochlorperazine	15	2.0	2.0
Efavirenz	6	2.0	2.0
Lacosamide	16	1.6	1.6
Risperidone	57	1.6	1.6
Rivaroxaban	89	1.6	1.6
Botulinum Toxin Type A	5	1.5	1.5
Fingolimod Hcl	33	1.4	1.4
Belimumab	10	1.2	1.2
Glatiramer Acetate	16	1.0	1.0
Drospirenone And Ethinyl Estradiol	11	0.9	0.9
Salicylic Acid	10	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.