Reaction

Anal Fistula reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,265 reports · 113 co-occurring drugs

As of the last recalculation, Anal Fistula appears in 5,265 FAERS reports alongside 113 co-occurring drug terms. The strongest observed disproportionality signal is INFLIXIMAB-DYYB (PRR 56.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Infliximab-Dyyb	388	56.6	57.3
Isotretinoin	321	27.3	27.4
Vedolizumab	530	26.9	27.1
Azathioprine	530	26.3	26.5
Infliximab	965	21.2	21.3
Metronidazole	316	20.7	20.8
Mesalamine	243	17.9	18.0
Adalimumab-Fkjp	198	17.5	17.6
Ciprofloxacin Hydrochloride And Hydrocortisone	89	17.2	17.3
Adalimumab-Aaty	189	16.3	16.4
Adalimumab-Adaz	194	15.1	15.1
Adalimumab	1,646	12.9	13.0
Dimenhydrinate	33	12.3	12.3
Mercaptopurine	53	12.2	12.2
Ciprofloxacin Hydrochloride	278	11.9	11.9
Ciprofloxacin	263	11.9	11.9
Metronidazole Topical	132	11.2	11.2
Ustekinumab	261	10.6	10.6
Ciprofolxacin	176	10.0	10.0
Ciprofloxacin Tablets	176	10.0	10.0
Cholestyramine	24	7.9	7.9
Hydrocortisone Sodium Succinate	17	7.2	7.2
Hydrocortisone	149	6.8	6.8
Anti-Itch	108	6.5	6.5
Anti-Pruritic	108	6.5	6.5
Antipruritic (Anti-Itch)	108	6.5	6.5
Cool Relief Gel With Aloe	108	6.5	6.5
Drs. Hydrocortisone	108	6.5	6.5
Hydrocortisone Continuous Spray	108	6.5	6.5
Hydrocortisone Spray	108	6.5	6.5
Anti-Itch Cream	108	6.5	6.5
Hydrocortisone Lotion	108	6.5	6.5
Hydrocortisone Cream 1%	108	6.5	6.5
Hydrocortisone Cream 1/2%	108	6.5	6.5
Hydrocortisone 1%	108	6.5	6.5
Hydrocortisone Cream	108	6.4	6.5
Hydrocortisone Acetate	111	6.1	6.2
Diphenoxylate Hydrochloride And Atropine Sulfate	21	6.1	6.1
Loperamide Hydrochloride And Dimethicone	46	5.7	5.7
Bevacizumab	171	5.6	5.6
Loperamide Hydrochloride	59	5.3	5.3
Psyllium Husk	13	5.2	5.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled	28	5.2	5.2
Regorafenib	15	5.1	5.1
Dalteparin Sodium	13	4.9	4.9
Upadacitinib	96	4.7	4.7
Dicyclomine Hydrochloride	16	4.5	4.5
Sulfasalazine	86	4.4	4.4
Hyoscyamine Sulfate	10	4.3	4.3
Loperamide Hcl	14	4.3	4.3
Iron	72	4.3	4.3
Loperamide Hydrochloride Oral	11	4.3	4.3
Methotrexate Sodium	487	4.3	4.3
Clindamycin	30	4.2	4.2
Diphenhydramine	66	4.2	4.2
Methotrexate	408	4.1	4.1
Basiliximab	12	4.0	4.0
Leucovorin Calcium	19	3.9	3.9
Prednisone	468	3.9	3.9
Doxepin	10	3.9	3.9
Sunitinib Malate	38	3.8	3.8
Folic Acid	233	3.8	3.8
Certolizumab Pegol	111	3.8	3.8
Budesonide	54	3.7	3.7
Pantoprazole Sodium In 0.9% Sodium Chloride	56	3.6	3.6
Pantoprazole Sodium Injection	56	3.6	3.6
Panitumumab	14	3.5	3.5
Desoximetasone	17	3.5	3.5
Tamsulosin Hydrochloride	18	3.5	3.5
Azacitidine For	16	3.5	3.5
Diltiazem Hydrochloride Extended-Release Tablets	10	3.5	3.5
Doxepin Hydrochloride	11	3.4	3.5
Clindamycin Phosphate	29	3.4	3.4
Risankizumab-Rzaa	68	3.3	3.3
Diphenhydramine Hydrochloride	136	3.3	3.3
Lenvatinib	27	3.3	3.3
Acetaminophen And Codeine	10	3.2	3.3
Fluorouracil Cream, 0.5%	62	3.2	3.2
Fluorouracil	62	3.2	3.2
Azacitidine	23	3.1	3.1
Cabozantinib	37	3.1	3.1
Teduglutide	10	2.9	2.9
Tretinoin	6	2.9	2.9
Ferrous Sulfate	36	2.8	2.8
Tizanidine	17	2.8	2.8
Oxaliplatin	50	2.7	2.7
Sorafenib	14	2.7	2.7
Posaconazole Delayed-Release	7	2.5	2.5
Atezolizumab	24	2.4	2.5
Dutasteride	5	2.4	2.4
Dapagliflozin	19	2.4	2.4
Minocycline	7	2.4	2.4
Bosutinib	5	2.2	2.2
Posaconazole	9	2.2	2.2
Lisdexamfetamine Dimesylate	18	2.2	2.2
Irinotecan Hydrochloride	7	2.2	2.2
Pazopanib Hydrochloride	14	2.0	2.0
Ticagrelor	16	2.0	2.0
Multivitamin	25	2.0	2.0
Golimumab	41	1.9	1.9
Trifluridine And Tipiracil	5	1.8	1.8
Capecitabine	42	1.8	1.8
Entecavir	5	1.7	1.7
Desvenlafaxine Succinate	11	1.6	1.6
Rifaximin	8	1.5	1.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	1.3	1.3
Ipilimumab	14	1.3	1.3
Axitinib	6	1.2	1.2
Orlistat	5	0.8	0.8
Pegfilgrastim	19	0.8	0.8
Guselkumab	6	0.7	0.7
Nirmatrelvir And Ritonavir	8	0.6	0.6
Adapalene	5	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.