Reaction

Organ Failure reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,998 reports · 87 co-occurring drugs

As of the last recalculation, Organ Failure appears in 3,998 FAERS reports alongside 87 co-occurring drug terms. The strongest observed disproportionality signal is DROSPIRENONE AND ETHINYL ESTRADIOL (PRR 19.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Drospirenone And Ethinyl Estradiol	161	19.7	19.8
Micafungin Sodium	18	11.1	11.1
Posaconazole Delayed-Release	20	9.5	9.5
Cefazolin	16	9.2	9.2
Ganciclovir	17	8.7	8.7
Ganciclovir Sodium	17	8.4	8.4
Norepinephrine Bitartrate	23	8.4	8.4
Remdesivir	19	7.5	7.5
Dalteparin Sodium	15	7.4	7.4
Cefazolin Sodium	16	6.9	6.9
Heparin Sodium	18	6.8	6.8
Posaconazole	21	6.8	6.8
Vancomycin	73	6.7	6.7
Vancomycin Hydrochloride	79	6.3	6.4
Ampicillin	10	6.3	6.3
Ampicillin Sodium	10	6.3	6.3
Voriconazole Injection	26	6.3	6.3
Linezolid	34	6.0	6.0
Busulfan	17	5.6	5.6
Valganciclovir Hydrochloride Powder,	13	5.6	5.6
Meropenem	34	5.6	5.6
Cefuroxime	12	5.5	5.5
Cefepime	15	5.5	5.5
Sunitinib Malate	40	5.3	5.3
Nitroglycerin	52	5.1	5.1
Meperidine Hydrochloride	9	5.1	5.1
Voriconazole	29	5.0	5.0
Amphotericin B	12	5.0	5.0
Amikacin	16	4.9	4.9
Piperacillin And Tazobactam	12	4.9	4.9
Cefepime Hydrochloride	15	4.9	4.9
Piperacillin Sodium And Tazobactam Sodium	18	4.8	4.8
Thiotepa	8	4.4	4.4
Glyburide	20	4.3	4.3
Ribociclib	26	4.3	4.3
Erlotinib	8	4.3	4.3
Midazolam Hydrochloride	22	4.3	4.3
Fludarabine Phosphate	32	4.3	4.3
Rifaximin	17	4.2	4.2
Propofol	29	4.2	4.2
Midazolam	20	4.1	4.1
Dronedarone	8	4.1	4.1
Filgrastim	29	4.0	4.0
Dicyclomine Hydrochloride	11	4.0	4.0
Norepinephrine	8	3.9	3.9
Valganciclovir	14	3.9	3.9
Valganciclovir Hydrochloride	14	3.9	3.9
Everolimus Tablets	12	3.7	3.7
Adrenalinum	29	3.7	3.7
Enoxaparin Sodium	39	3.6	3.6
Tafamidis	8	3.5	3.5
Phenytoin	14	3.5	3.5
Erlotinib Hydrochloride	8	3.3	3.3
Nilotinib	18	3.2	3.2
Piperacillin Sodium,Tazobactam Sodium	16	3.1	3.2
Hydrocodone Bitartrate And Acetaminophen	33	3.1	3.1
Bendamustine Hcl	9	3.0	3.0
Blinatumomab	6	3.0	3.0
Deferasirox	15	3.0	3.0
Fentanyl Citrate	10	2.9	2.9
Epoprostenol	7	2.8	2.8
Sorafenib	10	2.5	2.5
Romiplostim	7	2.4	2.4
Alpelisib	4	2.4	2.4
Bendamustine Hydrochloride	5	2.2	2.2
Tobramycin	10	2.2	2.2
Acalabrutinib	5	2.1	2.1
Polatuzumab Vedotin	4	2.1	2.1
Bosentan	20	2.1	2.1
Hydrocodone Bitartrate	16	1.9	1.9
Ethyl Alcohol	10	1.9	1.9
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	1.9	1.9
Crizotinib	4	1.6	1.6
Venetoclax	19	1.6	1.6
Axicabtagene Ciloleucel	3	1.6	1.6
Benralizumab	6	1.6	1.6
Fam-Trastuzumab Deruxtecan-Nxki	3	1.5	1.6
Ambrisentan	36	1.5	1.5
Trifluridine And Tipiracil	3	1.5	1.5
Ledipasvir And Sofosbuvir	5	1.4	1.4
Oxymorphone Hydrochloride	3	1.3	1.3
Emicizumab	3	1.3	1.3
Olaparib	5	1.2	1.2
Esketamine Hydrochloride	4	1.2	1.2
Aflibercept	6	1.0	1.0
Pomalidomide	16	0.8	0.8
Voxelotor	3	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.