OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Ototoxicity reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,830 reports · 72 co-occurring drugs

As of the last recalculation, Ototoxicity appears in 1,830 FAERS reports alongside 72 co-occurring drug terms. The strongest observed disproportionality signal is AMIKACIN (PRR 135.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Amikacin183135.5136.9
Gentamicin Sulfate137106.5107.4
Gentamicin9486.186.7
Tobramycin Solution8180.280.7
Tobramycin Sulfate8379.880.4
Moxifloxacin7361.361.7
Cisplatin31354.855.0
Linezolid12249.950.1
Tobramycin9647.948.0
Moxifloxacin Hydrochloride7644.444.6
Pyrazinamide3543.243.3
Rifampin4838.438.5
Vincristine Sulfate8835.835.9
Etoposide18932.532.6
Clarithromycin8629.829.9
Mesna Injection2129.229.3
Mesna2128.728.8
Azithromycin9227.327.4
Azithromycin Monohydrate9326.726.8
Carboplatin25526.426.4
Polatuzumab Vedotin2225.926.0
Ifosfamide4222.722.8
Bleomycin Sulfate2022.322.3
Vancomycin10622.122.1
Rifampicin1921.621.6
Vancomycin Hydrochloride11721.521.5
Erythromycin3320.420.4
Azithromycin Dihydrate9719.819.8
Bendamustine Hcl2619.319.4
Meropenem5319.319.3
Minocycline1918.718.7
Pemetrexed3116.716.7
Cefazolin1316.316.3
Isoniazid2215.615.6
Piperacillin And Tazobactam1513.413.5
Pemetrexed Disodium4313.113.1
Cefazolin Sodium1312.312.4
Melphalan2311.611.6
Ampicillin811.011.0
Ampicillin Sodium811.011.0
Gemcitabine Hydrochloride5011.011.0
Gemcitabine3710.910.9
Melphalan Hydrochloride2310.610.6
Fosaprepitant Dimeglumine1210.010.0
Ceftriaxone289.89.8
Doxorubicin729.59.5
Azacitidine For159.49.5
Paclitaxel (Aibumin-Bound)669.49.4
Piperacillin Sodium And Tazobactam Sodium169.39.4
Doxorubicin Hydrochloride269.29.2
Ceftriaxone Sodium298.78.7
Atovaquone68.58.5
Cyclophosphamide Injection, Solution1238.48.4
Cyclophosphamide1238.48.4
Cyclophosphamide For Injection1238.48.4
Posaconazole Delayed-Release88.38.3
Piperacillin Sodium,Tazobactam Sodium198.28.2
Paclitaxel698.28.2
Micafungin Sodium68.18.1
Cytarabine417.97.9
Selinexor67.97.9
Aprepitant127.47.4
Voriconazole Injection136.96.9
Nevirapine56.36.3
Daptomycin56.26.2
Temozolomide116.06.0
Entecavir65.95.9
Azacitidine155.85.8
Durvalumab105.65.6
Olaparib84.44.4
Carfilzomib104.04.0
Dornase Alfa52.92.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.