Reaction

Gastrointestinal Necrosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,865 reports · 93 co-occurring drugs

As of the last recalculation, Gastrointestinal Necrosis appears in 2,865 FAERS reports alongside 93 co-occurring drug terms. The strongest observed disproportionality signal is PEGASPARGASE (PRR 16.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pegaspargase	27	16.2	16.2
Norepinephrine Bitartrate	31	15.8	15.8
Norepinephrine	23	15.8	15.8
Vincristine Sulfate	54	13.6	13.6
Basiliximab	21	13.1	13.1
Fluorouracil Cream, 0.5%	117	11.6	11.6
Fluorouracil	117	11.4	11.4
Theophylline	17	10.8	10.8
Ganciclovir	15	10.7	10.7
Ganciclovir Sodium	15	10.3	10.4
Cytarabine	82	10.2	10.2
Docetaxel Anhydrous	91	10.1	10.1
Docetaxel	91	10.1	10.1
Theophylline Anhydrous	17	10.0	10.0
Polyethylene Glycol	14	9.4	9.4
Granisetron Hydrochloride	13	9.1	9.1
Sevelamer Carbonate	14	8.9	8.9
Granisetron	12	8.3	8.4
Cetuximab	33	7.7	7.7
Sucralfate Oral	15	7.7	7.7
Sucralfate Oral Suspension	15	7.7	7.7
Valproate Sodium	21	7.4	7.4
Fosaprepitant Dimeglumine	14	7.4	7.4
Aprepitant	18	7.1	7.1
Brentuximab Vedotin	10	7.1	7.1
Heparin Sodium	13	6.9	6.9
Bevacizumab	113	6.9	6.9
Piperacillin And Tazobactam	12	6.8	6.8
Eplerenone	12	6.8	6.8
Valproic Acid	29	6.7	6.7
Piperacillin Sodium And Tazobactam Sodium	18	6.7	6.7
Cisplatin	68	6.5	6.5
Candesartan Cilexetil	23	6.4	6.4
Phenytoin	18	6.3	6.3
Fondaparinux Sodium	7	6.3	6.3
Oxaliplatin	63	6.3	6.3
Etoposide	62	6.2	6.2
Irinotecan Hydrochloride	11	6.2	6.2
Leucovorin Calcium	16	6.1	6.1
Clozapine	99	5.9	5.9
Methimazole	6	5.6	5.6
Busulfan	12	5.6	5.6
Cetirizine Hcl	7	5.6	5.6
Melphalan Hydrochloride	19	5.5	5.5
Anti-Thymocyte Globulin (Rabbit)	6	5.4	5.4
Pemetrexed Disodium	28	5.4	5.4
Haloperidol Lactate	18	5.3	5.3
Misoprostol	7	5.2	5.2
Piperacillin Sodium,Tazobactam Sodium	19	5.2	5.2
Micafungin Sodium	6	5.1	5.2
Melphalan	16	5.1	5.1
Haloperidol	17	5.1	5.1
Prasugrel Hydrochloride	7	5.0	5.0
Olanzapine	70	4.8	4.8
Meropenem	21	4.8	4.8
Oxazepam	14	4.7	4.8
Cyclophosphamide Injection, Solution	112	4.7	4.7
Cyclophosphamide	112	4.7	4.7
Cyclophosphamide For Injection	112	4.7	4.7
Tobramycin Sulfate	8	4.7	4.7
Suvorexant	8	4.5	4.5
Paclitaxel (Aibumin-Bound)	50	4.5	4.5
Polatuzumab Vedotin	6	4.5	4.5
Dabigatran Etexilate Mesylate	44	4.5	4.5
Capecitabine	55	4.4	4.4
Doxorubicin	52	4.3	4.3
Fludarabine Phosphate	23	4.3	4.3
Filgrastim	22	4.3	4.3
Erythropoietin	12	4.3	4.3
Paclitaxel	57	4.2	4.2
Tobramycin Solution	7	4.2	4.2
Carboplatin	71	4.1	4.1
Dabigatran Etexilate	42	4.0	4.0
Methoxy Polyethylene Glycol-Epoetin Beta	6	4.0	4.0
Ifosfamide	11	3.7	3.7
Lenvatinib	16	3.6	3.6
Bleomycin Sulfate	5	3.5	3.5
Sorafenib	10	3.5	3.5
Panitumumab	7	3.3	3.3
Ipilimumab	19	3.2	3.2
Apalutamide	5	3.1	3.1
Rotigotine	6	3.0	3.0
Axicabtagene Ciloleucel	4	2.9	2.9
Nintedanib	12	2.8	2.8
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	11	2.6	2.6
Pembrolizumab	37	2.6	2.6
Gefitinib	3	2.4	2.4
Lapatinib	5	2.3	2.3
Axitinib	6	2.2	2.2
Remdesivir	4	2.2	2.2
Durvalumab	6	2.1	2.1
Palivizumab	4	1.9	1.9
Droxidopa	3	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.