Reaction

Hypoxic-Ischaemic Encephalopathy reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,594 reports · 108 co-occurring drugs

As of the last recalculation, Hypoxic-Ischaemic Encephalopathy appears in 2,594 FAERS reports alongside 108 co-occurring drug terms. The strongest observed disproportionality signal is SEVOFLURANE (PRR 35.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Sevoflurane	36	35.2	35.4
Rocuronium Bromide	36	24.8	24.9
Atropine	23	22.5	22.5
Propofol	92	20.9	21.0
Norepinephrine Bitartrate	36	20.3	20.4
Norepinephrine	25	18.9	19.0
Atropine Sulfate	25	18.7	18.8
Amphetamine	19	18.6	18.6
Mesna Injection	16	15.6	15.7
Mesna	16	15.3	15.4
Dimenhydrinate	20	15.2	15.2
Methadone	77	14.8	14.9
Methadone Hydrochloride	19	14.2	14.2
Midazolam	40	12.9	12.9
Midazolam Hydrochloride	42	12.7	12.7
Iohexol	13	12.6	12.7
Adrenalinum	63	12.5	12.5
Haloperidol Lactate	37	12.2	12.2
Haloperidol	36	12.0	12.1
Dutasteride	9	8.9	8.9
Amantadine	17	8.9	8.9
Fentanyl	104	8.8	8.8
Magnesium Sulfate In Water For	13	8.2	8.2
Busulfan	16	8.2	8.2
Derma Foam Excel Hand Sanitizer	8	8.1	8.1
Magnesium Sulfate Heptahydrate	13	8.0	8.0
Magnesium Sulfate	13	8.0	8.0
Ethanol	8	8.0	8.0
Diazepam Oral Solution (Concentrate)	86	8.0	8.0
Diazepam Oral	86	8.0	8.0
Febuxostat Tablets 40 Mg	10	7.9	7.9
Febuxostat Tablets 80 Mg	10	7.9	7.9
Oxazepam	21	7.9	7.9
Epinephrine	63	7.9	7.9
Remdesivir	13	7.9	7.9
Phenytoin	20	7.7	7.7
Fentanyl Citrate	17	7.7	7.7
Dalteparin Sodium	10	7.6	7.6
Lidocaine Hydrochloride	56	7.6	7.6
Lidocaine Hydrochloride And Epinephrine Bitartrate	47	7.2	7.2
Piperacillin Sodium And Tazobactam Sodium	17	7.0	7.0
Temazepam	32	6.9	6.9
Diazepam	98	6.7	6.7
Misoprostol	8	6.6	6.6
Pravastatin Sodium	16	6.5	6.5
Rasagiline Mesylate	9	6.5	6.5
Amiodarone Hydrochloride	9	6.5	6.5
Ganciclovir	8	6.3	6.3
Sodium Bicarbonate	18	6.2	6.3
Sodium Bicarbonate Injection,	18	6.2	6.3
Ceftriaxone	25	6.2	6.2
Phenobarbital	11	6.1	6.1
Fexofenadine Hcl	7	6.1	6.1
Ganciclovir Sodium	8	6.1	6.1
Memantine	10	5.9	5.9
Memantine Hydrochloride	10	5.9	5.9
Heparin Sodium	10	5.9	5.9
Ceftriaxone Sodium	27	5.7	5.7
Digoxin	50	5.7	5.7
Selinexor	6	5.6	5.6
Alcohol	26	5.4	5.4
Testosterone Cypionate	6	5.4	5.4
Ethyl Alcohol	18	5.3	5.3
Meropenem	21	5.3	5.3
Metformin Hydrochloride Tablets	37	5.2	5.2
Metformin Hydrochloride Extended-Release Tablets	37	5.2	5.2
Metformin Hydrochloride Tablet	37	5.2	5.2
Lamotirigine	46	5.2	5.2
Lamotrigine Extended-Release	46	5.2	5.2
Lamotrigine Chewable Dispersible	46	5.2	5.2
Linezolid	19	5.2	5.2
Valproic Acid	20	5.1	5.1
Pseudoephedrine Hcl	7	5.1	5.1
Mycophenilic Acid	13	5.1	5.1
Nebivolol	10	5.1	5.1
Cefepime	9	5.1	5.1
Olanzapine	64	4.9	4.9
Febuxostat	10	4.8	4.8
Dronedarone	6	4.7	4.7
Cefepime Hydrochloride	9	4.5	4.5
Raltegravir	9	4.4	4.4
Fludarabine Phosphate	21	4.3	4.3
Isopropyl Alcohol	18	4.3	4.3
Darunavir	8	4.3	4.3
Sevelamer Carbonate	6	4.2	4.2
Levetiracetam In Sodium Chloride	40	4.2	4.2
Levetiracetam Oral	40	4.2	4.2
Levetiracetam Injection	40	4.2	4.2
Eszopiclone	13	4.1	4.1
Levetiracetam	64	3.9	3.9
Vigabatrin	7	3.9	3.9
Hydrocodone Bitartrate And Acetaminophen	26	3.7	3.7
Morphine Sulfate	51	3.4	3.4
Buprenorphine	37	3.2	3.2
Alteplase	6	3.2	3.2
Drospirenone And Ethinyl Estradiol	17	3.1	3.1
Buprenorphine Hydrochloride, Naloxone Hydrochloride	9	3.0	3.0
Pemetrexed	8	3.0	3.0
Tapentadol Hydrochloride	12	2.9	2.9
Brivaracetam	3	2.7	2.7
Dabigatran Etexilate	25	2.6	2.6
Carfilzomib	9	2.6	2.6
Dabigatran Etexilate Mesylate	23	2.6	2.6
Romosozumab-Aqqg	4	2.4	2.4
Methoxy Polyethylene Glycol-Epoetin Beta	3	2.2	2.2
Palivizumab	4	2.1	2.1
Emicizumab	3	1.9	1.9
Cinacalcet Hydrochloride	6	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.