Reaction

Obstruction reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,945 reports · 144 co-occurring drugs

As of the last recalculation, Obstruction appears in 3,945 FAERS reports alongside 144 co-occurring drug terms. The strongest observed disproportionality signal is TEDUGLUTIDE (PRR 82.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Teduglutide	200	82.4	83.7
Theophylline Anhydrous	124	54.4	55.0
Theophylline	114	53.9	54.4
Human Immunoglobulin G	115	30.3	30.4
Diphenhydramine Hydrochloride Capsule, Liquid Filled	114	29.0	29.1
Tamsulosin Hydrochloride	71	18.7	18.7
Risankizumab-Rzaa	263	18.1	18.2
Fluticasone Furoate	41	18.0	18.1
Adrenalinum	137	18.0	18.1
Ciclesonide	44	17.2	17.3
Calcium Gluconate	38	16.8	16.8
Fluticasone Furoate And Vilanterol Trifenatate	101	15.2	15.2
Mometasone	47	13.7	13.7
Diphenoxylate Hydrochloride And Atropine Sulfate	31	12.0	12.1
Mepolizumab	108	11.8	11.8
Epinephrine	139	11.6	11.6
Lidocaine	113	10.5	10.5
Ipratropium Bromide	68	10.2	10.2
Montelukast Sodium	221	10.1	10.1
Lidicaine	90	9.9	9.9
Burn Relief	90	9.9	9.9
Lidocaine Hydrochloride And Epinephrine	90	9.9	9.9
Lidocaine, Menthol	90	9.8	9.8
Finasteride	109	9.8	9.8
Moxifloxacin Hydrochloride	37	9.7	9.7
Trifluridine And Tipiracil	19	9.4	9.4
Olmesartan Medoxomil	62	9.2	9.2
Montelukast	140	9.1	9.1
Lidocaine Hydrochloride And Epinephrine Bitartrate	90	9.1	9.1
Diphenhydramine	105	9.0	9.0
Lidocaine 4%	90	8.9	8.9
Calcitriol Capsules 0.25 Mcg	32	8.5	8.5
Calcitriol Capsules 0.5 Mcg	32	8.5	8.5
Adalimumab	904	8.4	8.5
Infliximab-Dyyb	46	8.4	8.4
Calcitriol	32	8.4	8.4
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	32	8.3	8.3
Naproxen Sodium, Pseudoephedrine Hydrochloride	32	8.3	8.3
Cyclobenzaprine Hydrochloride	14	8.2	8.3
Hyoscyamine Sulfate	14	8.1	8.1
Lidocaine Hydrochloride	90	8.0	8.0
Tiotropium Bromide Inhalation Spray	17	8.0	8.0
Dimenhydrinate	16	8.0	8.0
Rosuvastatin Calcium	42	7.9	8.0
Albuterol	170	7.8	7.8
Sodium Chloride Tablet	105	7.7	7.7
Sodium Chloride Tablets	105	7.7	7.7
Sodium Chloride	111	7.6	7.6
Hydrocortisone Sodium Succinate	13	7.3	7.3
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	56	7.2	7.2
Cyanocobalamin	44	7.1	7.1
Methocarbamol	30	7.0	7.0
Loperamide Hydrochloride And Dimethicone	41	6.8	6.8
Benzonatate	21	6.7	6.7
Buspirone Hydrochloride	14	6.7	6.7
Azathioprine	108	6.6	6.6
Tiotropium Bromide	163	6.5	6.5
Apixaban	81	6.5	6.5
Umeclidinium	11	6.5	6.5
Azelastine	22	6.5	6.5
Fluticasone Propionate Nasal	37	6.5	6.5
Meperidine Hydrochloride	11	6.3	6.3
Infliximab	246	6.3	6.3
Upadacitinib	94	6.2	6.2
Albuterol Sulfate	323	6.2	6.2
Umeclidinium Bromide And Vilanterol Trifenatate	19	6.0	6.0
Loperamide Hydrochloride	50	6.0	6.0
Dicyclomine Hydrochloride	16	5.9	6.0
Guaifenesin	34	5.9	5.9
Tizanidine Hydrochloride	20	5.9	5.9
Budesonide And Formoterol Fumarate Dihydrate	105	5.8	5.8
Vedolizumab	93	5.8	5.8
Promethazine Hydrochloride	20	5.7	5.7
Methocarbamol Tablets	18	5.7	5.7
Prednisone	478	5.6	5.6
Budesonide, Glycopyrrolate, And Formoterol Fumarate	11	5.6	5.6
Octreotide Acetate	31	5.4	5.4
Doxyclycline Hyclate	17	5.3	5.3
Pantoprazole	241	5.3	5.3
Diphenhydramine Hydrochloride	155	5.1	5.1
Pantoprazole Sodium In 0.9% Sodium Chloride	59	5.1	5.1
Pantoprazole Sodium Injection	59	5.1	5.1
Budesonide	56	5.1	5.1
Acetylcysteine	9	5.0	5.1
Bisoprolol Fumarate	125	5.0	5.0
Letrozole Tablets	44	4.9	4.9
Liothyronine Sodium	8	4.9	4.9
Hydroxyzine Hydrochloride	12	4.8	4.8
Hydroxyzine Hydrochloride Oral	12	4.8	4.8
Pancrelipase	35	4.8	4.8
Cholestyramine	11	4.8	4.8
Mometasone Furoate	37	4.7	4.7
Cetirizine Hcl	8	4.6	4.6
Dronabinol	7	4.6	4.6
Doxazosin Mesylate	31	4.6	4.6
Polyethylene Glycol	9	4.4	4.4
Allopurinol	124	4.3	4.3
Oxybutynin Chloride	7	4.2	4.2
0Xygen	38	4.1	4.1
Oxygen	38	4.1	4.1
Letrozole	47	4.1	4.1
Iron	50	4.0	4.0
Melatonin	40	3.9	3.9
Heparin Sodium	10	3.8	3.8
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	114	3.8	3.8
Linaclotide	19	3.8	3.8
Ado-Trastuzumab Emtansine	6	3.8	3.8
Mometasone Furoate And Formoterol Fumarate Dihydrate	11	3.7	3.7
Fluticasone Propionate And Salmeterol Xinafoate	41	3.6	3.6
Rucaparib	6	3.6	3.6
Fluticasone Propionate	85	3.5	3.5
Hydromorphone Hydrochloride	59	3.4	3.4
Mesalamine	36	3.4	3.4
Ustekinumab	64	3.3	3.3
Cetirizine Hydrochloride Allergy	19	3.3	3.3
Cetirizine Hydrochloride Tablets	19	3.3	3.3
Loperamide Hcl	8	3.3	3.3
Regorafenib	7	3.2	3.2
Loperamide Hydrochloride Oral	6	3.1	3.1
Niraparib	13	3.1	3.1
Levocetirizine Dihydrochloride	14	3.1	3.1
Clozapine	68	2.9	2.9
Palivizumab	8	2.8	2.8
Capecitabine	46	2.7	2.7
Benralizumab	10	2.6	2.6
Omalizumab	42	2.6	2.6
Olaparib	10	2.5	2.5
Irinotecan Hydrochloride	6	2.5	2.5
Fesoterodine Fumarate	5	2.4	2.4
Fexofenadine Hydrochloride	10	2.4	2.4
Cetuximab	14	2.4	2.4
Erlotinib	4	2.2	2.2
Ticagrelor	13	2.2	2.2
Elexacaftor, Tezacaftor, And Ivacaftor	5	2.1	2.1
Erlotinib Hydrochloride	5	2.1	2.1
Oxaliplatin	29	2.1	2.1
Rivaroxaban	78	2.0	2.0
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	1.9	1.9
Lumacaftor And Ivacaftor	3	1.8	1.8
Cariprazine	3	1.7	1.7
Encorafenib	3	1.6	1.6
Patiromer	3	1.1	1.1
Tapentadol Hydrochloride	6	0.9	0.9
Relugolix	4	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.