Reaction

Poor Peripheral Circulation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,222 reports · 103 co-occurring drugs

As of the last recalculation, Poor Peripheral Circulation appears in 4,222 FAERS reports alongside 103 co-occurring drug terms. The strongest observed disproportionality signal is ICODEXTRIN, SODIUM CHLORIDE, SODIUM LACTATE, CALCIUM CHLORIDE, MAGNESIUM CHLORIDE (PRR 14.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	88	14.2	14.3
Ado-Trastuzumab Emtansine	19	11.2	11.2
Calcium Gluconate	24	9.9	9.9
Quinine	17	9.8	9.8
Trimethoprim	21	8.8	8.8
Insulin Human	69	8.7	8.7
Nitrofurantoin (Monohydrate/Macrocrystals)	26	7.7	7.7
Nitrofurantoin	25	7.5	7.5
Dimenhydrinate	16	7.4	7.4
Dicyclomine Hydrochloride	21	7.3	7.3
Chlorhexidine Gluconate	13	7.0	7.0
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	11	6.6	6.6
Atropine	11	6.6	6.6
Anastrozole Tablets	27	6.2	6.2
Eplerenone	16	6.2	6.2
Norepinephrine Bitartrate	17	5.8	5.8
Cimetidine	11	5.6	5.6
Nilotinib	33	5.6	5.6
Atropine Sulfate	12	5.5	5.5
Avapritinib	13	5.3	5.3
Valsartan And Hydrochlorothiazide	14	5.1	5.1
Heparin Sodium	14	5.0	5.0
Anastrozole	37	5.0	5.0
Cyclobenzaprine Hydrochloride	9	4.9	4.9
Exemestane	21	4.9	4.9
Aprepitant	18	4.8	4.8
Insulin Aspart	61	4.6	4.6
Amlodipine Besylate And Valsartan	10	4.5	4.5
Insulin	48	4.3	4.3
Iron Sucrose	8	4.1	4.1
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	25	4.1	4.1
Sacubitril And Valsartan	93	4.0	4.0
Mercaptopurine	14	4.0	4.0
Human Insulin	10	4.0	4.0
Bosentan	40	3.9	3.9
Sodium Bicarbonate	18	3.8	3.8
Sodium Bicarbonate Injection,	18	3.8	3.8
Ranibizumab	20	3.7	3.7
Norepinephrine	8	3.7	3.7
Senna Leaf	17	3.6	3.6
Pertuzumab	20	3.6	3.6
Clopidogrel	133	3.4	3.4
Ganciclovir	7	3.4	3.4
Zidovudine	9	3.3	3.3
Metformin Hcl	37	3.3	3.3
Ganciclovir Sodium	7	3.3	3.3
Pegaspargase	8	3.2	3.2
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	23	3.2	3.2
Insulin Lispro	89	3.2	3.2
Lisinopril And Hydrochlorothiazide Tablets	5	3.1	3.1
Pravastatin Sodium	12	3.0	3.0
Warfarin	76	3.0	3.0
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	25	3.0	3.0
Regorafenib	7	3.0	3.0
Sevoflurane	5	3.0	3.0
Vincristine Sulfate	17	2.9	2.9
Glipizide	34	2.8	2.8
Siponimod	5	2.8	2.8
Interferon Beta-1A	105	2.7	2.7
Lisdexamfetamine Dimesylate	18	2.7	2.7
Prochlorperazine Maleate	5	2.7	2.7
Risankizumab-Rzaa	44	2.7	2.7
Ravulizumab	7	2.6	2.6
Insulin Degludec	12	2.5	2.5
Sildenafil Citrate	64	2.5	2.5
Adalimumab	335	2.4	2.4
Apixaban	31	2.3	2.3
Calcium, Magnesium, Potassium, And Sodium Oxybates	4	2.3	2.3
Macitentan	32	2.3	2.3
Enzalutamide	27	2.3	2.3
Ibrutinib	37	2.3	2.3
Insulin Glargine	110	2.2	2.2
Sodium Oxybate	29	2.2	2.2
Patiromer	6	2.1	2.1
Paricalcitol	6	2.1	2.1
Atomoxetine Hydrochloride	10	2.1	2.1
Diroximel Fumarate	5	2.1	2.1
Treprostinil	50	2.0	2.0
Prasugrel Hydrochloride	4	1.9	1.9
Eltrombopag Olamine	9	1.9	1.9
Drospirenone And Ethinyl Estradiol	17	1.9	1.9
Dofetilide	4	1.9	1.9
Ruxolitinib	27	1.9	1.9
Loratadine And Pseudoephedrine Sulfate	3	1.9	1.9
Teriflunomide	16	1.7	1.7
Sevelamer Carbonate	4	1.7	1.7
Selinexor	3	1.7	1.7
Rucaparib	3	1.7	1.7
Teriparatide	37	1.6	1.6
Varenicline Tartrate	24	1.5	1.5
Cabozantinib	14	1.4	1.4
Exenatide	15	1.4	1.4
Ambrisentan	35	1.4	1.4
Cinacalcet Hydrochloride	13	1.4	1.4
Droxidopa	6	1.4	1.4
Palbociclib	24	1.2	1.2
Pegfilgrastim	21	1.0	1.0
Lenalidomide	88	1.0	1.0
Etonogestrel	9	0.9	0.9
Pomalidomide	19	0.9	0.9
Voxelotor	4	0.9	0.9
Abaloparatide	5	0.8	0.8
Relugolix	4	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.