Reaction

Tibia Fracture reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,648 reports · 126 co-occurring drugs

As of the last recalculation, Tibia Fracture appears in 4,648 FAERS reports alongside 126 co-occurring drug terms. The strongest observed disproportionality signal is EMTRICITABINE AND TENOFOVIR ALAFENAMIDE (PRR 24.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Emtricitabine And Tenofovir Alafenamide	62	24.8	24.9
Alendronate Sodium	428	20.8	20.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	41	20.6	20.7
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	40	18.0	18.0
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	71	17.8	17.9
Emtricitabine And Tenofovir Disoproxil Fumarate	149	15.1	15.1
Tenofovir Disoproxil Fumarate	85	11.7	11.7
Alendronate Sodium Tablet	45	11.0	11.0
Risedronate Sodium	68	9.9	9.9
Dolutegravir Sodium	19	9.5	9.5
Zoledronic Acid	77	8.7	8.7
Asfotase Alfa	17	7.6	7.6
Teriparatide	183	7.5	7.5
Raloxifene Hydrochloride	24	7.4	7.4
Amlodipine Besylate And Valsartan	17	6.9	6.9
Calcium Carbonate	95	6.4	6.5
Romosozumab-Aqqg	18	6.0	6.0
Rabeprazole	26	5.3	5.3
Ascorbic Acid	27	5.2	5.2
Vitamin E	36	5.2	5.2
Baricitinib	11	5.1	5.1
Tizanidine	27	5.1	5.1
Antacid	53	5.0	5.0
Cyclobenzaprine Hydrochloride	10	5.0	5.0
Rizatriptan Benzoate	11	4.9	4.9
Darunavir	16	4.8	4.8
Upadacitinib	84	4.7	4.7
Cimetidine	10	4.7	4.7
Calcium	150	4.6	4.6
Magnesium Hydroxide	13	4.3	4.3
Valsartan And Hydrochlorothiazide	13	4.3	4.3
Methocarbamol	21	4.2	4.2
Ritonavir	27	4.2	4.2
Cephalexin	20	4.2	4.2
Abacavir Sulfate	9	4.1	4.1
Denosumab	179	4.1	4.1
Buspirone Hydrochloride	10	4.1	4.1
Indomethacin	12	4.1	4.1
Interferon Beta-1A	167	4.0	4.0
Anastrozole Tablets	19	4.0	4.0
Tizanidine Hydrochloride	16	4.0	4.0
Primidone	9	4.0	4.0
Methotrexate	343	3.9	3.9
Dalfampridine	61	3.8	3.8
Methotrexate Sodium	391	3.8	3.8
Lubiprostone	8	3.8	3.8
Anakinra	14	3.8	3.8
Pioglitazone	36	3.7	3.8
Cyclobenzaprine	41	3.7	3.7
Lopinavir And Ritonavir	11	3.6	3.6
Meclizine Hcl 12.5Mg	11	3.6	3.6
Meclizine Hcl 25Mg	11	3.6	3.6
Meclizine Hcl 12.5 Mg	11	3.6	3.6
Meclizine Hcl 25 Mg	11	3.6	3.6
Meclizine	13	3.6	3.6
Risankizumab-Rzaa	63	3.5	3.5
Baclofen	66	3.5	3.5
Folic Acid	187	3.5	3.5
Meclizine Hydrochloride	15	3.4	3.4
Atazanavir	11	3.4	3.4
Anastrozole	28	3.4	3.4
Ergocalciferol	276	3.4	3.4
Modafinil	24	3.3	3.3
Benzonatate	12	3.3	3.3
Misoprostol	7	3.2	3.2
Insulin Human	28	3.2	3.2
Enoxaparin Sodium	40	3.1	3.1
Calcium, Magnesium, Potassium, And Sodium Oxybates	6	3.1	3.1
Phenobarbital	10	3.1	3.1
Infliximab-Dyyb	20	3.1	3.1
Siponimod	6	3.0	3.0
Raltegravir	11	3.0	3.0
Esomeprazole Magnesium	152	3.0	3.0
Thyroid, Porcine	7	2.9	2.9
Lamivudine	20	2.9	2.9
Oxybutynin	18	2.8	2.8
Conjugated Estrogens And Medroxyprogesterone Acetate	14	2.7	2.7
Paricalcitol	8	2.5	2.5
Dimethyl Fumarate	68	2.5	2.5
Azelastine	10	2.5	2.5
Fesoterodine Fumarate	6	2.5	2.5
Glimepiride	21	2.4	2.4
Natalizumab	96	2.4	2.4
Conjugated Estrogens	30	2.3	2.3
Acetaminophen And Codeine	6	2.2	2.2
Adalimumab	329	2.2	2.2
Cenobamate	4	2.1	2.1
Fluticasone Furoate And Vilanterol Trifenatate	17	2.1	2.1
Brinzolamide	4	2.1	2.1
Peginterferon Beta-1A	6	2.1	2.1
Lacosamide	17	2.0	2.1
Glecaprevir And Pibrentasvir	5	2.0	2.0
Somatropin	33	2.0	2.0
Linaclotide	12	2.0	2.0
Abaloparatide	13	2.0	2.0
Sodium Oxybate	29	2.0	2.0
Abatacept	60	2.0	2.0
Agalsidase Beta	4	1.9	1.9
Hydrocodone Bitartrate And Acetaminophen	24	1.9	1.9
Teriflunomide	19	1.9	1.9
Buprenorphine Hydrochloride, Naloxone Hydrochloride	10	1.9	1.9
Emicizumab	5	1.8	1.8
Ocrelizumab	25	1.8	1.8
Clozapine	50	1.8	1.8
Crizotinib	5	1.8	1.8
Insulin Lispro	54	1.8	1.8
Tofacitinib	71	1.7	1.7
Ranolazine	4	1.7	1.7
Vibegron	3	1.7	1.7
Patiromer	5	1.6	1.6
Diclofenac Potassium, Film Coated	3	1.6	1.6
Diclofenac Potassium Tablets	3	1.6	1.6
Sevelamer Carbonate	4	1.6	1.6
Selinexor	3	1.6	1.6
Etanercept	179	1.4	1.4
Isotretinoin	14	1.3	1.3
Methoxy Polyethylene Glycol-Epoetin Beta	3	1.2	1.2
Sarilumab	7	1.2	1.2
Ledipasvir And Sofosbuvir	5	1.2	1.2
Leuprolide Acetate	20	1.2	1.2
Glatiramer Acetate	15	1.1	1.1
Pimavanserin Tartrate	11	0.9	0.9
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	6	0.9	0.9
Droxidopa	4	0.8	0.8
Cinacalcet Hydrochloride	6	0.6	0.6
Adapalene	4	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.