Reaction

Hepatic Fibrosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,373 reports · 115 co-occurring drugs

As of the last recalculation, Hepatic Fibrosis appears in 3,373 FAERS reports alongside 115 co-occurring drug terms. The strongest observed disproportionality signal is ZIDOVUDINE (PRR 37.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Zidovudine	79	37.3	37.5
Lamivudine Oral	114	28.7	28.9
Lamivudine	130	27.0	27.1
Nevirapine	36	24.9	25.0
Efavirenz	44	24.7	24.8
Ursosiol	74	24.0	24.1
Ursodiol	77	22.3	22.4
Tenofovir Disoproxil Fumarate Tablets	24	17.3	17.3
Abacavir Sulfate	25	15.9	16.0
Entecavir	25	13.3	13.3
Leflunomide	210	13.1	13.2
Methadone Hydrochloride	21	12.0	12.1
Inclisiran	15	11.6	11.6
Methadone	78	11.5	11.5
Desoximetasone	34	11.1	11.1
Canagliflozin	51	10.7	10.7
Sirolimus	23	10.6	10.6
Nitrofurantoin	28	10.6	10.6
Nitrofurantoin (Monohydrate/Macrocrystals)	28	10.4	10.4
Sofosbuvir	32	10.1	10.1
Cholestyramine	18	9.2	9.2
Oxazepam	31	9.0	9.0
Ribavirin	89	8.7	8.8
Ethyl Alcohol	38	8.7	8.7
Mycophenilic Acid	29	8.7	8.7
Pegaspargase	17	8.6	8.6
Mercaptopurine	24	8.6	8.6
Basiliximab	16	8.4	8.4
Tacrolimus	200	8.3	8.3
Tacrolimus Ointment 0.1%	160	8.3	8.3
Tacrolimus Extended-Release Capsules	160	8.3	8.3
Methotrexate Sodium	550	8.1	8.2
Hydroxychloroquine	96	8.1	8.1
Amphotericin B	16	7.9	7.9
Methotrexate	468	7.8	7.8
Sulfasalazine	96	7.8	7.8
Mycophenolate Mofetil	160	7.6	7.6
Mycophenolate Mofetil Hydrochloride	160	7.6	7.6
Isopropyl Alcohol	40	7.4	7.4
Ado-Trastuzumab Emtansine	10	7.3	7.3
Tenofovir Disoproxil Fumarate	38	7.2	7.2
Azathioprine	96	6.9	6.9
Alcohol	42	6.7	6.8
Mycophenolic Acid	34	6.6	6.6
Fenofibrate	35	6.1	6.1
Gemfibrozil	15	6.1	6.1
Hydroxychloroquine Sulfate	86	6.0	6.0
Phytonadione	8	5.8	5.8
Ritonavir 100 Mg	14	5.8	5.8
Atazanavir	13	5.6	5.6
Cyclosporine	98	5.6	5.6
Ganciclovir	9	5.4	5.4
Metformin Hydrochloride	51	5.4	5.4
Metformin Hydrochloride Tablets	49	5.3	5.3
Metformin Hydrochloride Extended-Release Tablets	49	5.3	5.3
Metformin Hydrochloride Tablet	49	5.3	5.3
Oxaliplatin	63	5.3	5.3
Ganciclovir Sodium	9	5.3	5.3
Lumacaftor And Ivacaftor	7	5.0	5.1
Doxorubicin	71	5.0	5.0
Ritonavir	23	4.9	4.9
Terbinafine Hydrochloride	7	4.9	4.9
Vincristine Sulfate	23	4.9	4.9
Glyburide	19	4.9	4.9
Folic Acid	179	4.6	4.6
Peginterferon Alfa-2A	40	4.6	4.6
Anti-Thymocyte Globulin (Rabbit)	6	4.6	4.6
Ustekinumab	73	4.5	4.5
Everolimus Tablets	12	4.4	4.4
Venlafaxine	49	4.3	4.3
Adalimumab-Fkjp	31	4.2	4.2
Tocilizumab	74	4.1	4.1
Pyrazinamide	6	3.9	3.9
Ivacaftor	5	3.9	3.9
Leucovorin Calcium	12	3.9	3.9
Isoniazid	10	3.8	3.8
Fluorouracil Cream, 0.5%	46	3.8	3.8
Deferasirox	16	3.7	3.7
Fluorouracil	46	3.7	3.7
Rifampicin	6	3.7	3.7
Abatacept	78	3.5	3.5
Bosentan	28	3.4	3.4
Pancrelipase	21	3.4	3.4
Letrozole Tablets	26	3.4	3.4
Epoprostenol	7	3.3	3.3
Tofacitinib	96	3.3	3.3
Teduglutide	7	3.2	3.2
Panitumumab	8	3.2	3.2
Fludarabine Phosphate	20	3.2	3.2
Fosaprepitant Dimeglumine	7	3.1	3.1
Golimumab	42	3.0	3.0
Certolizumab Pegol	57	3.0	3.0
Cyclophosphamide Injection, Solution	85	3.0	3.0
Cyclophosphamide	85	3.0	3.0
Cyclophosphamide For Injection	85	3.0	3.0
Sevoflurane	4	3.0	3.0
Dofetilide	5	2.9	2.9
Icosapent Ethyl	4	2.9	2.9
Imatinib Mesylate	12	2.7	2.7
Secukinumab	67	2.6	2.6
Velpatasvir And Sofosbuvir	5	2.4	2.4
Apremilast	56	2.4	2.4
Temozolomide	8	2.3	2.3
Derma Foam Excel Hand Sanitizer	3	2.3	2.3
Ethanol	3	2.3	2.3
Glecaprevir And Pibrentasvir	4	2.2	2.2
Bosutinib	3	2.1	2.1
Gefitinib	3	2.1	2.1
Elexacaftor, Tezacaftor, And Ivacaftor	4	2.0	2.0
Rimegepant Sulfate	4	1.9	1.9
Ledipasvir And Sofosbuvir	6	1.9	1.9
Fam-Trastuzumab Deruxtecan-Nxki	3	1.8	1.8
Buprenorphine	24	1.6	1.6
Dornase Alfa	5	1.6	1.6
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	4	1.4	1.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.