Reaction

Personality Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,602 reports · 163 co-occurring drugs

As of the last recalculation, Personality Disorder appears in 2,602 FAERS reports alongside 163 co-occurring drug terms. The strongest observed disproportionality signal is METHYLPREDNISOLONE ACETATE (PRR 161.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methylprednisolone Acetate	152	161.2	164.3
Dimenhydrinate	172	138.2	140.4
Esomeprazole Magnesium Capsule, Delayed Release	158	92.7	93.7
Esomeprazole Magnesium Delayed Release Capsules	158	92.7	93.7
Esomeprazole Magnesium Dihydrate	158	92.3	93.3
Telmisartan	180	86.6	87.5
Irbesartan	304	61.5	61.9
Candesartan Cilexetil	164	53.2	53.5
Prochlorperazine	171	52.8	53.1
Diphenhydramine Hydrochloride Capsule, Liquid Filled	133	52.4	52.7
Cyanocobalamin	197	51.7	52.0
Rosuvastatin Calcium	152	45.8	46.0
Esomeprazole	296	43.0	43.2
Sitagliptin	301	37.6	37.8
Methylprednisolone Sodium Succinate	159	29.1	29.2
Antacid	162	29.0	29.1
Candesartan	117	27.4	27.5
Botulinum Toxin Type A	41	26.8	26.9
Calcium Carbonate	187	23.9	24.0
Lithium	65	21.1	21.2
Lithium Bromatum	65	21.1	21.2
Ezetimibe	177	20.2	20.2
Prochlorperazine Maleate	23	20.1	20.2
Metformin Hydrochloride Tablets	127	18.6	18.6
Metformin Hydrochloride Extended-Release Tablets	127	18.6	18.6
Metformin Hydrochloride Tablet	127	18.6	18.6
Pantoprazole Sodium In 0.9% Sodium Chloride	136	18.5	18.5
Pantoprazole Sodium Injection	136	18.5	18.5
Morphine	160	18.2	18.3
Metformin Hydrochloride	127	18.0	18.0
Valproate Sodium	45	17.7	17.7
Ziprasidone Mesylate	30	17.0	17.1
Zolpidem Tartrate	260	17.0	17.0
Asenapine Maleate	18	16.7	16.8
Lithium Carbonate	33	15.7	15.8
Doxepin Hydrochloride	24	15.3	15.4
Duloxetine Hydrochloride	310	14.8	14.9
Ustekinumab	175	14.6	14.6
Doxepin	18	14.3	14.3
Amlodipine Besylate	239	14.3	14.3
Olanzapine Pamoate	71	14.2	14.3
Sumatriptan Succinate	43	13.8	13.8
Bisoprolol Fumarate	216	13.8	13.8
Esomeprazole Magnesium	350	13.7	13.7
Paliperidone	39	13.6	13.6
Temazepam	62	13.5	13.5
Aripiprazole	190	13.3	13.3
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	239	13.1	13.1
Levothyroxine Sodium Anhydrous	154	13.0	13.0
Ondansetron Hydrochloride	176	12.2	12.3
Methylprednisolone	189	11.7	11.7
Hydrochlorothiazide	195	11.5	11.5
Insulin Lispro	186	11.5	11.5
Paroxetine Hydrochloride	125	11.5	11.5
Aripiprazole Oral	58	11.5	11.5
Aripiprazole Orally Disintegrating	58	11.5	11.5
Pregabalin	338	11.3	11.3
Lurasidone Hydrochloride	29	11.2	11.2
Varenicline Tartrate	104	10.8	10.8
Atorvastatin Calcium	293	10.6	10.6
Secukinumab	198	10.5	10.6
Ondansetron	135	10.4	10.4
Ondansetron Tablets	135	10.4	10.4
Venlafaxine Hydrochloride	158	10.1	10.1
Diphenhydramine Hydrochloride	194	10.0	10.0
Venlafaxine	87	10.0	10.0
Olanzapine	128	10.0	10.0
Diazepam Oral Solution (Concentrate)	105	9.8	9.8
Diazepam Oral	105	9.8	9.8
Morphine Sulfate	140	9.7	9.7
Lamotirigine	84	9.7	9.7
Lamotrigine Extended-Release	84	9.7	9.7
Lamotrigine Chewable Dispersible	84	9.7	9.7
Cyclobenzaprine	59	9.7	9.7
Ziprasidone	21	9.6	9.6
Acetylcysteine	11	9.4	9.4
Ramipril	137	9.3	9.3
Acetaminophen Tablet Extended Release	265	9.1	9.1
Pain Reliever	265	9.1	9.1
Acetaminophen 500Mg	265	9.1	9.1
Diazepam	131	9.0	9.0
Diclofenac	93	8.9	8.9
Atomoxetine Hydrochloride	26	8.8	8.8
Clonazepam	166	8.8	8.8
Metformin	345	8.8	8.8
Paroxetine Hydrochloride Hemihydrate	36	8.8	8.8
Naproxen	82	8.6	8.6
Paroxetine	36	8.6	8.6
Ezetimibe And Simvastatin	16	8.5	8.5
Quetiapine	187	8.3	8.3
Divalproex Sodium	47	8.2	8.2
Pantoprazole Sodium	144	8.2	8.2
Lamotrigine	126	8.0	8.0
Rituximab	195	7.9	7.9
Duloxetine	66	7.7	7.8
Phenytoin	20	7.7	7.7
Ethyl Alcohol	25	7.4	7.4
Diphenhydramine	57	7.4	7.4
Metformin Er 500 Mg	253	7.3	7.3
Metformin Er 750 Mg	253	7.3	7.3
Pantoprazole	215	7.3	7.3
Fluoxetine Hydrochloride	111	7.2	7.2
Phenobarbital	13	7.2	7.2
Mirtazapine	80	7.2	7.2
Topiramate	81	7.1	7.1
Guanfacine	7	7.1	7.1
Levothyroxine Sodium	256	7.1	7.1
Quetiapine Fumarate	26	7.1	7.1
Fluoxetine	57	7.0	7.0
Amlodipine Besylate And Benazepril Hydrochloride	8	6.9	7.0
Risperidone	111	6.9	6.9
Bupropion Hydrochloride	83	6.9	6.9
Trimethoprim	10	6.8	6.8
Citalopram Hydrobromide	88	6.8	6.8
Citalopram	110	6.7	6.7
Sertraline Hydrochloride	94	6.5	6.5
Insulin Glargine	188	6.5	6.5
Carbamazepine	53	6.4	6.4
Oxybutynin Chloride	7	6.4	6.4
Sumatriptan	30	6.4	6.4
Brexpiprazole	13	6.3	6.3
Tizanidine Hydrochloride	14	6.2	6.2
Isopropyl Alcohol	26	6.2	6.2
Oxcarbazepine	25	6.2	6.2
Amlodipine	193	6.1	6.1
Lisinopril	217	6.1	6.1
Vigabatrin	11	6.1	6.1
Oxazepam	16	6.0	6.0
Levodopa	9	6.0	6.0
Extended Phenytoin Sodium	12	5.8	5.8
Aspirin 325 Mg	328	5.7	5.7
Aspirin 81 Mg	328	5.7	5.7
Erenumab-Aooe	38	5.6	5.6
Baclofen	58	5.5	5.5
Alcohol	26	5.4	5.4
Diclofenac Sodium	98	5.4	5.4
Methylphenidate Hydrochloride	39	5.3	5.3
Haloperidol	16	5.3	5.3
Sertraline	75	5.2	5.2
Haloperidol Lactate	16	5.2	5.2
Vortioxetine	11	5.2	5.2
Levetiracetam	78	4.8	4.8
Ranitidine Hydrochloride	31	4.6	4.6
Paliperidone Palmitate	18	4.5	4.5
Vilazodone Hydrochloride	5	4.3	4.3
Clozapine	66	4.3	4.3
Levetiracetam In Sodium Chloride	40	4.2	4.2
Levetiracetam Oral	40	4.2	4.2
Levetiracetam Injection	40	4.2	4.2
Hydrocodone Bitartrate And Acetaminophen	29	4.2	4.2
Lisdexamfetamine Dimesylate	17	4.1	4.1
Lanreotide Acetate	4	4.1	4.1
Cenobamate	4	3.8	3.8
Brivaracetam	4	3.6	3.6
Lacosamide	16	3.5	3.5
Oxycodone Hydrochloride	91	3.4	3.4
Onabotulinumtoxina	32	3.3	3.3
Desvenlafaxine Succinate	11	3.3	3.3
Naltrexone	10	2.6	2.6
Drospirenone And Ethinyl Estradiol	13	2.4	2.4
Natalizumab	45	2.0	2.0
Esketamine Hydrochloride	3	1.3	1.3
Pimavanserin Tartrate	7	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.