Reaction

Ear Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,544 reports · 157 co-occurring drugs

As of the last recalculation, Ear Disorder appears in 4,544 FAERS reports alongside 157 co-occurring drug terms. The strongest observed disproportionality signal is VALPROATE SODIUM (PRR 15.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Valproate Sodium	69	15.5	15.6
Diphenhydramine Hydrochloride Capsule, Liquid Filled	49	10.6	10.6
Meclizine	33	9.3	9.3
Meclizine Hcl 12.5Mg	27	9.1	9.1
Meclizine Hcl 25Mg	27	9.1	9.1
Meclizine Hcl 12.5 Mg	27	9.1	9.1
Meclizine Hcl 25 Mg	27	9.1	9.1
Meclizine Hydrochloride	34	8.0	8.0
Human Immunoglobulin G	28	6.2	6.3
Indomethacin	18	6.2	6.3
Indapamide	24	6.2	6.2
Amlodipine Besylate And Valsartan	14	5.8	5.8
Mometasone Furoate	51	5.7	5.7
Infliximab-Dyyb	35	5.5	5.5
Avapritinib	14	5.3	5.3
Mometasone	20	5.0	5.0
Diphenhydramine Hcl	12	4.9	4.9
Phytonadione	9	4.9	4.9
Fluticasone Furoate	12	4.5	4.6
Felodipine Extended-Release Tablets	11	4.4	4.4
Felodipine	11	4.4	4.4
Azithromycin Dihydrate	56	4.4	4.4
Dofetilide	10	4.4	4.4
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	47	4.3	4.3
Zinc	23	4.3	4.3
Cimetidine	9	4.3	4.3
Zinc Chloride	23	4.3	4.3
Diphenhydramine	58	4.2	4.2
Fexofenadine Hydrochloride	20	4.2	4.2
Diphenhydramine Hydrochloride	149	4.2	4.2
Octreotide Acetate	28	4.2	4.2
Hydroxyzine Hydrochloride	12	4.2	4.2
Hydroxyzine Hydrochloride Oral	12	4.2	4.2
Rabeprazole	20	4.1	4.2
Tiotropium Bromide Inhalation Spray	10	4.1	4.1
Zinc Gluconate	23	4.0	4.0
Mepolizumab	43	4.0	4.0
Montelukast Sodium	103	3.9	3.9
Anastrozole Tablets	18	3.9	3.9
Moxifloxacin Hydrochloride	17	3.9	3.9
Adrenalinum	34	3.8	3.8
Ibuprofen Tablets, Coated	34	3.7	3.7
Ibuprofen Sodium	34	3.7	3.7
Levocetirizine Dihydrochloride	19	3.6	3.6
Fluticasone Propionate	101	3.6	3.6
Rizatriptan Benzoate	8	3.6	3.6
Azelastine	14	3.6	3.6
Cyclobenzaprine Hydrochloride	7	3.6	3.6
Sucralfate Oral	11	3.5	3.6
Sucralfate Oral Suspension	11	3.5	3.5
Epinephrine	50	3.5	3.5
Cetirizine Hcl	7	3.5	3.5
Latanoprost	38	3.5	3.5
Amlodipine Besylate And Benazepril Hydrochloride	7	3.5	3.5
Carboxymethylcellulose Sodium	7	3.4	3.4
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	15	3.3	3.3
Naproxen Sodium, Pseudoephedrine Hydrochloride	15	3.3	3.3
Adalimumab-Aaty	34	3.3	3.3
Brinzolamide	6	3.2	3.2
Niacin	8	3.2	3.2
Oxybutynin Chloride	6	3.1	3.1
Omalizumab	57	3.1	3.1
Adalimumab-Fkjp	31	3.1	3.1
Fexofenadine	11	3.1	3.1
Acalabrutinib	8	3.0	3.0
Fluticasone Propionate And Salmeterol Xinafoate	39	3.0	3.0
Prochlorperazine Maleate	6	3.0	3.0
Fexofenadine Hcl	6	3.0	3.0
Amikacin	11	3.0	3.0
Quinapril Hydrochloride	5	2.9	2.9
Etonogestrel And Ethinyl Estradiol	14	2.9	2.9
Anastrozole	23	2.9	2.9
Teriparatide	70	2.9	2.9
Budesonide And Formoterol Fumarate Dihydrate	60	2.9	2.9
Raloxifene Hydrochloride	9	2.8	2.8
Timolol Maleate	6	2.8	2.8
Secukinumab	96	2.8	2.8
Ticagrelor	19	2.7	2.7
Guaifenesin	18	2.7	2.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	5	2.7	2.7
Dexlansoprazole	24	2.6	2.6
Bosutinib	5	2.6	2.6
Rimegepant Sulfate	7	2.5	2.5
Phenobarbital	8	2.5	2.5
Tofacitinib	99	2.5	2.5
Selexipag	14	2.5	2.5
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	19	2.5	2.5
Epoprostenol	7	2.5	2.5
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	22	2.4	2.4
Riociguat	17	2.4	2.4
Cladribine	5	2.4	2.4
Benralizumab	10	2.3	2.3
Timolol	6	2.3	2.3
Tiotropium Bromide	67	2.3	2.3
Sodium Oxybate	32	2.2	2.2
Lurasidone Hydrochloride	10	2.2	2.2
Desoximetasone	9	2.2	2.2
Canakinumab	5	2.1	2.1
Niraparib	10	2.1	2.1
Teriflunomide	20	2.0	2.0
Palbociclib	42	2.0	2.0
Denosumab	87	2.0	2.0
Agalsidase Beta	4	2.0	2.0
Lifitegrast	7	2.0	2.0
Axitinib	8	1.9	1.9
Emicizumab	5	1.9	1.9
Dasatinib	15	1.9	1.9
Ocrelizumab	25	1.9	1.9
Asfotase Alfa	4	1.8	1.8
Abatacept	55	1.8	1.8
Golimumab	34	1.8	1.8
Pseudoephedrine Hydrochloride	4	1.8	1.8
Ambrisentan	48	1.8	1.8
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.8	1.8
Nintedanib	12	1.8	1.8
Ivacaftor	3	1.7	1.7
Varenicline Tartrate	30	1.7	1.7
Etanercept	220	1.7	1.7
Vibegron	3	1.7	1.7
Pseudoephedrine Hcl	4	1.7	1.7
Sofosbuvir	7	1.6	1.6
Fingolimod Hcl	30	1.6	1.6
Selinexor	3	1.6	1.6
Asenapine Maleate	3	1.6	1.6
Abaloparatide	10	1.6	1.6
Somatropin	24	1.5	1.5
Botulinum Toxin Type A	4	1.5	1.5
Risankizumab-Rzaa	25	1.4	1.4
Abemaciclib	6	1.4	1.4
Umeclidinium Bromide And Vilanterol Trifenatate	5	1.4	1.4
Ranolazine	3	1.3	1.3
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.3	1.3
Bimekizumab	6	1.3	1.3
Vigabatrin	4	1.3	1.3
Ixekizumab	10	1.2	1.2
Orlistat	7	1.2	1.2
Canagliflozin	8	1.2	1.2
Ranibizumab	7	1.2	1.2
Dornase Alfa	5	1.2	1.2
Diroximel Fumarate	3	1.2	1.2
Glatiramer Acetate	15	1.2	1.2
Dalfampridine	18	1.1	1.2
Pirfenidone	10	1.1	1.1
Isotretinoin	12	1.1	1.1
Brexpiprazole	4	1.1	1.1
Evolocumab	38	1.1	1.1
Pomalidomide	24	1.1	1.1
Lenalidomide	95	1.0	1.0
Nirmatrelvir And Ritonavir	12	1.0	1.0
Paliperidone Palmitate	7	1.0	1.0
Ledipasvir And Sofosbuvir	4	1.0	1.0
Alirocumab	5	0.9	0.9
Galcanezumab-Gnlm	6	0.9	0.9
Apremilast	25	0.8	0.8
Dupilumab	82	0.8	0.8
Guselkumab	5	0.6	0.6
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	4	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.