Reaction

Peripheral Ischaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,041 reports · 144 co-occurring drugs

As of the last recalculation, Peripheral Ischaemia appears in 4,041 FAERS reports alongside 144 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE BITARTRATE (PRR 48.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Norepinephrine Bitartrate	130	48.0	48.5
Norepinephrine	89	43.8	44.2
Heparin Sodium	68	25.9	26.0
Canagliflozin	109	19.3	19.3
Nilotinib	68	12.1	12.1
Gemcitabine Hydrochloride	115	11.5	11.5
Gemcitabine	79	10.5	10.5
Adrenalinum	82	10.4	10.4
Cisplatin	151	10.3	10.3
Pemetrexed	38	9.2	9.2
Pemetrexed Disodium	67	9.2	9.2
Alteplase	26	9.0	9.0
Epoetin Alfa	20	8.7	8.7
Quinine	13	7.8	7.8
Dalteparin Sodium	16	7.8	7.8
Cefepime	21	7.6	7.6
Ampicillin	12	7.5	7.5
Ampicillin Sodium	12	7.5	7.5
Epinephrine	93	7.5	7.5
Cefepime Hydrochloride	22	7.1	7.1
Tranexamic Acid	12	7.0	7.0
Cetuximab	42	7.0	7.0
Enoxaparin Sodium	74	6.7	6.7
Insulin	70	6.6	6.6
Clopidogrel	237	6.5	6.5
Oxaliplatin	91	6.4	6.4
Nitroglycerin	66	6.4	6.4
Digoxin	87	6.4	6.4
Clopidogrel Bisulfate	122	6.3	6.3
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	10	6.3	6.3
Chlorhexidine Gluconate	11	6.2	6.2
Meperidine Hydrochloride	11	6.2	6.2
Baricitinib	11	5.9	5.9
Nebivolol	18	5.8	5.8
Human Insulin	14	5.8	5.8
Sodium Bicarbonate	26	5.8	5.8
Sodium Bicarbonate Injection,	26	5.8	5.8
Magnesium Sulfate In Water For	14	5.7	5.7
Fosaprepitant Dimeglumine	15	5.6	5.6
Magnesium Sulfate Heptahydrate	14	5.6	5.6
Magnesium Sulfate	14	5.5	5.5
Testosterone	25	5.5	5.5
Dabigatran Etexilate	82	5.5	5.5
Romiplostim	16	5.5	5.5
Vancomycin	60	5.4	5.4
Vancomycin Hydrochloride	68	5.4	5.4
Dabigatran Etexilate Mesylate	74	5.3	5.3
Nifedipine	48	5.3	5.3
Piperacillin Sodium And Tazobactam Sodium	20	5.3	5.3
Capecitabine	90	5.2	5.2
Inclisiran	8	5.1	5.2
Cefazolin Sodium	12	5.1	5.1
Carboplatin	123	5.1	5.1
Bisoprolol Fumarate	129	5.0	5.0
Felodipine Extended-Release Tablets	11	5.0	5.0
Felodipine	11	5.0	5.0
Bupivacaine	9	5.0	5.0
Morphine	69	4.8	4.8
Aprepitant	17	4.8	4.8
Paricalcitol	13	4.8	4.8
Gentamicin	12	4.7	4.7
Lamivudine Oral	23	4.7	4.7
Gentamicin Sulfate	14	4.6	4.6
Propofol	32	4.5	4.5
Bleomycin Sulfate	9	4.5	4.5
Dapagliflozin	27	4.4	4.4
Sennosides 8.6 Mg Tablets	18	4.4	4.4
Senna	18	4.4	4.4
Bisacodyl Suppositories	11	4.4	4.4
Enalapril Maleate	21	4.4	4.4
Fluorouracil Cream, 0.5%	64	4.4	4.4
Atropine	7	4.4	4.4
Biscodyl	11	4.3	4.4
Rivaroxaban	170	4.3	4.4
Fluorouracil	64	4.3	4.3
Warfarin	103	4.3	4.3
Insulin Glargine-Yfgn	18	4.3	4.3
Bosentan	40	4.1	4.1
Rifampicin	8	4.1	4.1
Senna Leaf	18	4.0	4.0
Lamivudine	24	4.0	4.0
Cefazolin	7	4.0	4.0
Granisetron Hydrochloride	8	4.0	4.0
Epoprostenol	10	3.9	3.9
Granisetron	8	3.9	3.9
Dextrose	10	3.9	3.9
Warfarin Sodium	35	3.9	3.9
Ranibizumab	20	3.9	3.9
Dextrose Monohydrate	10	3.9	3.9
Fluticasone Furoate	9	3.8	3.8
Amphetamine	6	3.7	3.7
Atezolizumab	27	3.6	3.6
Doxazosin Mesylate	25	3.6	3.6
Imatinib	12	3.5	3.5
Doxazosin	19	3.5	3.5
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	21	3.5	3.5
Nicotine Polacrilex Mini	10	3.4	3.4
Nicotine Polarilex	10	3.4	3.4
Extended Phenytoin Sodium	11	3.4	3.4
Empagliflozin	44	3.4	3.4
Bumetanide	17	3.3	3.3
Tamsulosin Hydrochloride	13	3.3	3.3
Midazolam	16	3.3	3.3
Erythropoietin	13	3.3	3.3
Leucovorin Calcium	12	3.2	3.2
Erlotinib	6	3.2	3.2
Fondaparinux Sodium	5	3.2	3.2
Sevelamer Carbonate	7	3.1	3.1
Remdesivir	8	3.1	3.1
Darbepoetin Alfa	32	3.1	3.1
Bevacizumab	73	3.1	3.1
Pitavastatin Calcium	6	3.0	3.0
Apixaban	39	3.0	3.0
Dasatinib	21	2.9	2.9
Testosterone Cypionate	5	2.9	2.9
Linagliptin	10	2.8	2.8
Methoxy Polyethylene Glycol-Epoetin Beta	6	2.8	2.8
Insulin Human	20	2.6	2.6
Oseltamivir	4	2.6	2.6
Paclitaxel (Aibumin-Bound)	41	2.6	2.6
Thalidomide	18	2.5	2.5
Nivolumab	47	2.5	2.5
Sorafenib	10	2.5	2.5
Erlotinib Hydrochloride	6	2.5	2.5
Ranolazine	5	2.5	2.5
Docetaxel Anhydrous	30	2.3	2.3
Docetaxel	30	2.3	2.3
Ipilimumab	19	2.3	2.3
Ticagrelor	14	2.3	2.3
Paclitaxel	43	2.2	2.3
Pembrolizumab	45	2.2	2.2
Drospirenone And Ethinyl Estradiol	18	2.1	2.1
Durvalumab	8	2.0	2.0
Irinotecan Hydrochloride	5	2.0	2.0
Panitumumab	6	2.0	2.0
Daratumumab	14	1.8	1.8
Alpelisib	3	1.8	1.8
Bosutinib	3	1.7	1.7
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	1.7	1.7
Encorafenib	3	1.6	1.6
Cabozantinib	13	1.4	1.4
Emicizumab	3	1.3	1.3
Aflibercept	7	1.2	1.2
Cinacalcet Hydrochloride	9	1.0	1.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.