Reaction

Electrocardiogram Qrs Complex Prolonged reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,049 reports · 174 co-occurring drugs

As of the last recalculation, Electrocardiogram Qrs Complex Prolonged appears in 5,049 FAERS reports alongside 174 co-occurring drug terms. The strongest observed disproportionality signal is BUPROPION (PRR 45.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Bupropion	446	45.2	45.6
Norepinephrine	90	35.3	35.6
Norepinephrine Bitartrate	99	28.9	29.1
Loperamide Hydrochloride Oral	53	21.6	21.7
Lacosamide	184	21.1	21.2
Doxepin	49	20.1	20.2
Doxepin Hydrochloride	60	19.8	19.9
Sodium Bicarbonate	108	19.5	19.6
Sodium Bicarbonate Injection,	108	19.5	19.6
Lamotirigine	315	19.3	19.3
Lamotrigine Extended-Release	315	19.3	19.3
Lamotrigine Chewable Dispersible	315	19.3	19.3
Loperamide Hcl	54	17.5	17.5
Atropine	32	16.0	16.1
Ethyl Alcohol	98	15.1	15.2
Escitslopram	194	14.3	14.3
Atropine Sulfate	36	13.8	13.9
Alcohol	123	13.4	13.4
Derma Foam Excel Hand Sanitizer	25	13.0	13.0
Venlafaxine	216	12.9	13.0
Ethanol	25	12.9	12.9
Propofol	112	12.9	12.9
Fluoxetine	196	12.6	12.6
Propranolol Hydrochloride	210	12.5	12.5
Escitalopram Oxalate	209	12.3	12.3
Quetiapine Fumarate	86	12.2	12.2
Aripiprazole Oral	119	12.1	12.2
Aripiprazole Orally Disintegrating	119	12.1	12.2
Isopropyl Alcohol	96	11.9	11.9
Phenobarbital	41	11.8	11.8
Bupropion Hydrochloride	264	11.6	11.6
Midazolam Hydrochloride	74	11.5	11.5
Lamotrigine	333	11.1	11.1
Guanfacine	20	10.5	10.5
Amphetamine	21	10.5	10.5
Diphenhydramine Hcl	27	10.0	10.1
Midazolam	60	9.9	9.9
Amitriptyline Hydrochloride	38	9.0	9.0
Rocuronium Bromide	25	8.8	8.8
Citalopram Hydrobromide	217	8.7	8.7
Sevoflurane	17	8.5	8.5
Fesoterodine Fumarate	22	8.4	8.4
Benzonatate	33	8.3	8.3
Quetiapine	360	8.2	8.2
Fluoxetine Hydrochloride	243	8.2	8.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled	42	8.2	8.2
Adrenalinum	80	8.1	8.1
Clobazam	47	8.0	8.0
Hydroxyzine	90	7.9	7.9
Venlafaxine Hydrochloride	240	7.8	7.8
Lithium	47	7.7	7.8
Lithium Bromatum	47	7.7	7.8
Oxcarbazepine	58	7.4	7.4
Valproic Acid	55	7.3	7.3
Digoxin	121	7.1	7.1
Lithium Carbonate	29	7.1	7.1
Citalopram	225	7.0	7.1
Amiodarone Hydrochloride	19	7.0	7.0
Isosorbide Mononitrate	35	7.0	7.0
Levetiracetam In Sodium Chloride	127	6.9	6.9
Levetiracetam Oral	127	6.9	6.9
Levetiracetam Injection	127	6.9	6.9
Quinine	14	6.7	6.8
Sotalol Hydrochloride	27	6.7	6.7
Magnesium Sulfate Heptahydrate	21	6.7	6.7
Magnesium Sulfate	21	6.7	6.7
Escitalopram	218	6.6	6.7
Lidocaine Hydrochloride And Epinephrine	78	6.6	6.7
Lidicaine	77	6.6	6.6
Burn Relief	77	6.6	6.6
Polyethylene Glycol	17	6.5	6.5
Lidocaine, Menthol	77	6.5	6.5
Magnesium Sulfate In Water For	20	6.5	6.5
Hydroxychloroquine	113	6.4	6.4
Loperamide Hydrochloride	68	6.3	6.3
Methimazole	12	6.3	6.3
Lidocaine Hydrochloride And Epinephrine Bitartrate	78	6.1	6.1
Lidocaine Hydrochloride	87	6.0	6.0
Enalapril Maleate	36	6.0	6.0
Lidocaine 4%	78	6.0	6.0
Acetylcysteine	13	5.7	5.7
Lidocaine	78	5.6	5.6
Cimetidine	13	5.6	5.6
Phenytoin	28	5.6	5.6
Diazepam Oral Solution (Concentrate)	114	5.4	5.4
Diazepam Oral	114	5.4	5.4
Nicotine Polacrilex Mini	19	5.2	5.2
Nicotine Polarilex	19	5.2	5.2
Lorazepam	217	5.2	5.2
Epinephrine	80	5.1	5.1
Enalapril	68	5.1	5.1
Clonazepam	187	5.0	5.0
Captopril	11	4.7	4.7
Olanzapine	120	4.7	4.7
Clonidine	55	4.5	4.5
Aripiprazole	129	4.4	4.4
Diphenhydramine	67	4.4	4.4
Fentanyl Citrate	19	4.4	4.4
Dextrose	14	4.4	4.4
Diazepam	127	4.4	4.4
Dextrose Monohydrate	14	4.3	4.3
Oxazepam	22	4.2	4.2
Levetiracetam	133	4.2	4.2
Quinapril Hydrochloride	8	4.2	4.2
Tranexamic Acid	9	4.2	4.2
Carbamazepine	66	4.1	4.1
Methylphenidate	28	4.0	4.0
Cyclobenzaprine	48	4.0	4.0
Spironolactone	130	3.9	3.9
Methadone	40	3.9	3.9
Mirtazapine	85	3.9	3.9
Piperacillin And Tazobactam	12	3.9	3.9
Methylphenidate Hydrochloride	53	3.7	3.7
Trazodone Hydrochloride	14	3.7	3.7
Vortioxetine	15	3.6	3.6
Diltiazem Hydrochloride Extended-Release Tablets	10	3.6	3.6
Memantine	12	3.6	3.6
Memantine Hydrochloride	12	3.6	3.6
Diphenhydramine Hydrochloride	142	3.6	3.6
Bumetanide	23	3.6	3.6
Carisoprodol	16	3.5	3.5
Eszopiclone	21	3.4	3.4
Metoroprolol Tartrate	53	3.3	3.3
Meclizine Hcl 12.5Mg	11	3.3	3.3
Meclizine Hcl 25Mg	11	3.3	3.3
Meclizine Hcl 12.5 Mg	11	3.3	3.3
Meclizine Hcl 25 Mg	11	3.3	3.3
Ziprasidone	14	3.3	3.3
Melatonin	43	3.3	3.3
Raltegravir	13	3.3	3.3
Valsartan Oral	41	3.1	3.1
Torsemide	25	3.1	3.1
Nebivolol	12	3.1	3.1
Alprazolam	152	3.1	3.1
Metoprolol	183	3.0	3.0
Apixaban	49	3.0	3.0
Ibuprofen 200 Mg	142	3.0	3.0
Amlodipine	190	3.0	3.0
Ibuprofen Capsule	141	3.0	3.0
Ibuprofen Tablet, Film Coated	141	3.0	3.0
Ibupfrofen	141	3.0	3.0
Ibuprofen Tablets Usp, 200Mg	141	3.0	3.0
Ibuprofen Oral	141	3.0	3.0
Ibuprofen Capsules 200 Mg	141	3.0	3.0
Ibuprofen 200Mg	141	3.0	3.0
Piperacillin Sodium And Tazobactam Sodium	14	2.9	2.9
Vancomycin	41	2.9	2.9
Metoprolol Tartrate	189	2.9	2.9
Eplerenone	9	2.9	2.9
Metoprolol Tartrate Injection	130	2.9	2.9
Lisinopril And Hydrochlorothiazide	7	2.8	2.8
Tizanidine	16	2.8	2.8
Haloperidol	16	2.7	2.7
Vancomycin Hydrochloride	43	2.7	2.7
Haloperidol Lactate	16	2.7	2.7
Lisinopril And Hydrochlorothiazide Tablets	5	2.6	2.6
Sertraline	72	2.6	2.6
Piperacillin Sodium,Tazobactam Sodium	15	2.3	2.3
Nicotine Polacrilex	20	2.2	2.2
Nicotine	21	2.1	2.1
Metformin Hcl	28	2.1	2.1
Dronedarone	5	2.0	2.0
Risperidone	64	2.0	2.0
Dofetilide	5	2.0	2.0
Calcium, Magnesium, Potassium, And Sodium Oxybates	4	1.9	1.9
Patiromer	6	1.8	1.8
Tolvaptan	6	1.7	1.7
Remdesivir	5	1.5	1.5
Tafamidis	4	1.4	1.4
Cariprazine	3	1.3	1.3
Dabigatran Etexilate	25	1.3	1.3
Paliperidone	7	1.2	1.2
Cinacalcet Hydrochloride	5	0.4	0.4
Salicylic Acid	3	0.2	0.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.