Reaction

Fibrosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,036 reports · 158 co-occurring drugs

As of the last recalculation, Fibrosis appears in 3,036 FAERS reports alongside 158 co-occurring drug terms. The strongest observed disproportionality signal is EPOETIN ALFA (PRR 82.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Epoetin Alfa	136	82.4	83.3
Fesoterodine Fumarate	34	21.7	21.8
Fluticasone Furoate	35	20.0	20.1
Iron Sucrose	27	19.6	19.6
Paricalcitol	38	18.7	18.7
Risedronate Sodium	63	14.2	14.2
Amiodarone Hydrochloride	22	13.6	13.6
Temazepam	68	12.6	12.6
Erythropoietin	35	11.8	11.8
Docusate Sodium - Sennosides	52	11.2	11.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled	33	10.7	10.7
Sodium Bicarbonate	35	10.4	10.4
Sodium Bicarbonate Injection,	35	10.4	10.4
Hydroxychloroquine	108	10.2	10.3
Nintedanib	44	9.7	9.8
Antacid	62	9.1	9.1
Calcitriol Capsules 0.25 Mcg	26	9.0	9.0
Calcitriol Capsules 0.5 Mcg	26	9.0	9.0
Pirfenidone	52	8.9	8.9
Calcitriol	26	8.9	8.9
Quinine	11	8.8	8.8
Bleomycin Sulfate	13	8.7	8.7
Metoroprolol Tartrate	81	8.6	8.6
Diclofenac Sodium 1%	44	8.6	8.6
Diclofenac Sodium Topical	44	8.6	8.6
Diclofenac Sodium Topical Gel, 1%	44	8.5	8.5
Raloxifene Hydrochloride	18	8.5	8.5
Sofosbuvir	24	8.4	8.4
Diclofenac	100	8.2	8.2
Rosuvastatin Calcium	33	8.1	8.1
Tenofovir Disoproxil Fumarate Tablets	10	8.0	8.0
Ganciclovir Sodium	12	7.8	7.8
Darbepoetin Alfa	60	7.8	7.8
Vancomycin Hydrochloride	72	7.6	7.7
Enalapril Maleate	27	7.5	7.5
Docusate Sodium	62	7.5	7.5
Mycophenolate Mofetil	142	7.5	7.5
Mycophenolate Mofetil Hydrochloride	142	7.5	7.5
Ganciclovir	11	7.4	7.4
Romiplostim	16	7.3	7.3
Zinc	26	7.3	7.3
Zinc Chloride	26	7.2	7.2
Clonidine	52	7.1	7.1
Filgrastim	38	7.0	7.0
Zinc Gluconate	26	6.9	6.9
Faricimab	8	6.8	6.8
Calcium Carbonate	65	6.8	6.8
Metolazone	11	6.7	6.7
Valganciclovir	18	6.6	6.6
Valganciclovir Hydrochloride	18	6.6	6.6
Loratadine Oral	46	6.5	6.5
Basiliximab	11	6.4	6.4
Zidovudine	12	6.2	6.2
Diphenhydramine Hcl	10	6.2	6.2
Hydroxychloroquine Sulfate	80	6.2	6.2
Busulfan	14	6.1	6.1
Cinacalcet Hydrochloride	41	6.1	6.1
Lamivudine Oral	22	6.0	6.0
Anti-Thymocyte Globulin (Rabbit)	7	6.0	6.0
Lamivudine	26	5.8	5.8
Vancomycin	48	5.8	5.8
Ado-Trastuzumab Emtansine	7	5.7	5.7
Baricitinib	8	5.7	5.7
Eltrombopag Olamine	19	5.7	5.7
Glecaprevir And Pibrentasvir	9	5.6	5.6
Lopinavir And Ritonavir	11	5.6	5.6
Atenolol	105	5.6	5.6
Hydroxyurea	17	5.5	5.5
Emtricitabine And Tenofovir Alafenamide	9	5.5	5.5
Mycophenolic Acid	25	5.4	5.4
Ledipasvir And Sofosbuvir	15	5.4	5.4
Prednisolone Acetate	8	5.3	5.3
Escitslopram	44	5.2	5.3
Daptomycin	7	5.2	5.2
0Xygen	37	5.2	5.2
Oxygen	37	5.2	5.2
Carfilzomib	21	5.1	5.1
Diclofenac Sodium	109	5.1	5.1
Sirolimus	10	5.1	5.1
Acetaminophen And Codeine	9	5.1	5.1
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	114	5.0	5.0
Darunavir	11	5.0	5.0
Raltegravir	12	5.0	5.0
Ursosiol	14	5.0	5.0
Letrozole	44	5.0	5.0
Daspone	7	4.9	4.9
Piperacillin Sodium,Tazobactam Sodium	19	4.9	4.9
Dapsone Gel, 5%	7	4.9	4.9
Metoprolol Tartrate	186	4.9	4.9
Doxorubicin Hydrochloride	23	4.9	4.9
Nifedipine	33	4.8	4.8
Metoprolol	169	4.8	4.8
Ribavirin	44	4.7	4.7
Ritonavir	20	4.7	4.7
Tacrolimus	104	4.7	4.7
Mycophenilic Acid	14	4.6	4.7
Tobramycin Solution	8	4.6	4.6
Thalidomide	24	4.5	4.5
Dapsone	7	4.5	4.5
Cisplatin	50	4.4	4.4
Doxyclycline Hyclate	11	4.4	4.4
Tobramycin Sulfate	8	4.4	4.4
Ursodiol	14	4.4	4.4
Melphalan Hydrochloride	16	4.4	4.4
Venetoclax	39	4.4	4.4
Lithium	16	4.4	4.4
Lithium Bromatum	16	4.4	4.4
Efavirenz	7	4.3	4.3
Piperacillin And Tazobactam	8	4.3	4.3
Etoposide	45	4.2	4.2
Ifosfamide	13	4.2	4.2
Emtricitabine And Tenofovir Disoproxil Fumarate	27	4.1	4.1
Sulfasalazine	46	4.1	4.1
Panitumumab	9	3.9	3.9
Atazanavir	8	3.8	3.8
Dolutegravir Sodium	5	3.8	3.8
Abemaciclib	11	3.8	3.8
Azacitidine For	10	3.8	3.8
Ruxolitinib	39	3.8	3.8
Tobramycin	13	3.7	3.7
Azacitidine	16	3.7	3.7
Epoprostenol	7	3.7	3.7
Ranibizumab	14	3.6	3.6
Sevelamer Carbonate	6	3.6	3.6
Oxaliplatin	38	3.5	3.5
Entecavir	6	3.5	3.5
Fludarabine Phosphate	20	3.5	3.5
Etonogestrel	24	3.5	3.5
Cyclophosphamide Injection, Solution	85	3.4	3.4
Cyclophosphamide	85	3.4	3.4
Cyclophosphamide For Injection	85	3.4	3.4
Doxorubicin	41	3.2	3.2
Ranitidine Hydrochloride	25	3.2	3.2
Tenofovir Disoproxil Fumarate	15	3.1	3.1
Trastuzumab	31	3.1	3.1
Deferasirox	12	3.1	3.1
Fentanyl Citrate	8	3.1	3.1
Nevirapine	4	3.0	3.0
Capecitabine	40	3.0	3.0
Imatinib Mesylate	12	3.0	3.0
Peginterferon Alfa-2A	23	2.9	2.9
Alteplase	6	2.7	2.7
Minoxidil Foam 5% (Womens)	13	2.7	2.7
Velpatasvir And Sofosbuvir	5	2.7	2.7
Carboplatin	49	2.7	2.7
Ivacaftor	3	2.6	2.6
Erenumab-Aooe	20	2.5	2.5
Diclofenac Potassium, Film Coated	3	2.4	2.4
Diclofenac Potassium Tablets	3	2.4	2.4
Rucaparib	3	2.3	2.3
Agalsidase Beta	3	2.2	2.2
Crizotinib	4	2.2	2.2
Minoxidil	13	2.0	2.0
Daratumumab	11	1.9	1.9
Sarilumab	7	1.8	1.8
Aflibercept	7	1.5	1.5
Dornase Alfa	4	1.4	1.4
Copper	4	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.