Reaction

Goitre reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,057 reports · 158 co-occurring drugs

As of the last recalculation, Goitre appears in 4,057 FAERS reports alongside 158 co-occurring drug terms. The strongest observed disproportionality signal is METHIMAZOLE (PRR 33.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methimazole	50	33.1	33.3
Ketoprofen	49	19.4	19.5
Rosuvastatin Calcium	67	12.4	12.4
Alemtuzumab	45	12.1	12.1
Acetylcysteine	22	12.0	12.1
Thyroid, Porcine	24	11.6	11.6
Alendronate Sodium	202	10.8	10.8
Liothyronine Sodium	18	10.6	10.7
Amiodarone Hydrochloride	23	10.6	10.6
Lithium Carbonate	33	10.0	10.1
Exenatide	96	9.6	9.6
Lithium	46	9.5	9.5
Lithium Bromatum	46	9.5	9.5
Clindamycin	46	8.4	8.4
Epoprostenol	20	7.9	7.9
Valsartan Oral	81	7.8	7.8
Etonogestrel And Ethinyl Estradiol	33	7.7	7.7
Clindamycin Phosphate	49	7.6	7.6
Levothyroxine Sodium	420	7.5	7.5
Meclizine Hcl 12.5Mg	18	6.8	6.8
Meclizine Hcl 25Mg	18	6.8	6.8
Meclizine Hcl 12.5 Mg	18	6.8	6.8
Meclizine Hcl 25 Mg	18	6.8	6.8
Chlorhexidine Gluconate	12	6.8	6.8
Liraglutide	61	6.4	6.4
Indapamide	22	6.3	6.3
Lubiprostone	11	6.0	6.0
Torsemide	37	5.8	5.8
Tolterodine Tartrate	10	5.7	5.7
Dolutegravir Sodium	10	5.7	5.7
Candesartan Cilexetil	29	5.7	5.7
Meclizine	18	5.7	5.7
Valsartan	113	5.6	5.7
Irbesartan	48	5.6	5.6
Candesartan	38	5.5	5.5
Cephalexin	23	5.5	5.5
Fulvestrant	35	5.5	5.5
Levothyroxine Sodium Anhydrous	103	5.4	5.4
Glyburide	25	5.3	5.3
Ascorbic Acid	24	5.3	5.3
Valsartan And Hydrochlorothiazide	14	5.3	5.3
Gemfibrozil	15	5.1	5.1
Ezetimibe And Simvastatin	15	5.1	5.1
Ipratropium Bromide	35	5.1	5.1
Naproxen	76	5.0	5.0
Hyoscyamine Sulfate	9	5.0	5.0
Meperidine Hydrochloride	9	5.0	5.0
Sitagliptin And Metformin Hydrochloride	21	5.0	5.0
Amlodipine Besylate And Benazepril Hydrochloride	9	5.0	5.0
Meclizine Hydrochloride	19	5.0	5.0
Ribociclib	30	4.9	4.9
Losartan Potassium And Hydrochlorothiazide	11	4.9	4.9
Nebivolol	15	4.8	4.8
Octreotide Acetate	28	4.7	4.7
Promethazine Hydrochloride	17	4.7	4.7
Raloxifene Hydrochloride	13	4.6	4.6
Magnesium Hydroxide	12	4.6	4.6
Doxepin	9	4.6	4.6
Docusate Sodium - Sennosides	28	4.5	4.5
Darunavir	13	4.4	4.4
Temazepam	32	4.4	4.4
Benzonatate	14	4.4	4.4
Exemestane	18	4.3	4.3
Letrozole	51	4.3	4.3
Azithromycin Dihydrate	48	4.2	4.2
Salmeterol Xinafoate	7	4.2	4.2
Rabeprazole Sodium	22	4.2	4.2
Efavirenz	9	4.1	4.2
Sulfasalazine	62	4.1	4.1
Doxepin Hydrochloride	10	4.1	4.1
Terbinafine Hydrochloride	7	4.0	4.1
Carisoprodol	15	4.0	4.0
Chlorthalidone	9	4.0	4.0
Minocycline	9	4.0	4.0
Pioglitazone	33	3.9	3.9
Zinc Gluconate	20	3.9	3.9
Calcitriol Capsules 0.25 Mcg	15	3.8	3.9
Calcitriol Capsules 0.5 Mcg	15	3.8	3.9
Zidovudine	10	3.8	3.8
Dronabinol	6	3.8	3.8
Sitagliptin	53	3.8	3.8
Calcitriol	15	3.8	3.8
Interferon Beta-1B	14	3.8	3.8
Spironolactone	101	3.8	3.8
Amoxicillin	55	3.7	3.7
Olmesartan Medoxomil	26	3.7	3.7
Nilotinib	21	3.7	3.7
Lamivudine Oral	18	3.7	3.7
Metformin Hcl	39	3.6	3.6
Citalopram	95	3.6	3.6
Meloxicam	40	3.6	3.6
Citalopram Hydrobromide	73	3.5	3.5
Insulin Glulisine	7	3.5	3.5
Interferon Beta-1A	130	3.5	3.5
Lisinopril And Hydrochlorothiazide	7	3.5	3.5
Propranolol Hydrochloride	49	3.5	3.5
Oxybutynin Chloride	6	3.5	3.5
Hydroxychloroquine Sulfate	61	3.5	3.5
Mirabegron	26	3.5	3.5
Pravastatin Sodium	13	3.4	3.4
Ritonavir	19	3.3	3.3
Omeprazole	216	3.3	3.3
Lamivudine	20	3.3	3.3
Budesonide And Formoterol Fumarate Dihydrate	62	3.3	3.3
Estrogens, Conjugated	38	3.3	3.3
Conjugated Estrogens	37	3.3	3.3
Lanreotide Acetate	5	3.3	3.3
Lisinopril And Hydrochlorothiazide Tablets	5	3.3	3.3
Hydroxychloroquine	47	3.3	3.3
Fexofenadine	10	3.1	3.1
Conjugated Estrogens And Medroxyprogesterone Acetate	14	3.1	3.1
Ado-Trastuzumab Emtansine	5	3.0	3.0
Loratadine Oral	29	3.0	3.0
Bicalutamide	9	3.0	3.0
Tocilizumab	66	3.0	3.0
Letrozole Tablets	28	3.0	3.0
Estradiol	50	3.0	3.0
Amantadine	9	3.0	3.0
Oxybutynin	17	3.0	3.0
Glipizide	35	3.0	3.0
Granisetron Hydrochloride	6	3.0	3.0
Nebivolol Hydrochloride	19	2.9	2.9
Ibuprofen Sodium	24	2.9	2.9
Testosterone Cypionate	5	2.9	2.9
Pazopanib Hydrochloride	15	2.9	2.9
Insulin Aspart	36	2.8	2.8
Peginterferon Beta-1A	7	2.7	2.7
Cladribine	5	2.7	2.7
Loratadine And Pseudoephedrine Sulfate	4	2.6	2.6
Abatacept	68	2.5	2.5
Ipilimumab	21	2.5	2.5
Darbepoetin Alfa	26	2.5	2.5
Medroxyprogesterone Acetate	24	2.5	2.5
Pancrelipase	18	2.4	2.4
Bendamustine Hcl	7	2.3	2.3
Mepolizumab	22	2.3	2.3
Golimumab	36	2.2	2.2
Avapritinib	5	2.1	2.1
Tofacitinib	75	2.1	2.1
Romiplostim	6	2.0	2.0
Sodium Oxybate	26	2.0	2.0
Fentanyl Citrate	7	2.0	2.0
Oral Semaglutide	28	2.0	2.0
Bimatoprost	11	2.0	2.0
Asenapine Maleate	3	1.8	1.8
Certolizumab Pegol	39	1.7	1.7
Benralizumab	6	1.5	1.5
Romosozumab-Aqqg	4	1.5	1.5
Glatiramer Acetate	17	1.5	1.5
Natalizumab	51	1.4	1.4
Tirzepatide	45	1.4	1.4
Vigabatrin	4	1.4	1.4
Somatropin	19	1.3	1.3
Dulaglutide	21	1.2	1.2
Drospirenone And Ethinyl Estradiol	10	1.2	1.2
Guselkumab	7	1.0	1.0
Lifitegrast	3	0.9	0.9
Voxelotor	3	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.