Reaction

Premature Labour reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,631 reports · 140 co-occurring drugs

As of the last recalculation, Premature Labour appears in 5,631 FAERS reports alongside 140 co-occurring drug terms. The strongest observed disproportionality signal is METHADONE HYDROCHLORIDE (PRR 38.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methadone Hydrochloride	111	38.7	39.1
Zidovudine	107	30.1	30.4
Progesterone	156	25.9	26.1
Lopinavir And Ritonavir	91	25.2	25.4
Darunavir	100	24.9	25.0
Ritonavir	148	19.2	19.3
Ampicillin	41	18.4	18.5
Ampicillin Sodium	41	18.4	18.5
Magnesium Sulfate In Water For	57	16.7	16.7
Nevirapine	40	16.5	16.6
Magnesium Sulfate Heptahydrate	57	16.3	16.4
Raltegravir	72	16.3	16.4
Magnesium Sulfate	57	16.3	16.4
Labetalol	54	15.1	15.2
Ritonavir 100 Mg	58	14.5	14.5
Tenofovir Disoproxil Fumarate Tablets	28	12.0	12.1
Miconazole Nitrate	27	11.5	11.5
Atazanavir	42	10.9	10.9
Acetaminophen And Codeine	35	10.7	10.7
Nifedipine	130	10.4	10.4
Azathioprine	217	9.4	9.4
Indomethacin	32	9.0	9.0
Misoprostol	23	8.8	8.8
Lamivudine	72	8.7	8.7
Nicotine Polacrilex Mini	35	8.7	8.7
Nicotine Polarilex	35	8.7	8.7
Dalteparin Sodium	24	8.4	8.4
Butalbital, Acetaminophen, And Caffeine	24	8.4	8.4
Iron	143	8.1	8.1
Abacavir Sulfate	20	7.6	7.6
Rifampicin	19	7.0	7.0
Buprenorphine Hydrochloride, Naloxone Hydrochloride	43	6.6	6.6
Oseltamivir	14	6.5	6.5
Paroxetine Hydrochloride Hemihydrate	58	6.5	6.5
Emtricitabine And Tenofovir Disoproxil Fumarate	79	6.5	6.5
Paroxetine	58	6.4	6.4
Rizatriptan Benzoate	17	6.2	6.2
Lamivudine Oral	41	6.0	6.0
Pyrazinamide	15	5.9	5.9
Bleomycin Sulfate	16	5.7	5.7
Tenofovir Disoproxil Fumarate	50	5.6	5.6
Amitriptyline Hydrochloride	26	5.5	5.5
Infliximab	305	5.4	5.4
Oseltamivir Phosphate	34	5.2	5.2
Mesalamine	77	5.1	5.1
Folic Acid	323	5.0	5.0
Efavirenz	15	5.0	5.0
Bupivacaine	12	4.8	4.8
Promethazine Hydrochloride	23	4.6	4.6
Paroxetine Hydrochloride	111	4.6	4.6
Epoprostenol	16	4.5	4.5
Fluoxetine Hydrochloride	149	4.4	4.4
Enoxaparin Sodium	66	4.3	4.3
Acetaminophen, Aspirin (Nsaid) And Caffeine	19	4.1	4.1
Quetiapine Fumarate	32	4.0	4.0
Aripiprazole Oral	44	4.0	4.0
Aripiprazole Orally Disintegrating	44	4.0	4.0
Clobazam	26	4.0	4.0
Lamotrigine	138	3.9	3.9
Metoclopramide Hydrochloride	80	3.9	3.9
Diazepam Oral Solution (Concentrate)	91	3.8	3.8
Diazepam Oral	91	3.8	3.8
Cefazolin Sodium	12	3.7	3.7
Gentamicin	13	3.7	3.7
Nicotine	40	3.7	3.7
Cefazolin	9	3.7	3.7
Prednisolone	172	3.6	3.6
Prednisolone Oral	172	3.6	3.6
Prednisolone Oral Solution	172	3.6	3.6
Nicotine Polacrilex	37	3.6	3.6
Rifampin	14	3.6	3.6
Heparin Sodium	13	3.5	3.5
Metronidazole	60	3.5	3.5
Metoclopramide	51	3.5	3.5
Ursosiol	18	3.4	3.4
Insulin	51	3.4	3.4
Carbamazepine	61	3.4	3.4
Mirtazapine	83	3.4	3.4
Prochlorperazine	25	3.3	3.3
Acetaminophen, Aspirin, And Caffeine	19	3.3	3.3
Gentamicin Sulfate	14	3.3	3.3
Metronidazole Topical	42	3.3	3.3
Aripiprazole	105	3.2	3.2
Lactulose	33	3.2	3.2
Doxorubicin Hydrochloride	28	3.2	3.2
Erythromycin	16	3.2	3.2
Sevoflurane	7	3.1	3.1
Ifosfamide	18	3.1	3.1
Insulin Human	33	3.1	3.1
Diazepam	100	3.1	3.1
Ursodiol	18	3.1	3.1
Doxorubicin	73	3.1	3.1
Isoniazid	13	3.0	3.0
Insulin Glulisine	8	2.9	2.9
Rocuronium Bromide	9	2.8	2.8
Tacrolimus	117	2.8	2.8
Sumatriptan Succinate	19	2.8	2.8
Fondaparinux Sodium	6	2.7	2.7
Tramadol Hydrochloride	27	2.7	2.7
Lamotirigine	51	2.6	2.6
Lamotrigine Extended-Release	51	2.6	2.6
Lamotrigine Chewable Dispersible	51	2.6	2.6
Sertraline Hydrochloride	84	2.6	2.6
Propofol	26	2.6	2.6
Rimegepant Sulfate	9	2.6	2.6
Ceftriaxone Sodium	27	2.6	2.6
Phenobarbital	10	2.6	2.6
Isotretinoin	34	2.6	2.6
Ibuprofen And Diphenhydramine Citrate	16	2.5	2.5
Levetiracetam	91	2.5	2.5
Sumatriptan	26	2.5	2.5
Interferon Beta-1B	13	2.5	2.5
Topiramate	62	2.5	2.5
Diclofenac Sodium 1%	23	2.4	2.4
Diclofenac Sodium Topical	23	2.4	2.4
Diclofenac Sodium Topical Gel, 1%	23	2.4	2.4
Methadone	27	2.3	2.3
Iron Sucrose	6	2.3	2.3
Sildenafil Powder,	22	2.3	2.3
Interferon Beta-1A	115	2.2	2.2
Ranitidine	114	2.1	2.1
Imatinib Mesylate	16	2.1	2.1
Lurasidone Hydrochloride	11	1.9	1.9
Remdesivir	7	1.9	1.9
Ranitidine Hydrochloride	28	1.9	1.9
Ivacaftor	4	1.9	1.9
Drospirenone And Ethinyl Estradiol	22	1.8	1.8
Elexacaftor, Tezacaftor, And Ivacaftor	6	1.8	1.8
Ustekinumab	47	1.7	1.7
Copper	18	1.5	1.5
Insulin Lispro	54	1.4	1.4
Pegvaliase-Pqpz	3	1.4	1.4
Dornase Alfa	7	1.3	1.3
Levonorgestrel	71	1.3	1.3
Emtricitabine And Tenofovir Alafenamide	4	1.3	1.3
Glatiramer Acetate	19	1.2	1.2
Brexpiprazole	5	1.1	1.1
Onabotulinumtoxina	18	0.9	0.9
Orlistat	6	0.9	0.9
Natalizumab	42	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.