Reaction

Terminal State reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,622 reports · 129 co-occurring drugs

As of the last recalculation, Terminal State appears in 6,622 FAERS reports alongside 129 co-occurring drug terms. The strongest observed disproportionality signal is CANAKINUMAB (PRR 44.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Canakinumab	151	44.9	45.5
Anakinra	153	29.7	29.9
Leuprolide Acetate	641	28.7	28.9
Octreotide Acetate	231	24.5	24.7
Darbepoetin Alfa	318	19.4	19.5
Minocycline	69	18.8	18.9
Lanreotide Acetate	30	12.1	12.1
Denosumab	629	10.7	10.7
Pimavanserin Tartrate	178	10.4	10.4
Rivastigmine	61	10.3	10.3
Goserelin	36	8.5	8.5
Clozapine	289	7.5	7.5
Sulfasalazine	180	7.4	7.4
Bicalutamide	34	7.0	7.1
Trifluridine And Tipiracil	23	6.8	6.8
Epoprostenol	26	6.3	6.3
Bosentan	95	6.0	6.0
Hydroxychloroquine Sulfate	166	5.8	5.9
Hydroxychloroquine	135	5.8	5.8
Selexipag	46	5.6	5.6
Deferasirox	47	5.6	5.6
Carbidopa And Levodopa	82	5.5	5.5
Regorafenib	20	5.4	5.4
Macitentan	117	5.4	5.4
Tocilizumab	185	5.2	5.2
Leflunomide	166	5.1	5.1
Riociguat	52	5.0	5.1
Morphine	116	5.0	5.0
0Xygen	73	4.7	4.7
Oxygen	73	4.7	4.7
Levodopa	18	4.7	4.7
Rifaximin	30	4.5	4.5
Abatacept	183	4.2	4.2
Rasagiline Mesylate	15	4.2	4.2
Droxidopa	29	4.2	4.2
Ambrisentan	163	4.2	4.2
Everolimus	64	4.0	4.0
Enzalutamide	73	3.9	3.9
Pramipexole	19	3.9	3.9
Doxyclycline Hyclate	21	3.9	3.9
Valganciclovir Hydrochloride Powder,	15	3.9	3.9
Trimethoprim	14	3.7	3.7
Memantine	16	3.7	3.7
Memantine Hydrochloride	16	3.7	3.7
Treprostinil	133	3.4	3.4
Metolazone	12	3.4	3.4
Ropinirole	16	3.3	3.3
Rotigotine	15	3.3	3.3
Abiraterone	14	3.2	3.2
Ruxolitinib	73	3.2	3.2
Bisacodyl Suppositories	13	3.2	3.2
Romiplostim	15	3.1	3.1
Biscodyl	13	3.1	3.1
Bisacodyl	14	3.1	3.1
Sildenafil	57	3.1	3.1
Amantadine	15	3.1	3.1
Sildenafil Citrate	122	3.1	3.1
Oxycodone	178	3.0	3.0
Lactulose	36	3.0	3.0
Pazopanib Hydrochloride	25	2.9	2.9
Bumetanide	24	2.9	2.9
Dabrafenib	19	2.8	2.8
Valganciclovir	17	2.8	2.8
Valganciclovir Hydrochloride	17	2.8	2.8
Tadalafil	88	2.8	2.8
Infliximab	189	2.8	2.8
Donepezil Hydrochloride	32	2.7	2.8
Sildenafil Powder,	31	2.7	2.7
Dronabinol	7	2.7	2.7
Prochlorperazine Maleate	8	2.7	2.7
Sorafenib	18	2.7	2.7
Ranolazine	9	2.7	2.7
Pancrelipase	33	2.7	2.7
Melatonin	46	2.7	2.7
Rituximab	175	2.6	2.6
Midazolam	21	2.6	2.6
Hydroxyurea	17	2.5	2.5
Midazolam Hydrochloride	21	2.5	2.5
Cabozantinib	35	2.3	2.3
Tofacitinib	129	2.2	2.2
Fentanyl	69	2.2	2.2
Trametinib	17	2.2	2.2
Nintedanib	22	2.2	2.2
Imatinib Mesylate	19	2.1	2.1
Abiraterone Acetate	28	2.1	2.1
Niraparib	15	2.1	2.1
Budesonide, Glycopyrrolate, And Formoterol Fumarate	7	2.1	2.1
Ribociclib	21	2.1	2.1
Metoclopramide	36	2.1	2.1
Osimertinib	21	2.1	2.1
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	5	1.9	1.9
Sotalol Hydrochloride	10	1.9	1.9
Granisetron Hydrochloride	6	1.8	1.8
Alpelisib	5	1.8	1.8
Granisetron	6	1.8	1.8
Dofetilide	6	1.8	1.8
Rucaparib	5	1.8	1.8
Pirfenidone	23	1.8	1.8
Umeclidinium	5	1.8	1.8
Benralizumab	11	1.7	1.7
Olaparib	11	1.7	1.7
Tafamidis	6	1.6	1.6
Fluticasone Propionate And Salmeterol	21	1.6	1.6
Fluticasone Furoate And Vilanterol Trifenatate	18	1.6	1.6
Acalabrutinib	6	1.6	1.6
Venetoclax	30	1.5	1.5
Travoprost	4	1.5	1.5
Selinexor	4	1.5	1.5
Eculizumab	25	1.4	1.4
Tobramycin	11	1.4	1.4
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	14	1.4	1.4
Gefitinib	4	1.4	1.4
Eltrombopag Olamine	10	1.4	1.4
Diroximel Fumarate	5	1.3	1.3
Umeclidinium Bromide And Vilanterol Trifenatate	7	1.3	1.3
Lapatinib	6	1.2	1.2
Ranibizumab	10	1.2	1.2
Etanercept	218	1.1	1.1
Pegfilgrastim	36	1.1	1.1
Oxycodone Hydrochloride	77	1.1	1.1
Carfilzomib	10	1.1	1.1
Lumacaftor And Ivacaftor	3	1.1	1.1
Avapritinib	4	1.0	1.0
Romosozumab-Aqqg	4	0.9	0.9
Paliperidone Palmitate	9	0.9	0.9
Methoxy Polyethylene Glycol-Epoetin Beta	3	0.9	0.9
Ledipasvir And Sofosbuvir	5	0.8	0.8
Relugolix	5	0.7	0.7
Palivizumab	3	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.