Reaction

Mixed Liver Injury reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,873 reports · 128 co-occurring drugs

As of the last recalculation, Mixed Liver Injury appears in 2,873 FAERS reports alongside 128 co-occurring drug terms. The strongest observed disproportionality signal is AMOXICILLIN AND CLAVULANATE POTASSIUM (PRR 41.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Amoxicillin And Clavulanate Potassium	148	41.5	41.8
Atovaquone	39	35.6	35.7
Enoxaparin Sodium	205	27.7	27.8
Daptomycin	31	24.6	24.7
Piperacillin Sodium,Tazobactam Sodium	80	22.4	22.5
Ketoprofen	38	21.3	21.3
Cefepime Hydrochloride	41	18.7	18.7
Cefepime	35	17.9	17.9
Oxazepam	49	16.8	16.8
Voriconazole Injection	48	16.3	16.3
Meropenem	65	15.0	15.0
Heparin Sodium	27	14.3	14.4
Valacyclovir	80	14.3	14.3
Cefazolin Sodium	23	13.9	14.0
Sulfamethoxazole And Trimethoprim	153	13.8	13.8
Entecavir	21	13.1	13.1
Brentuximab Vedotin	18	12.8	12.8
Voriconazole	52	12.6	12.6
Pyrazinamide	16	12.4	12.4
Midazolam Hydrochloride	45	12.3	12.3
Amoxicillin	124	12.2	12.3
Ceftriaxone	54	12.1	12.2
Linezolid	49	12.1	12.1
Valganciclovir Hydrochloride Powder,	20	12.0	12.0
Lopinavir And Ritonavir	22	11.8	11.9
Febuxostat Tablets 40 Mg	16	11.5	11.5
Febuxostat Tablets 80 Mg	16	11.5	11.5
Piperacillin And Tazobactam	20	11.4	11.4
Midazolam	39	11.3	11.4
Ceftriaxone Sodium	58	11.2	11.2
Colchicine	38	10.6	10.6
Levofloxacin	85	10.5	10.5
Levofloxacin In 5% Dextrose	85	10.5	10.5
Propofol	51	10.3	10.3
Erythromycin	25	9.7	9.7
Micafungin Sodium	11	9.4	9.4
Amphotericin B	16	9.3	9.3
Iron Sucrose	12	9.2	9.2
Amitriptyline Hydrochloride	22	9.1	9.2
Valacyclovir Hydrochloride	84	8.9	8.9
Pemetrexed	26	8.9	8.9
Cefazolin	11	8.8	8.8
Rifampicin	12	8.6	8.6
Acetaminophen Tablet Extended Release	277	8.6	8.6
Pain Reliever	277	8.6	8.6
Acetaminophen 500Mg	277	8.6	8.6
Dronedarone	12	8.6	8.6
Ticagrelor	37	8.5	8.5
Rifampin	17	8.5	8.5
Pembrolizumab	117	8.4	8.4
Candesartan Cilexetil	29	8.1	8.1
Phenobarbital	16	8.0	8.0
Posaconazole Delayed-Release	12	7.9	8.0
Efavirenz	12	7.8	7.8
Piperacillin Sodium And Tazobactam Sodium	21	7.8	7.8
Hydroxyzine Hydrochloride	14	7.7	7.8
Hydroxyzine Hydrochloride Oral	14	7.7	7.8
Valganciclovir	20	7.7	7.7
Valganciclovir Hydrochloride	20	7.7	7.7
Instalax Polyethylene Glycol 3350	13	7.6	7.6
Posaconazole	17	7.6	7.6
Polyethylene Glycol 400	13	7.5	7.5
Ketoconazole Foam	15	7.4	7.4
Ketoconazole Cream, 2%	15	7.4	7.4
Iohexol	8	7.0	7.0
Febuxostat	16	6.9	7.0
Pemetrexed Disodium	36	6.9	6.9
Tramadol Hydrochloride	35	6.8	6.8
Isoniazid	15	6.7	6.7
Esomeprazole	56	6.7	6.7
Hydroxyurea	19	6.5	6.6
Trazodone Hydrochloride	14	6.5	6.5
Azacitidine For	16	6.4	6.4
Nebivolol	14	6.4	6.4
Lansoprazole	150	6.4	6.4
Ketoconazole	15	6.3	6.3
Azithromycin	34	6.2	6.2
Enalapril Maleate	21	6.2	6.2
Hydroxyzine	40	6.1	6.2
Gemcitabine Hydrochloride	44	6.1	6.1
Cladribine	8	6.0	6.0
Azithromycin Monohydrate	34	6.0	6.0
Gemcitabine	32	5.9	5.9
Irbesartan	36	5.9	5.9
Eplerenone	10	5.7	5.7
Umeclidinium Bromide And Vilanterol Trifenatate	13	5.7	5.7
Aprepitant	14	5.5	5.5
Pravastatin Sodium	15	5.5	5.5
Dorzolamide Hydrochloride And Timolol Maleate	6	5.5	5.5
Vancomycin	42	5.3	5.3
Obinutuzumab	12	5.3	5.3
Vancomycin Hydrochloride	47	5.2	5.2
Venlafaxine	50	5.1	5.1
Norepinephrine Bitartrate	10	5.0	5.0
Azacitidine	20	4.9	4.9
Terbinafine Hydrochloride	6	4.9	4.9
Allopurinol	101	4.8	4.8
Fesoterodine Fumarate	7	4.7	4.7
Metoclopramide	34	4.5	4.5
Anakinra	10	4.4	4.4
Nivolumab	57	4.3	4.3
Tafamidis	7	4.3	4.3
Levetiracetam In Sodium Chloride	45	4.3	4.3
Levetiracetam Oral	45	4.3	4.3
Amikacin	10	4.3	4.3
Levetiracetam Injection	45	4.3	4.3
Fosaprepitant Dimeglumine	8	4.2	4.2
Levetiracetam	74	4.1	4.1
Norepinephrine	6	4.1	4.1
Carboplatin	69	4.0	4.0
Raltegravir	9	4.0	4.0
Rocuronium Bromide	6	3.7	3.7
Paclitaxel (Aibumin-Bound)	41	3.7	3.7
Lacosamide	18	3.5	3.5
Bleomycin Sulfate	5	3.5	3.5
Temozolomide	9	3.1	3.1
Ifosfamide	9	3.0	3.0
Paclitaxel	41	3.0	3.0
Dapagliflozin	13	3.0	3.0
Abemaciclib	8	2.9	2.9
Ipilimumab	17	2.9	2.9
Interferon Beta-1B	7	2.6	2.7
Cenobamate	3	2.6	2.6
Durvalumab	7	2.5	2.5
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	6	2.4	2.4
Daratumumab	12	2.2	2.2
Atezolizumab	11	2.1	2.1
Nirmatrelvir And Ritonavir	9	1.2	1.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.