Reaction

Thrombotic Thrombocytopenic Purpura reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,486 reports · 118 co-occurring drugs

As of the last recalculation, Thrombotic Thrombocytopenic Purpura appears in 3,486 FAERS reports alongside 118 co-occurring drug terms. The strongest observed disproportionality signal is ACETYLCYSTEINE (PRR 18.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Acetylcysteine	29	18.5	18.6
Alemtuzumab	58	18.2	18.2
Prasugrel Hydrochloride	29	17.2	17.2
Clopidogrel	456	15.7	15.7
Carfilzomib	70	15.1	15.1
Gemcitabine	84	13.0	13.0
Gemcitabine Hydrochloride	110	12.7	12.8
Micafungin Sodium	17	12.0	12.0
Quinine	17	11.9	11.9
Terbinafine Hydrochloride	15	10.1	10.1
Valganciclovir Hydrochloride Powder,	20	9.8	9.9
Anti-Thymocyte Globulin (Rabbit)	13	9.7	9.7
Sirolimus	21	9.4	9.4
Captopril	15	9.4	9.4
Clopidogrel Bisulfate	152	9.2	9.2
Cyclosporine	148	8.3	8.3
Granisetron Hydrochloride	14	8.0	8.0
Mesna Injection	11	8.0	8.0
Mesna	11	7.8	7.8
Dexamethasone Sodium Phosphate	13	7.7	7.7
Granisetron	13	7.4	7.4
Valganciclovir	23	7.3	7.3
Valganciclovir Hydrochloride	23	7.3	7.3
Tacrolimus	179	7.1	7.1
Cefepime	17	7.1	7.1
Tacrolimus Ointment 0.1%	141	7.0	7.0
Tacrolimus Extended-Release Capsules	141	7.0	7.0
Tranexamic Acid	10	6.7	6.7
Methylprednisolone	146	6.5	6.5
Methylprednisolone Sodium Succinate	50	6.5	6.5
Busulfan	17	6.5	6.5
Cefepime Hydrochloride	17	6.3	6.3
Abacavir Sulfate	10	6.1	6.1
Bortezomib	85	5.8	5.8
Diclofenac Potassium, Film Coated	8	5.7	5.7
Diclofenac Potassium Tablets	8	5.7	5.7
Rituximab	192	5.7	5.7
Ciprofolxacin	66	5.6	5.6
Ciprofloxacin Tablets	66	5.6	5.6
Moxifloxacin	13	5.5	5.5
Voriconazole Injection	20	5.5	5.5
Mycophenilic Acid	19	5.5	5.5
Pemetrexed Disodium	34	5.4	5.4
Rifampin	13	5.3	5.3
Metronidazole Topical	42	5.3	5.3
Vancomycin Hydrochloride	57	5.2	5.2
Vancomycin	50	5.2	5.2
Eculizumab	47	5.2	5.2
Fludarabine Phosphate	34	5.2	5.2
Atovaquone	7	5.2	5.2
Dalteparin Sodium	9	5.1	5.1
Mycophenolic Acid	27	5.1	5.1
Oxaliplatin	62	5.1	5.1
Metronidazole	53	5.0	5.0
Mycophenolate Mofetil	110	5.0	5.0
Mycophenolate Mofetil Hydrochloride	110	5.0	5.0
Isoniazid	13	4.8	4.8
Voriconazole	24	4.7	4.7
Ifosfamide	17	4.7	4.7
Sunitinib Malate	31	4.7	4.7
Felodipine Extended-Release Tablets	9	4.7	4.7
Felodipine	9	4.7	4.7
Ticagrelor	25	4.7	4.7
Fluorouracil	60	4.7	4.7
Fluorouracil Cream, 0.5%	59	4.7	4.7
Panitumumab	12	4.6	4.6
Basiliximab	9	4.6	4.6
Ganciclovir Sodium	8	4.5	4.5
Bevacizumab	91	4.5	4.5
Quetiapine Fumarate	22	4.5	4.5
Diclofenac Potassium	8	4.4	4.4
Leucovorin Calcium	14	4.4	4.4
Thiotepa	7	4.4	4.4
Cisplatin	56	4.3	4.3
Cyclophosphamide Injection, Solution	124	4.3	4.3
Cyclophosphamide	124	4.3	4.3
Cyclophosphamide For Injection	124	4.3	4.3
Piperacillin And Tazobactam	9	4.2	4.2
Meropenem	22	4.1	4.1
Lithium	17	4.0	4.0
Lithium Bromatum	17	4.0	4.0
Phenytoin	14	4.0	4.0
Pemetrexed	14	3.9	3.9
Durvalumab	13	3.8	3.8
Posaconazole Delayed-Release	7	3.8	3.8
Norepinephrine	6	3.4	3.4
Carboplatin	70	3.3	3.3
Posaconazole	9	3.3	3.3
Dolutegravir Sodium	5	3.3	3.3
Thalidomide	20	3.3	3.3
Pyrazinamide	5	3.2	3.2
Romiplostim	8	3.2	3.2
Paclitaxel	52	3.2	3.2
Erlotinib	5	3.1	3.1
Paclitaxel (Aibumin-Bound)	40	2.9	2.9
Erlotinib Hydrochloride	6	2.9	2.9
Ado-Trastuzumab Emtansine	4	2.8	2.8
Doxorubicin Hydrochloride	15	2.8	2.8
Ipilimumab	19	2.6	2.6
Docetaxel Anhydrous	29	2.6	2.6
Docetaxel	29	2.6	2.6
Atezolizumab	16	2.5	2.5
Oseltamivir Phosphate	10	2.4	2.4
Peginterferon Alfa-2A	22	2.4	2.4
Tenofovir Disoproxil Fumarate	13	2.4	2.4
Ethyl Alcohol	10	2.2	2.2
Obinutuzumab	6	2.2	2.2
Pembrolizumab	37	2.1	2.1
Cetuximab	11	2.1	2.1
Nivolumab	32	2.0	2.0
Daratumumab	13	1.9	1.9
Pazopanib Hydrochloride	8	1.8	1.8
Pseudoephedrine Hydrochloride	3	1.7	1.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	1.6	1.6
Pseudoephedrine Hcl	3	1.6	1.6
Emtricitabine And Tenofovir Alafenamide	3	1.6	1.6
Ledipasvir And Sofosbuvir	5	1.6	1.6
Lenalidomide	90	1.3	1.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.