Reaction

Ammonia Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,035 reports · 151 co-occurring drugs

As of the last recalculation, Ammonia Increased appears in 5,035 FAERS reports alongside 151 co-occurring drug terms. The strongest observed disproportionality signal is RIFAXIMIN (PRR 202.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Rifaximin	852	202.2	210.8
Lactulose	648	80.0	81.4
Valproic Acid	227	31.1	31.4
Divalproex Sodium	322	30.5	30.7
Sorafenib	146	29.9	30.1
Lenvatinib	219	28.8	29.0
Valproate Sodium	99	20.2	20.3
Regorafenib	42	15.1	15.1
Phenobarbital	40	11.5	11.5
Spironolactone	362	11.4	11.4
Clobazam	65	11.1	11.2
Ursodiol	53	10.2	10.2
Pegaspargase	28	9.5	9.5
Ursosiol	43	9.2	9.2
Sofosbuvir	43	9.1	9.1
Ribavirin	135	8.9	8.9
Peginterferon Alfa-2A	109	8.5	8.5
Ledipasvir And Sofosbuvir	39	8.4	8.5
Phenytoin	41	8.2	8.2
Cannabidiol	43	7.7	7.7
Zonisamide	27	7.6	7.6
Vigabatrin	26	7.4	7.4
Topiramate	156	7.1	7.1
Oxcarbazepine	55	7.1	7.1
Deferasirox	43	6.8	6.8
Thiamine Hydrochloride	20	6.7	6.7
Velpatasvir And Sofosbuvir	20	6.5	6.5
Zinc	38	6.4	6.4
Zinc Gluconate	40	6.4	6.4
Zinc Chloride	38	6.4	6.4
Metolazone	17	6.3	6.3
Primidone	15	6.1	6.1
Carbamazepine	96	6.0	6.0
Bumetanide	38	6.0	6.0
Levetiracetam	182	5.8	5.8
Lacosamide	51	5.7	5.7
Derma Foam Excel Hand Sanitizer	11	5.7	5.7
Ethanol	11	5.7	5.7
Cenobamate	11	5.5	5.5
Propranolol Hydrochloride	93	5.4	5.4
Epoprostenol	17	5.4	5.4
Phytonadione	11	5.4	5.4
Furosemide	478	5.3	5.3
Levetiracetam In Sodium Chloride	98	5.3	5.3
Levetiracetam Oral	98	5.3	5.3
Levetiracetam Injection	98	5.3	5.3
Lithium	32	5.3	5.3
Lithium Bromatum	32	5.3	5.3
Extended Phenytoin Sodium	21	5.2	5.2
Magnesium Oxide	52	5.2	5.2
Promethazine Hydrochloride	22	4.9	4.9
Tolvaptan	17	4.8	4.9
Selexipag	30	4.8	4.8
Vincristine Sulfate	33	4.7	4.7
Macitentan	77	4.7	4.7
Levodopa	13	4.5	4.5
Insulin	59	4.4	4.4
Ferrous Sulfate	53	4.4	4.4
Sildenafil Powder,	37	4.3	4.3
Norepinephrine	11	4.3	4.3
Midazolam	25	4.1	4.1
Midazolam Hydrochloride	26	4.0	4.0
Acetylcysteine	9	4.0	4.0
Haloperidol	23	3.9	3.9
Haloperidol Lactate	23	3.9	3.9
Isoniazid	15	3.8	3.8
Potassium Chloride	104	3.8	3.8
Potassium Chloride, Dextrose Monohydrate	84	3.8	3.8
Potassium Chloride Oral	84	3.8	3.8
Potassium Chloride Extended-Release	84	3.8	3.8
Norepinephrine Bitartrate	13	3.7	3.7
Sildenafil	52	3.7	3.7
Cabozantinib	43	3.7	3.7
Rifampicin	9	3.7	3.7
Brivaracetam	8	3.7	3.7
Sucralfate	21	3.6	3.6
Iron	58	3.6	3.6
Pyrazinamide	8	3.5	3.5
Ziprasidone Mesylate	12	3.5	3.5
Vitamin E	26	3.4	3.4
Lithium Carbonate	14	3.4	3.4
Glecaprevir And Pibrentasvir	9	3.4	3.4
Ciprofloxacin Hydrochloride And Hydrocortisone	17	3.4	3.4
Mercaptopurine	14	3.3	3.3
Erythromycin	15	3.3	3.3
Ziprasidone	14	3.3	3.3
Lamotirigine	56	3.3	3.3
Torsemide	26	3.3	3.3
Lamotrigine Extended-Release	56	3.3	3.3
Lamotrigine Chewable Dispersible	56	3.3	3.3
Olanzapine Pamoate	32	3.2	3.2
Eltrombopag Olamine	18	3.2	3.2
Sildenafil Citrate	98	3.2	3.2
Sucralfate Oral	11	3.2	3.2
Sucralfate Oral Suspension	11	3.2	3.2
Propofol	28	3.2	3.2
Dextrose	10	3.1	3.1
Dextrose Monohydrate	10	3.1	3.1
Clonazepam	118	3.1	3.1
Cholestyramine	9	3.1	3.1
Multivitamin	37	3.1	3.1
Polyethylene Glycol	8	3.1	3.1
Benzonatate	12	3.0	3.0
Ado-Trastuzumab Emtansine	6	2.9	2.9
Lamotrigine	92	2.9	2.9
Tadalafil	70	2.9	2.9
Dicyclomine Hydrochloride	10	2.9	2.9
Olanzapine	74	2.9	2.9
Ambrisentan	85	2.8	2.8
Remdesivir	9	2.8	2.8
Zidovudine	9	2.8	2.8
Gefitinib	6	2.7	2.8
Bosentan	33	2.7	2.7
Prochlorperazine Maleate	6	2.7	2.7
Riociguat	21	2.7	2.7
Insulin Aspart	42	2.6	2.6
Fenofibrate	22	2.6	2.6
Iohexol	5	2.5	2.5
Entecavir	7	2.5	2.5
Dronedarone	6	2.4	2.4
Cytarabine	35	2.4	2.4
Prochlorperazine	16	2.4	2.4
Glimepiride	22	2.3	2.3
Treprostinil	69	2.3	2.3
Pancrelipase	21	2.3	2.3
Lapatinib	8	2.1	2.1
Glipizide	31	2.1	2.1
Lanreotide Acetate	4	2.1	2.1
Sunitinib Malate	19	2.0	2.0
Blinatumomab	5	2.0	2.0
Lurasidone Hydrochloride	10	2.0	2.0
Trifluridine And Tipiracil	5	1.9	1.9
Methadone Hydrochloride	5	1.9	1.9
Teduglutide	6	1.8	1.8
Nevirapine	4	1.8	1.8
Insulin Lispro	59	1.8	1.8
Insulin Glargine	101	1.7	1.7
Alcohol	16	1.7	1.7
Irinotecan Hydrochloride	5	1.6	1.6
Paliperidone	9	1.6	1.6
Naltrexone	11	1.5	1.5
Sevelamer Carbonate	4	1.4	1.4
Tafamidis	4	1.4	1.4
Daptomycin	3	1.3	1.3
Tenofovir Disoproxil Fumarate	9	1.1	1.1
Pimavanserin Tartrate	9	0.7	0.7
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.7	0.7
Paliperidone Palmitate	5	0.6	0.6
Cinacalcet Hydrochloride	7	0.6	0.6
Pomalidomide	15	0.6	0.6
Droxidopa	3	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.