Reaction

Cardiac Pacemaker Insertion reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,893 reports · 210 co-occurring drugs

As of the last recalculation, Cardiac Pacemaker Insertion appears in 5,893 FAERS reports alongside 210 co-occurring drug terms. The strongest observed disproportionality signal is RANOLAZINE (PRR 40.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ranolazine	116	40.0	40.5
Tafamidis	81	24.6	24.8
Bosentan	240	17.5	17.6
Dofetilide	50	16.9	17.0
Agalsidase Beta	34	13.1	13.1
Sotalol Hydrochloride	50	10.7	10.7
Valsartan And Hydrochlorothiazide	37	9.7	9.7
Macitentan	167	8.7	8.8
Digoxin	171	8.6	8.7
Selexipag	49	6.7	6.8
Sildenafil Powder,	67	6.7	6.7
Dronedarone	19	6.6	6.6
Ambrisentan	225	6.6	6.6
Dabigatran Etexilate Mesylate	127	6.3	6.3
Amiodarone Hydrochloride	19	6.0	6.0
Metolazone	19	6.0	6.0
Dabigatran Etexilate	127	5.9	5.9
Ibrutinib	128	5.7	5.7
Epoprostenol	21	5.7	5.7
Warfarin	198	5.7	5.7
Warfarin Sodium	73	5.6	5.6
Droxidopa	33	5.4	5.4
Torsemide	50	5.4	5.4
Prasugrel Hydrochloride	15	5.2	5.2
Enalapril Maleate	36	5.2	5.2
Riociguat	47	5.1	5.1
Amlodipine Besylate And Valsartan	16	5.1	5.1
Carvedilol	190	5.1	5.1
Isosorbide Dinitrate	28	5.1	5.1
Sildenafil	82	5.1	5.1
Tadalafil	139	5.0	5.0
Nitroglycerin	71	4.7	4.7
Fluticasone Propionate And Salmeterol	54	4.6	4.6
Rivastigmine	24	4.5	4.5
Relugolix	30	4.5	4.5
Insulin Human	50	4.5	4.5
Sildenafil Citrate	154	4.4	4.4
0Xygen	60	4.3	4.3
Oxygen	60	4.3	4.3
Cephalexin	26	4.3	4.3
Amlodipine Besylate And Benazepril Hydrochloride	11	4.2	4.2
Rivaroxaban	237	4.1	4.2
Glyburide	28	4.1	4.1
Diltiazem Hydrochloride	39	4.0	4.0
Human Insulin	14	4.0	4.0
Umeclidinium	10	3.9	4.0
Valsartan	115	3.9	3.9
Bumetanide	29	3.9	3.9
Eplerenone	14	3.9	3.9
Nintedanib	34	3.8	3.8
Potassium Chloride	122	3.8	3.8
Umeclidinium Bromide And Vilanterol Trifenatate	18	3.8	3.8
Furosemide	410	3.8	3.8
Alendronate Sodium	107	3.8	3.8
Potassium Chloride, Dextrose Monohydrate	97	3.7	3.7
Potassium Chloride Oral	97	3.7	3.7
Potassium Chloride Extended-Release	97	3.7	3.7
Ezetimibe And Simvastatin	16	3.7	3.7
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	43	3.7	3.7
Sitagliptin And Metformin Hydrochloride	22	3.6	3.6
Patiromer	14	3.6	3.6
Metoprolol Tartrate	266	3.6	3.6
Bicalutamide	15	3.5	3.5
Spironolactone	136	3.5	3.5
Hyoscyamine Sulfate	9	3.5	3.5
Fluticasone Furoate And Vilanterol Trifenatate	35	3.5	3.5
Clopidogrel	189	3.4	3.4
Donepezil Hydrochloride	35	3.4	3.4
Metoprolol Succinate	82	3.4	3.4
Metoroprolol Tartrate	62	3.3	3.3
Metoprolol	229	3.3	3.3
Metoprolol Succinate Er Tablets	57	3.2	3.2
Sucralfate Oral	13	3.2	3.2
Sucralfate Oral Suspension	13	3.2	3.2
Metoprolol Tartrate Injection	168	3.2	3.2
Apixaban	60	3.2	3.2
Docusate Sodium - Sennosides	29	3.2	3.2
Lovastatin	23	3.2	3.2
Tolterodine Tartrate	8	3.2	3.2
Atorvastatin Calcium	214	3.1	3.1
Meclizine Hcl 12.5Mg	12	3.1	3.1
Meclizine Hcl 25Mg	12	3.1	3.1
Meclizine Hcl 12.5 Mg	12	3.1	3.1
Meclizine Hcl 25 Mg	12	3.1	3.1
Glipizide	53	3.1	3.1
Alendronate Sodium Tablet	16	3.1	3.1
Losartan Potassium And Hydrochlorothiazide	10	3.0	3.0
Risankizumab-Rzaa	69	3.0	3.0
Enalapril	47	3.0	3.0
Losartan Potassium	66	3.0	3.0
Metformin Hcl	46	3.0	3.0
Teriparatide	93	2.9	2.9
Amlodipine Besylate	118	2.9	2.9
Aspirin	413	2.8	2.8
Aspirin 325 Mg	393	2.8	2.8
Aspirin 81 Mg	393	2.8	2.8
Terazosin Hydrochloride	7	2.8	2.8
Lisinopril And Hydrochlorothiazide	8	2.8	2.8
Lacosamide	29	2.8	2.8
Chlorthalidone	9	2.7	2.7
Meclizine Hydrochloride	15	2.7	2.7
Iron	51	2.7	2.7
Lisinopril And Hydrochlorothiazide Tablets	6	2.7	2.7
Quinapril Hydrochloride	6	2.7	2.7
Finasteride	45	2.6	2.6
Levodopa	9	2.6	2.6
Fluticasone Furoate	9	2.6	2.6
Lubiprostone	7	2.6	2.6
Ferrous Sulfate	37	2.6	2.6
Insulin	41	2.6	2.6
Meclizine	12	2.6	2.6
Gemfibrozil	11	2.6	2.6
Colchicine	19	2.6	2.6
Carbidopa And Levodopa	34	2.5	2.5
Alirocumab	18	2.5	2.5
Imatinib Mesylate	20	2.5	2.5
Pimavanserin Tartrate	39	2.5	2.5
Fenofibrate	25	2.5	2.5
Mepolizumab	35	2.5	2.5
Allopurinol	109	2.5	2.5
Empagliflozin	47	2.5	2.5
Primidone	7	2.4	2.4
Oxybutynin Chloride	6	2.4	2.4
Sitagliptin	49	2.4	2.4
Simvastatin	166	2.4	2.4
Darbepoetin Alfa	36	2.4	2.4
Benzonatate	11	2.4	2.4
Abiraterone	9	2.3	2.3
Losartan	112	2.3	2.3
Rosuvastatin	130	2.3	2.3
Glimepiride	25	2.3	2.3
Doxazosin Mesylate	23	2.3	2.3
Insulin Aspart	42	2.3	2.3
Dorzolamide Hydrochloride And Timolol Maleate	5	2.2	2.2
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	13	2.2	2.2
Naproxen Sodium, Pseudoephedrine Hydrochloride	13	2.2	2.2
Lisinopril	190	2.2	2.2
Rasagiline Mesylate	7	2.2	2.2
Isosorbide Mononitrate	13	2.2	2.2
Guaifenesin	19	2.2	2.2
Fluticasone Propionate And Salmeterol Xinafoate	37	2.2	2.2
Dutasteride	5	2.2	2.2
Ezetimibe	45	2.1	2.1
Linaclotide	16	2.1	2.1
Upadacitinib	48	2.1	2.1
Eszopiclone	15	2.1	2.1
Icosapent Ethyl	5	2.1	2.1
Memantine	8	2.1	2.1
Memantine Hydrochloride	8	2.1	2.1
Latanoprost	29	2.0	2.0
Doxazosin	16	2.0	2.0
Brivaracetam	5	2.0	2.0
Pioglitazone	24	2.0	2.0
Insulin Glargine	134	1.9	1.9
Linagliptin	10	1.9	1.9
Treprostinil	68	1.9	1.9
Iron Sucrose	5	1.9	1.9
Venetoclax	32	1.8	1.8
Multivitamin	26	1.8	1.8
Brimonidine Tartrate	9	1.8	1.8
Azelastine	9	1.8	1.8
Exenatide	26	1.7	1.7
Insulin Lispro	68	1.7	1.7
Pancrelipase	19	1.7	1.7
Insulin Glulisine	5	1.7	1.7
Ziprasidone Mesylate	7	1.7	1.7
Pitavastatin Calcium	5	1.7	1.7
Sodium Oxybate	31	1.7	1.7
Tiotropium Bromide	64	1.7	1.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	4	1.6	1.6
Travoprost	4	1.6	1.6
Brinzolamide	4	1.6	1.6
Bimatoprost	13	1.6	1.6
Testosterone Cypionate	4	1.6	1.6
Bosutinib	4	1.6	1.6
Romosozumab-Aqqg	6	1.6	1.6
Abiraterone Acetate	18	1.5	1.5
Apalutamide	5	1.5	1.5
Rotigotine	6	1.5	1.5
Evolocumab	67	1.5	1.5
Oral Semaglutide	29	1.4	1.4
Vibegron	3	1.3	1.3
Interferon Beta-1A	72	1.3	1.3
Interferon Beta-1B	7	1.3	1.3
Paricalcitol	5	1.3	1.3
Tolvaptan	5	1.2	1.2
Hydrocodone Bitartrate And Acetaminophen	19	1.2	1.2
Vismodegib	3	1.2	1.2
Avapritinib	4	1.2	1.2
Ledipasvir And Sofosbuvir	6	1.1	1.1
Denosumab	63	1.1	1.1
Enzalutamide	18	1.1	1.1
Peginterferon Beta-1A	4	1.1	1.1
Sofosbuvir	6	1.1	1.1
Sacubitril And Valsartan	35	1.1	1.1
Ranibizumab	8	1.1	1.1
Leuprolide Acetate	23	1.0	1.0
Ravulizumab	4	1.0	1.0
Pirfenidone	12	1.0	1.0
Aflibercept	9	1.0	1.0
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.0	1.0
Bimekizumab	6	1.0	1.0
Hydrocodone Bitartrate	12	1.0	1.0
Glecaprevir And Pibrentasvir	3	1.0	1.0
Cinacalcet Hydrochloride	12	0.9	0.9
Valbenazine	6	0.8	0.8
Velpatasvir And Sofosbuvir	3	0.8	0.8
Dupilumab	102	0.7	0.7
Guselkumab	5	0.5	0.5
Apremilast	19	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.