Reaction

Polydipsia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,908 reports · 130 co-occurring drugs

As of the last recalculation, Polydipsia appears in 3,908 FAERS reports alongside 130 co-occurring drug terms. The strongest observed disproportionality signal is TOLVAPTAN (PRR 80.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Tolvaptan	208	80.5	81.6
Lithium Carbonate	90	28.9	29.0
Olanzapine Pamoate	204	28.0	28.1
Alpelisib	35	21.6	21.7
Olanzapine	378	20.6	20.7
Haloperidol	71	15.8	15.9
Lithium	73	15.7	15.7
Lithium Bromatum	73	15.7	15.7
Haloperidol Lactate	71	15.5	15.6
Paliperidone	66	15.3	15.4
Atropine Sulfate	24	11.9	11.9
Asenapine Maleate	19	11.7	11.8
Ziprasidone	34	10.4	10.4
Risperidone	240	10.2	10.2
Ziprasidone Mesylate	27	10.1	10.2
Atropine	14	9.0	9.0
Quetiapine Fumarate	48	8.8	8.8
Lurasidone Hydrochloride	34	8.7	8.7
Thiamine Hydrochloride	20	8.6	8.6
Canagliflozin	47	8.5	8.5
Indapamide	28	8.4	8.4
Zonisamide	23	8.3	8.3
Empagliflozin	101	8.2	8.2
Lopinavir And Ritonavir	20	7.9	7.9
Aripiprazole Oral	58	7.6	7.6
Aripiprazole Orally Disintegrating	58	7.6	7.6
Dimenhydrinate	15	7.5	7.5
Abacavir Sulfate	13	7.1	7.1
Divalproex Sodium	61	7.1	7.1
Methocarbamol Tablets	22	7.0	7.0
Valproate Sodium	27	7.0	7.0
Oxcarbazepine	41	6.8	6.8
Sitagliptin And Metformin Hydrochloride	27	6.7	6.7
Quetiapine	229	6.7	6.7
Octreotide Acetate	38	6.7	6.7
Insulin Glargine-Yfgn	27	6.6	6.6
Aripiprazole	142	6.4	6.4
Methocarbamol	26	6.1	6.1
Cimetidine	11	6.1	6.1
Clozapine	137	6.0	6.0
Valproic Acid	35	6.0	6.0
Carbamazepine	73	5.9	5.9
Trimethoprim	13	5.9	5.9
Memantine	15	5.9	5.9
Memantine Hydrochloride	15	5.9	5.9
Escitslopram	63	5.8	5.9
Fluticasone Furoate	13	5.7	5.7
Quinine	9	5.6	5.6
Escitalopram Oxalate	75	5.6	5.6
Mirtazapine	90	5.3	5.3
Ritonavir	29	5.3	5.3
Raltegravir	16	5.2	5.2
Dapagliflozin	29	4.9	4.9
Metoclopramide	50	4.9	4.9
Brexpiprazole	15	4.8	4.8
Pegaspargase	11	4.8	4.8
Diphenhydramine Hcl	10	4.8	4.8
Glyburide	21	4.6	4.6
Chlorthalidone	10	4.6	4.6
Pyrazinamide	8	4.5	4.5
Lamotirigine	60	4.5	4.5
Lamotrigine Extended-Release	60	4.5	4.5
Lamotrigine Chewable Dispersible	60	4.5	4.5
Lacosamide	31	4.5	4.5
Lorazepam	143	4.4	4.4
Darunavir	12	4.2	4.2
Gemfibrozil	12	4.2	4.2
Bicalutamide	12	4.2	4.2
Insulin Glulisine	8	4.2	4.2
Metformin Hydrochloride	46	4.2	4.2
Paroxetine Hydrochloride	70	4.2	4.2
Zoledronic Acid	31	4.1	4.1
Duloxetine	53	4.1	4.1
Pioglitazone	33	4.1	4.1
Lactulose	29	4.1	4.1
Escitalopram	104	4.0	4.0
Metformin Er 500 Mg	214	4.0	4.0
Metformin Er 750 Mg	214	4.0	4.0
Metoclopramide Hydrochloride	56	3.9	3.9
Paliperidone Palmitate	23	3.8	3.8
Metformin	244	3.8	3.8
Icosapent Ethyl	6	3.8	3.8
Felodipine Extended-Release Tablets	8	3.7	3.7
Felodipine	8	3.7	3.7
Atazanavir	10	3.7	3.7
Lamotrigine	90	3.7	3.7
Travoprost	6	3.7	3.7
Rifampicin	7	3.7	3.7
Sertraline	80	3.7	3.7
Insulin Human	27	3.6	3.6
Isoniazid	11	3.6	3.6
Terazosin Hydrochloride	6	3.6	3.6
Ritonavir 100 Mg	10	3.6	3.6
Aprepitant	12	3.5	3.5
Tenofovir Disoproxil Fumarate	21	3.4	3.4
Guanfacine	5	3.4	3.4
Atomoxetine Hydrochloride	15	3.4	3.4
Varenicline Tartrate	50	3.4	3.4
Efavirenz	7	3.3	3.3
Lamivudine	19	3.3	3.3
Methylphenidate Hydrochloride	36	3.3	3.3
Doxazosin	17	3.2	3.2
Micafungin Sodium	5	3.1	3.1
Sitagliptin	42	3.1	3.1
Tenofovir Disoproxil Fumarate Tablets	5	3.1	3.1
Brivaracetam	5	3.0	3.0
Donepezil Hydrochloride	20	2.9	2.9
Fosaprepitant Dimeglumine	7	2.7	2.7
Asfotase Alfa	5	2.7	2.7
Levodopa	6	2.6	2.6
Lisdexamfetamine Dimesylate	16	2.6	2.6
Cenobamate	4	2.6	2.6
Armodafinil	10	2.5	2.5
Ribavirin	28	2.3	2.3
Insulin Lispro	55	2.1	2.1
Suvorexant	5	2.1	2.1
Loratadine And Pseudoephedrine Sulfate	3	2.0	2.0
Peginterferon Alfa-2A	20	2.0	2.0
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	1.9	1.9
Emtricitabine And Tenofovir Disoproxil Fumarate	16	1.9	1.9
Orlistat	9	1.9	1.9
Bosutinib	3	1.8	1.8
Naltrexone	10	1.7	1.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	1.5	1.5
Somatropin	18	1.3	1.3
Dulaglutide	19	1.1	1.1
Pegfilgrastim	17	0.9	0.9
Abaloparatide	5	0.9	0.9
Relugolix	4	0.9	0.9
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.