Reaction

Bruxism reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,327 reports · 201 co-occurring drugs

As of the last recalculation, Bruxism appears in 5,327 FAERS reports alongside 201 co-occurring drug terms. The strongest observed disproportionality signal is LURASIDONE HYDROCHLORIDE (PRR 20.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Lurasidone Hydrochloride	108	20.6	20.7
Ziprasidone	91	20.5	20.6
Calcium, Magnesium, Potassium, And Sodium Oxybates	42	19.2	19.3
Sertraline	451	16.3	16.4
Ziprasidone Mesylate	57	15.8	15.8
Cariprazine	37	15.6	15.7
Armodafinil	76	14.3	14.3
Lisdexamfetamine Dimesylate	116	14.0	14.1
Brexpiprazole	53	12.6	12.6
Sodium Oxybate	200	12.3	12.3
Vortioxetine	51	11.8	11.8
Lithium	75	11.8	11.8
Lithium Bromatum	75	11.8	11.8
Desvenlafaxine Succinate	70	10.3	10.3
Amphetamine	21	10.0	10.0
Citalopram Hydrobromide	260	9.9	9.9
Modafinil	77	9.4	9.5
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	84	9.4	9.4
Aripiprazole Oral	98	9.4	9.4
Aripiprazole Orally Disintegrating	98	9.4	9.4
Lithium Carbonate	40	9.3	9.3
Buspirone Hydrochloride	26	9.2	9.3
Aripiprazole	276	9.2	9.3
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	96	9.2	9.2
Methylphenidate Hydrochloride	131	8.8	8.8
Citalopram	294	8.8	8.8
Sertraline Hydrochloride	246	8.5	8.5
Valbenazine	48	7.5	7.5
Vilazodone Hydrochloride	17	7.2	7.2
Venlafaxine Hydrochloride	224	6.9	6.9
Clobazam	42	6.8	6.8
Fluoxetine	113	6.7	6.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	14	6.4	6.4
Fluoxetine Hydrochloride	203	6.4	6.4
Paliperidone	38	6.4	6.4
Duloxetine Hydrochloride	293	6.4	6.4
Bupropion Hydrochloride	157	6.4	6.4
Haloperidol Lactate	40	6.4	6.4
Haloperidol	39	6.3	6.3
Alendronate Sodium	155	6.2	6.2
Venlafaxine	109	6.0	6.1
Clonazepam	238	6.0	6.0
Carisoprodol	29	6.0	6.0
Escitalopram	207	6.0	6.0
Atomoxetine Hydrochloride	36	5.9	6.0
Asenapine Maleate	13	5.9	5.9
Metoclopramide	80	5.8	5.8
Metoclopramide Hydrochloride	111	5.7	5.7
Methylphenidate	42	5.7	5.7
Valproic Acid	45	5.6	5.6
Olanzapine Pamoate	58	5.6	5.6
Escitslopram	82	5.6	5.6
Paroxetine Hydrochloride	127	5.6	5.6
Escitalopram Oxalate	102	5.6	5.6
Propranolol Hydrochloride	99	5.4	5.5
Temazepam	51	5.3	5.3
Progesterone	31	5.3	5.3
Risedronate Sodium	40	5.1	5.1
Quetiapine	231	4.9	4.9
Fluticasone Furoate	15	4.8	4.9
Oxcarbazepine	40	4.8	4.8
Tretinoin	10	4.8	4.8
Lamotrigine	157	4.8	4.8
Trazodone Hydrochloride	19	4.8	4.8
Hyoscyamine Sulfate	11	4.7	4.7
Paliperidone Palmitate	38	4.6	4.6
Doxepin	12	4.6	4.6
Rizatriptan Benzoate	12	4.6	4.6
Diphenhydramine Hcl	13	4.6	4.6
Zonisamide	17	4.5	4.5
Clonidine	58	4.5	4.5
Methocarbamol Tablets	19	4.4	4.4
Thyroid, Porcine	12	4.4	4.4
Carbamazepine	74	4.4	4.4
Tolterodine Tartrate	10	4.4	4.4
Duloxetine	73	4.1	4.1
Liothyronine Sodium	9	4.0	4.0
Doxepin Hydrochloride	13	4.0	4.0
Guanfacine	8	4.0	4.0
Sumatriptan	37	3.8	3.8
Fexofenadine Hcl	9	3.8	3.8
Methocarbamol	22	3.8	3.8
Amantadine	15	3.8	3.8
Esomeprazole Magnesium Capsule, Delayed Release	14	3.8	3.8
Esomeprazole Magnesium Delayed Release Capsules	14	3.8	3.8
Esomeprazole Magnesium Dihydrate	14	3.8	3.8
Lamotirigine	68	3.7	3.7
Lamotrigine Extended-Release	68	3.7	3.7
Lamotrigine Chewable Dispersible	68	3.7	3.7
Risperidone	125	3.7	3.7
Buprenorphine Hydrochloride, Naloxone Hydrochloride	23	3.7	3.7
Diazepam	114	3.7	3.7
Divalproex Sodium	44	3.7	3.7
Paroxetine	32	3.7	3.7
Olanzapine	98	3.6	3.6
Quetiapine Fumarate	27	3.6	3.6
Sumatriptan Succinate	23	3.6	3.6
Eszopiclone	23	3.5	3.5
Melatonin	49	3.5	3.5
Paroxetine Hydrochloride Hemihydrate	30	3.5	3.5
Terbinafine Hydrochloride	8	3.5	3.5
Rasagiline Mesylate	10	3.5	3.5
Memantine	12	3.4	3.4
Memantine Hydrochloride	12	3.4	3.4
Valproate Sodium	18	3.4	3.4
Carbidopa And Levodopa	41	3.4	3.4
Diazepam Oral Solution (Concentrate)	76	3.4	3.4
Diazepam Oral	76	3.4	3.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	26	3.4	3.4
Niraparib	19	3.4	3.4
Montelukast Sodium	103	3.4	3.4
Bisacodyl Suppositories	11	3.3	3.3
Biscodyl	11	3.3	3.3
Extended Phenytoin Sodium	14	3.3	3.3
Cyclobenzaprine	41	3.2	3.2
Lorazepam	144	3.2	3.2
Amlodipine Besylate And Valsartan	9	3.2	3.2
Zinc	20	3.2	3.2
Ketoconazole	14	3.2	3.2
Baclofen	69	3.2	3.2
Zinc Chloride	20	3.2	3.2
Zinc Gluconate	21	3.1	3.1
Hydroxyzine	38	3.1	3.1
Naproxen	61	3.1	3.1
Bisacodyl	11	3.1	3.1
Cetiirizine	33	3.1	3.1
Cetirizine	59	3.0	3.0
Hydroxyzine Hydrochloride	10	3.0	3.0
Hydroxyzine Hydrochloride Oral	10	3.0	3.0
Alprazolam	153	3.0	3.0
Butalbital, Acetaminophen, And Caffeine	8	2.9	2.9
Mometasone Furoate	31	2.9	2.9
Bupropion	33	2.9	2.9
Nitrofurantoin	12	2.8	2.8
Mirtazapine	66	2.8	2.8
Gemfibrozil	11	2.8	2.8
Ezetimibe And Simvastatin	11	2.8	2.8
Nitrofurantoin (Monohydrate/Macrocrystals)	12	2.8	2.8
Pramipexole	11	2.8	2.8
Zolpidem Tartrate	96	2.8	2.8
Loratadine Oral	35	2.8	2.8
Micafungin Sodium	6	2.8	2.8
Cetirizine Hydrochloride Allergy	21	2.7	2.7
Cetirizine Hydrochloride Tablets	21	2.7	2.7
Fexofenadine Hydrochloride	15	2.7	2.7
Cetirizine Hydrochloride	109	2.6	2.6
Azelastine	12	2.6	2.6
Fexofenadine	11	2.6	2.6
Montelukast	54	2.5	2.5
Biotin	20	2.5	2.5
Rimegepant Sulfate	8	2.5	2.5
Vibegron	5	2.4	2.4
Multivitamin	31	2.4	2.4
Raloxifene Hydrochloride	9	2.4	2.4
Omalizumab	48	2.2	2.2
Estradiol	48	2.2	2.2
Loratadine	59	2.2	2.2
Vigabatrin	8	2.1	2.1
Estrogens, Conjugated	32	2.1	2.1
Suvorexant	7	2.1	2.1
Conjugated Estrogens	31	2.1	2.1
Onabotulinumtoxina	41	2.1	2.1
Carboxymethylcellulose Sodium	5	2.1	2.1
Naltrexone	16	2.0	2.0
Methadone	22	2.0	2.0
Tobramycin Solution	6	2.0	2.0
Hydrocodone Bitartrate And Acetaminophen	28	1.9	1.9
Tobramycin Sulfate	6	1.9	1.9
Cenobamate	4	1.9	1.9
Cannabidiol	11	1.8	1.8
Diclofenac Potassium	5	1.8	1.8
Fesoterodine Fumarate	5	1.8	1.8
Etonogestrel And Ethinyl Estradiol	10	1.8	1.8
Ethyl Alcohol	12	1.7	1.7
Acetaminophen, Aspirin, And Caffeine	9	1.7	1.7
Rotigotine	6	1.6	1.6
Levodopa	5	1.6	1.6
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	1.6	1.6
Pegaspargase	5	1.6	1.6
Botulinum Toxin Type A	5	1.6	1.6
Elexacaftor, Tezacaftor, And Ivacaftor	5	1.6	1.6
Varenicline Tartrate	32	1.6	1.6
Isopropyl Alcohol	13	1.5	1.5
Loratadine And Pseudoephedrine Sulfate	3	1.5	1.5
Diclofenac Potassium, Film Coated	3	1.4	1.4
Diclofenac Potassium Tablets	3	1.4	1.4
Clozapine	44	1.4	1.4
Dalfampridine	25	1.4	1.4
Fremanezumab-Vfrm	4	1.4	1.4
Denosumab	70	1.4	1.4
Oxycodone Hydrochloride	73	1.3	1.3
Esketamine Hydrochloride	6	1.3	1.3
Alcohol	13	1.3	1.3
Galcanezumab-Gnlm	10	1.2	1.2
Abaloparatide	9	1.2	1.2
Ledipasvir And Sofosbuvir	5	1.0	1.0
Buprenorphine	24	1.0	1.0
Romosozumab-Aqqg	3	0.9	0.9
Pimavanserin Tartrate	12	0.8	0.8
Dimethyl Fumarate	24	0.8	0.8
Droxidopa	3	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.