Reaction

Hepatitis B reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,985 reports · 159 co-occurring drugs

As of the last recalculation, Hepatitis B appears in 5,985 FAERS reports alongside 159 co-occurring drug terms. The strongest observed disproportionality signal is ENTECAVIR (PRR 103.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Entecavir	329	103.6	106.6
Tenofovir Disoproxil Fumarate Tablets	201	83.7	85.7
Lamivudine Oral	507	76.1	77.6
Lamivudine	587	73.1	74.6
Tenofovir Disoproxil Fumarate	312	34.6	34.9
Vincristine Sulfate	201	24.6	24.8
Doxorubicin Hydrochloride	216	23.8	24.0
Doxorubicin	544	23.3	23.4
Cyclophosphamide Injection, Solution	870	19.8	19.9
Cyclophosphamide	870	19.8	19.9
Cyclophosphamide For Injection	870	19.8	19.9
Bendamustine Hcl	83	18.9	19.0
Nevirapine	46	17.9	17.9
Rituximab	885	16.9	17.0
Polatuzumab Vedotin	42	15.1	15.1
Abacavir Sulfate	40	14.4	14.4
Efavirenz	45	14.1	14.2
Zidovudine	51	13.4	13.4
Prednisolone	617	13.1	13.2
Prednisolone Oral	617	13.1	13.2
Prednisolone Oral Solution	617	13.1	13.2
Melphalan	67	10.3	10.4
Ritonavir 100 Mg	44	10.3	10.3
Melphalan Hydrochloride	73	10.2	10.3
Fludarabine Phosphate	111	10.0	10.0
Bleomycin Sulfate	29	9.8	9.8
Darunavir	42	9.7	9.7
Cabotegravir	22	9.5	9.5
Sirolimus	36	9.3	9.4
Mesna	22	9.1	9.1
Anti-Thymocyte Globulin (Rabbit)	21	9.1	9.1
Basiliximab	30	8.9	8.9
Raltegravir	42	8.9	8.9
Dolutegravir Sodium	23	8.9	8.9
Mesna Injection	21	8.9	8.9
Ritonavir	73	8.8	8.8
Bendamustine Hydrochloride	30	8.8	8.8
Etoposide	170	8.2	8.3
Alemtuzumab	38	6.9	6.9
Atazanavir	28	6.8	6.8
Cytarabine	113	6.6	6.7
Obinutuzumab	31	6.6	6.6
Cisplatin	143	6.5	6.5
Ifosfamide	36	5.9	5.9
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	30	5.8	5.8
Daspone	16	5.7	5.7
Dapsone Gel, 5%	16	5.7	5.7
Lopinavir And Ritonavir	22	5.7	5.7
Bortezomib	141	5.6	5.6
Tacrolimus Ointment 0.1%	190	5.4	5.5
Cladribine	15	5.4	5.4
Tacrolimus Extended-Release Capsules	190	5.4	5.4
Sofosbuvir	30	5.3	5.3
Thalidomide	55	5.2	5.3
Dapsone	16	5.2	5.2
Tacrolimus	228	5.2	5.2
Isoniazid	24	5.2	5.2
Mycophenolate Mofetil	190	5.0	5.0
Mycophenolate Mofetil Hydrochloride	190	5.0	5.0
Cyclosporine	156	5.0	5.0
Human Immunoglobulin G	29	4.9	4.9
Ledipasvir And Sofosbuvir	26	4.7	4.7
Emtricitabine And Tenofovir Alafenamide	15	4.6	4.6
Methylprednisolone	175	4.5	4.5
Pyrazinamide	12	4.4	4.5
Everolimus Tablets	21	4.4	4.4
Gemcitabine	47	4.2	4.2
Hydrocortisone Sodium Succinate	11	4.1	4.1
Emtricitabine And Tenofovir Disoproxil Fumarate	53	4.1	4.1
Rabeprazole	25	3.9	3.9
Azathioprine	97	3.9	3.9
Sorafenib	23	3.9	3.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	11	3.8	3.8
Febuxostat Tablets 40 Mg	11	3.8	3.8
Febuxostat Tablets 80 Mg	11	3.8	3.8
Fluorouracil Cream, 0.5%	80	3.7	3.7
Prednisone	500	3.7	3.7
Fluorouracil	80	3.6	3.6
Gemcitabine Hydrochloride	55	3.6	3.6
Sulfamethoxazole And Trimethoprim	86	3.6	3.6
Adalimumab-Fkjp	46	3.5	3.5
Ursodiol	21	3.4	3.4
Imatinib	17	3.4	3.4
Valganciclovir	18	3.3	3.3
Valganciclovir Hydrochloride	18	3.3	3.3
Adalimumab-Aaty	45	3.3	3.3
Dexamethasone 1.5 Mg	269	3.3	3.3
Dexamethasone	269	3.3	3.3
Daratumumab	36	3.1	3.1
Valganciclovir Hydrochloride Powder,	11	3.1	3.1
Adalimumab-Adaz	45	3.0	3.0
Temozolomide	18	3.0	3.0
Anakinra	14	2.9	2.9
Ocrelizumab	52	2.9	2.9
Ursosiol	16	2.9	2.9
Mycophenilic Acid	17	2.9	2.9
Rifampicin	8	2.8	2.8
Dexamethasone Sodium Phosphate	8	2.7	2.7
Paroxetine Hydrochloride Hemihydrate	26	2.7	2.7
Valacyclovir	32	2.7	2.7
Paroxetine	26	2.7	2.7
Busulfan	12	2.7	2.7
Hydroxyurea	16	2.6	2.6
Ganciclovir Sodium	8	2.6	2.6
Imatinib Mesylate	21	2.6	2.6
Peginterferon Alfa-2A	39	2.5	2.5
Mycophenolic Acid	23	2.5	2.5
Sulfasalazine	55	2.5	2.5
Filgrastim	26	2.4	2.4
Ganciclovir	7	2.4	2.4
Acyclovir	77	2.4	2.4
Granisetron Hydrochloride	7	2.3	2.3
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	6	2.3	2.3
Methotrexate Sodium	312	2.3	2.3
Acalabrutinib	8	2.3	2.3
Febuxostat	11	2.3	2.3
Oxaliplatin	48	2.3	2.3
Valacyclovir Hydrochloride	45	2.2	2.2
Amphotericin B	8	2.2	2.2
Carfilzomib	18	2.2	2.2
Quinapril Hydrochloride	5	2.2	2.2
Atovaquone	5	2.2	2.2
Trastuzumab	42	2.1	2.1
Olanzapine Pamoate	25	2.1	2.1
Ofatumumab	20	2.1	2.1
Ibrutinib	46	2.0	2.0
Ribavirin	36	2.0	2.0
Velpatasvir And Sofosbuvir	7	1.9	1.9
Durvalumab	11	1.9	1.9
Golimumab	46	1.9	1.9
Osimertinib	17	1.8	1.8
Nilotinib	15	1.8	1.8
Venetoclax	31	1.8	1.8
Darbepoetin Alfa	27	1.7	1.7
Brentuximab Vedotin	5	1.7	1.7
Ustekinumab	49	1.7	1.7
Blinatumomab	5	1.7	1.7
Azacitidine	14	1.6	1.6
Atezolizumab	18	1.6	1.6
Lapatinib	7	1.6	1.6
Carboplatin	57	1.6	1.6
Docetaxel Anhydrous	28	1.4	1.4
Docetaxel	28	1.4	1.4
Paclitaxel (Aibumin-Bound)	32	1.4	1.4
Panitumumab	6	1.3	1.3
Peginterferon Beta-1A	5	1.3	1.3
Secukinumab	57	1.2	1.2
Abatacept	48	1.2	1.2
Hydrocodone Bitartrate And Acetaminophen	19	1.2	1.2
Siponimod	3	1.2	1.2
Romiplostim	5	1.2	1.2
Azacitidine For	6	1.1	1.1
Ixekizumab	12	1.1	1.1
Guselkumab	11	1.1	1.1
Remdesivir	4	1.0	1.0
Lenalidomide	116	1.0	1.0
Glecaprevir And Pibrentasvir	3	0.9	0.9
Pomalidomide	23	0.8	0.8
Apremilast	18	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.