Reaction

Vaginal Infection reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,650 reports · 149 co-occurring drugs

As of the last recalculation, Vaginal Infection appears in 4,650 FAERS reports alongside 149 co-occurring drug terms. The strongest observed disproportionality signal is COPPER (PRR 33.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Copper	302	33.5	33.7
Etonogestrel And Ethinyl Estradiol	90	18.5	18.6
Dimenhydrinate	33	14.0	14.0
Estradiol	240	13.1	13.1
Conjugated Estrogens	161	12.8	12.8
Estrogens, Conjugated	163	12.7	12.7
Infliximab-Dyyb	72	11.2	11.2
Clotrimazole	29	10.6	10.7
Drs. Clotrimazole	26	10.1	10.1
Family Wellness Clotrimazole	26	10.1	10.1
Clotrimazole Topical	26	10.1	10.1
Pramipexole	34	10.0	10.0
Levonorgestrel	359	8.6	8.6
Fluconazole	130	8.5	8.5
Ocrelizumab	112	8.3	8.3
Miconazole Nitrate	16	8.2	8.2
Canagliflozin	54	8.2	8.2
Naproxen	131	7.7	7.7
Docusate Sodium - Sennosides	53	7.4	7.4
Cyclobenzaprine	79	7.2	7.2
Metronidazole	98	7.0	7.0
Desoximetasone	28	6.6	6.6
Metronidazole Topical	68	6.5	6.5
Etonogestrel	67	6.4	6.4
Natalizumab	241	6.2	6.2
Estradiol Gel 0.1%	60	6.0	6.0
Estradiol Transdermal	60	6.0	6.0
Ciprofloxacin Hydrochloride And Hydrocortisone	27	5.8	5.8
Indomethacin	17	5.8	5.8
Nitrofurantoin (Monohydrate/Macrocrystals)	21	5.6	5.7
Naproxen Sodium Tablet, Coated	17	5.6	5.6
Naproxen Sodium, Coated Tablets	17	5.6	5.6
Naproxen Sodium 220Mg	17	5.6	5.6
Docusate Sodium	71	5.6	5.6
Clindamycin Phosphate	41	5.5	5.5
Nitrofurantoin	20	5.4	5.5
Hydrocortisone Sodium Succinate	11	5.2	5.3
Diphenhydramine	73	5.2	5.2
Diphenhydramine Hcl	13	5.2	5.2
Golimumab	98	5.2	5.2
Clindamycin	32	5.1	5.1
Hydrocortisone	99	5.1	5.1
Tretinoin	9	5.0	5.0
Methylprednisolone Sodium Succinate	50	4.9	4.9
Alendronate Sodium	107	4.8	4.8
Cephalexin	23	4.8	4.8
Salmeterol Xinafoate	9	4.7	4.7
Alemtuzumab	20	4.6	4.6
Liothyronine Sodium	9	4.6	4.6
Misoprostol	10	4.6	4.6
Naproxen Sodium	143	4.6	4.6
Prednisolone Acetate	10	4.3	4.3
Iron	64	4.3	4.3
Nystatin Ointment	25	4.3	4.3
Nystatin Cream	25	4.3	4.3
Nystatin	26	4.3	4.3
Mesalamine	53	4.3	4.3
Hydrocortisone Acetate	66	4.1	4.1
Anti-Itch	60	4.0	4.0
Anti-Pruritic	60	4.0	4.0
Antipruritic (Anti-Itch)	60	4.0	4.0
Cool Relief Gel With Aloe	60	4.0	4.0
Drs. Hydrocortisone	60	4.0	4.0
Hydrocortisone Continuous Spray	60	4.0	4.0
Hydrocortisone Spray	60	4.0	4.0
Anti-Itch Cream	60	4.0	4.0
Hydrocortisone Lotion	60	4.0	4.0
Hydrocortisone Cream 1%	60	4.0	4.0
Hydrocortisone Cream 1/2%	60	4.0	4.0
Hydrocortisone 1%	60	4.0	4.0
Hydrocortisone Cream	60	4.0	4.0
Temazepam	33	3.9	3.9
Progesterone	20	3.9	3.9
Diphenhydramine Hydrochloride	141	3.9	3.9
Diclofenac	73	3.8	3.8
Empagliflozin	57	3.8	3.8
Bisacodyl Suppositories	11	3.8	3.8
Pertuzumab	23	3.8	3.8
Dicyclomine Hydrochloride	12	3.8	3.8
Dexlansoprazole	35	3.8	3.8
Hydroxychloroquine Sulfate	75	3.7	3.7
Diclofenac Potassium, Film Coated	7	3.7	3.7
Diclofenac Potassium Tablets	7	3.7	3.7
Ciprofloxacin	75	3.7	3.7
Ciprofloxacin Hydrochloride	79	3.7	3.7
Meloxicam	47	3.6	3.7
Amoxicillin And Clavulanate Potassium	22	3.6	3.6
Doxycycline	54	3.6	3.6
Anastrozole	29	3.6	3.6
Doxycycline Hyclate	53	3.5	3.5
Moxifloxacin Hydrochloride	16	3.5	3.5
Moxifloxacin	11	3.5	3.5
Tocilizumab	88	3.5	3.5
Infliximab	165	3.5	3.5
Azithromycin Dihydrate	45	3.5	3.5
Doxyclycline Hyclate	13	3.4	3.4
Lidocaine	44	3.4	3.4
Oxybutynin	22	3.4	3.4
Methotrexate	298	3.3	3.3
Lubiprostone	7	3.3	3.3
Biotin	23	3.3	3.3
Cladribine	7	3.3	3.3
Amikacin	12	3.2	3.2
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	3.2	3.2
Ziprasidone Mesylate	10	3.1	3.1
Methotrexate Sodium	324	3.1	3.1
Ibuprofen And Diphenhydramine Citrate	16	3.1	3.1
Rizatriptan Benzoate	7	3.1	3.1
Hydroxyzine Hydrochloride	9	3.1	3.1
Hydroxyzine Hydrochloride Oral	9	3.1	3.1
Adrenalinum	28	3.0	3.0
Secukinumab	107	3.0	3.0
Baclofen	56	2.9	2.9
Diclofenac Potassium	7	2.9	2.9
Diclofenac Sodium	95	2.9	2.9
Ofatumumab	21	2.8	2.8
Valacyclovir Hydrochloride	44	2.8	2.8
Ziprasidone	11	2.8	2.8
Baricitinib	6	2.8	2.8
Dapagliflozin	19	2.7	2.7
Medroxyprogesterone Acetate	30	2.7	2.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	20	2.5	2.5
Vedolizumab	48	2.5	2.5
Sitagliptin And Metformin Hydrochloride	12	2.5	2.5
Sumatriptan	21	2.5	2.5
Vilazodone Hydrochloride	5	2.4	2.4
Fingolimod Hcl	45	2.3	2.3
Fesoterodine Fumarate	5	2.1	2.1
Siponimod	4	2.0	2.0
Certolizumab Pegol	52	2.0	2.0
Hydromorphone Hydrochloride	40	2.0	2.0
Drospirenone And Ethinyl Estradiol	19	1.9	1.9
Conjugated Estrogens And Medroxyprogesterone Acetate	10	1.9	1.9
Bimekizumab	9	1.9	1.9
Abatacept	58	1.9	1.9
Interferon Beta-1A	74	1.7	1.7
Teriflunomide	17	1.7	1.7
Tofacitinib	69	1.7	1.7
Glatiramer Acetate	21	1.6	1.6
Voclosporin	3	1.5	1.5
Dalfampridine	24	1.5	1.5
Avapritinib	4	1.5	1.5
Etanercept	189	1.4	1.4
Leuprolide Acetate	23	1.3	1.3
Exenatide	15	1.3	1.3
Patiromer	3	1.0	1.0
Hydrocodone Bitartrate	9	0.9	0.9
Dulaglutide	18	0.9	0.9
Adapalene	4	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.