Reaction

Periorbital Oedema reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,120 reports · 132 co-occurring drugs

As of the last recalculation, Periorbital Oedema appears in 5,120 FAERS reports alongside 132 co-occurring drug terms. The strongest observed disproportionality signal is AVAPRITINIB (PRR 61.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Avapritinib	178	61.9	62.8
Imatinib Mesylate	249	38.1	38.4
Imatinib	141	33.4	33.7
Sevoflurane	23	11.3	11.3
Diclofenac	226	11.1	11.1
Botulinum Toxin Type A	30	9.9	9.9
Sunitinib Malate	84	8.8	8.8
Diclofenac Sodium	298	8.5	8.5
Terbinafine Hydrochloride	18	8.3	8.3
Tranexamic Acid	18	8.3	8.3
Progesterone	42	7.5	7.5
Propofol	62	7.0	7.0
Dasatinib	60	6.6	6.6
Onabotulinumtoxina	120	6.4	6.5
Pemetrexed	33	6.3	6.3
Atropine Sulfate	16	6.0	6.0
Tobramycin Sulfate	18	5.9	5.9
Atropine	12	5.9	5.9
Rocuronium Bromide	17	5.9	5.9
Pemetrexed Disodium	54	5.8	5.8
Tobramycin Solution	17	5.8	5.8
Amitriptyline Hydrochloride	24	5.6	5.6
Amoxicillin	102	5.5	5.5
Indapamide	24	5.5	5.5
Bosutinib	12	5.4	5.4
Cefazolin	12	5.4	5.4
Chlorhexidine Gluconate	12	5.3	5.4
Cefazolin Sodium	15	5.1	5.1
Haloperidol	28	4.7	4.7
Iron Sucrose	11	4.7	4.7
Dorzolamide Hydrochloride And Timolol Maleate	9	4.6	4.6
Haloperidol Lactate	28	4.6	4.6
Amphotericin B	14	4.6	4.6
Itraconazole	13	4.5	4.5
Ibuprofen 200Mg	211	4.4	4.4
Ibuprofen Capsule	210	4.4	4.4
Ibuprofen Tablet, Film Coated	210	4.4	4.4
Ibupfrofen	210	4.4	4.4
Ibuprofen Tablets Usp, 200Mg	210	4.4	4.4
Ibuprofen Oral	210	4.4	4.4
Iohexol	9	4.4	4.4
Ibuprofen Capsules 200 Mg	210	4.4	4.4
Ibuprofen 200 Mg	210	4.4	4.4
Doxazosin	30	4.4	4.4
Doxazosin Mesylate	38	4.3	4.3
Phenytoin	22	4.3	4.3
Thiamine Hydrochloride	13	4.3	4.3
Liothyronine Sodium	9	4.2	4.2
Quinapril Hydrochloride	8	4.1	4.1
Oseltamivir	8	4.1	4.1
Loratadine Oral	49	4.1	4.1
Sirolimus	13	3.9	3.9
Cefuroxime	11	3.9	3.9
Granisetron Hydrochloride	10	3.9	3.9
Granisetron	10	3.9	3.9
Nilotinib	28	3.9	3.9
Midazolam Hydrochloride	25	3.8	3.8
Melphalan Hydrochloride	23	3.7	3.7
Ibuprofen	241	3.7	3.7
Posaconazole Delayed-Release	10	3.7	3.7
Naproxen Sodium Tablet, Coated	12	3.6	3.6
Naproxen Sodium, Coated Tablets	12	3.6	3.6
Naproxen	69	3.6	3.6
Naproxen Sodium 220Mg	12	3.6	3.6
Midazolam	22	3.6	3.6
Diclofenac Sodium 1%	31	3.5	3.5
Diclofenac Sodium Topical	31	3.5	3.5
Diclofenac Sodium Topical Gel, 1%	31	3.5	3.5
Daptomycin	8	3.5	3.5
Valproic Acid	27	3.5	3.5
Octreotide Acetate	26	3.5	3.5
Nitrofurantoin	14	3.5	3.5
Vancomycin Hydrochloride	55	3.4	3.4
Nitrofurantoin (Monohydrate/Macrocrystals)	14	3.4	3.4
Melphalan	19	3.4	3.4
Vancomycin	48	3.4	3.4
Filgrastim	31	3.4	3.4
Enalapril Maleate	20	3.3	3.3
Timolol Maleate	8	3.3	3.3
Ceftriaxone	26	3.2	3.2
Loratadine Tablet	42	3.2	3.2
Budesonide	46	3.2	3.2
Loperamide Hydrochloride Oral	8	3.2	3.2
Minoxidil Foam 5% (Womens)	25	3.1	3.1
Metronidazole Topical	36	3.1	3.1
Ceftriaxone Sodium	29	3.1	3.1
Agalsidase Beta	7	3.1	3.1
Vemurafenib	9	3.0	3.0
Pegaspargase	9	3.0	3.0
Efavirenz	8	2.9	2.9
Tobramycin	17	2.9	2.9
Loratadine	75	2.9	2.9
Voriconazole Injection	15	2.8	2.8
Omalizumab	57	2.7	2.7
Valsartan And Hydrochlorothiazide	9	2.7	2.7
Hydroxyurea	14	2.7	2.7
Busulfan	10	2.6	2.6
Loperamide Hcl	8	2.5	2.5
Estradiol Gel 0.1%	28	2.5	2.5
Estradiol Transdermal	28	2.5	2.5
Posaconazole	10	2.5	2.5
Oseltamivir Phosphate	15	2.5	2.5
Epinephrine	40	2.5	2.5
Oxazepam	13	2.5	2.5
Mesna Injection	5	2.5	2.5
Piperacillin Sodium,Tazobactam Sodium	16	2.5	2.5
Minoxidil	27	2.5	2.5
Latanoprost	30	2.4	2.4
Mesna	5	2.4	2.4
Ado-Trastuzumab Emtansine	5	2.4	2.4
Memantine	8	2.4	2.4
Memantine Hydrochloride	8	2.4	2.4
Brinzolamide	5	2.3	2.3
Bupivacaine	5	2.2	2.2
Thiotepa	5	2.1	2.1
Fentanyl Citrate	9	2.0	2.0
Cenobamate	4	1.9	1.9
Carboplatin	60	1.9	1.9
Bortezomib	41	1.9	1.9
Bimatoprost	13	1.8	1.8
Cetuximab	12	1.6	1.6
Loratadine And Pseudoephedrine Sulfate	3	1.5	1.5
Methoxy Polyethylene Glycol-Epoetin Beta	4	1.5	1.5
Paricalcitol	5	1.4	1.4
Cenegermin-Bkbj	4	1.3	1.3
Crizotinib	4	1.3	1.3
Sofosbuvir	6	1.2	1.2
Encorafenib	3	1.2	1.2
Orlistat	7	1.1	1.1
Lifitegrast	4	1.0	1.0
Pegfilgrastim	17	0.7	0.7
Voxelotor	3	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.