Reaction

Blood Chloride Decreased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,566 reports · 173 co-occurring drugs

As of the last recalculation, Blood Chloride Decreased appears in 2,566 FAERS reports alongside 173 co-occurring drug terms. The strongest observed disproportionality signal is METOLAZONE (PRR 21.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Metolazone	29	21.2	21.2
Fosaprepitant Dimeglumine	20	11.9	11.9
Ado-Trastuzumab Emtansine	12	11.6	11.6
Magnesium Sulfate In Water For	18	11.5	11.5
Magnesium Sulfate Heptahydrate	18	11.3	11.3
Magnesium Sulfate	18	11.3	11.3
Tolterodine Tartrate	12	10.9	10.9
Oxcarbazepine	42	10.6	10.7
Aprepitant	24	10.6	10.6
Quinine	11	10.4	10.5
Cisplatin	96	10.3	10.3
Potassium Chloride, Dextrose Monohydrate	111	10.1	10.1
Potassium Chloride Oral	111	10.1	10.1
Tolvaptan	18	10.1	10.1
Potassium Chloride Extended-Release	111	10.1	10.1
Telmisartan	22	10.1	10.1
Sucralfate Oral	17	9.8	9.8
Sucralfate Oral Suspension	17	9.7	9.7
Potassium Chloride	129	9.6	9.6
Docusate Sodium 100Mg	28	9.6	9.6
Ciprofloxacin Hydrochloride And Hydrocortisone	24	9.4	9.4
Digoxin	81	9.4	9.4
Linagliptin	21	9.4	9.4
Losartan Potassium And Hydrochlorothiazide	13	9.1	9.1
Standardized Senna Concentrate	14	9.1	9.1
Carisoprodol	21	9.0	9.0
Asfotase Alfa	11	8.9	8.9
Enalapril Maleate	27	8.9	8.9
Cefazolin Sodium	13	8.8	8.8
Sucralfate	25	8.5	8.5
Risedronate Sodium	32	8.4	8.5
Valsartan And Hydrochlorothiazide	14	8.4	8.4
Isosorbide Dinitrate	20	8.4	8.4
Ketoconazole Foam	15	8.3	8.3
Polyethylene Glycol	11	8.3	8.3
Ketoconazole Cream, 2%	15	8.2	8.2
Nystatin Ointment	26	8.1	8.1
Nystatin Cream	26	8.1	8.1
Nystatin	27	8.1	8.1
Gemfibrozil	15	8.1	8.1
Bumetanide	26	8.1	8.1
Dextrose	13	8.0	8.1
Lisinopril And Hydrochlorothiazide	10	8.0	8.0
Amlodipine Besylate And Benazepril Hydrochloride	9	7.9	7.9
Dextrose Monohydrate	13	7.9	7.9
Theophylline Anhydrous	12	7.9	7.9
Magnesium Oxide	40	7.9	7.9
Olanzapine Pamoate	39	7.8	7.8
Erythromycin	18	7.8	7.8
Theophylline	11	7.8	7.8
Octreotide Acetate	29	7.8	7.8
Indapamide	17	7.7	7.7
Ipratropium Bromide	33	7.6	7.6
Sodium Chloride Tablet	67	7.6	7.6
Sodium Chloride Tablets	67	7.6	7.6
Ketoconazole	16	7.5	7.5
Sodium Chloride	70	7.4	7.4
Fluconazole	62	7.3	7.3
Clotrimazole	11	7.3	7.3
Docusate Sodium	51	7.3	7.3
Magnesium Hydroxide	12	7.3	7.3
Mupirocin	12	7.2	7.3
Moxifloxacin Hydrochloride	18	7.2	7.3
Pemetrexed	19	7.2	7.2
Nitroglycerin	47	7.2	7.2
Dexamethasone Sodium Phosphate	9	7.2	7.2
Cephalexin	19	7.2	7.2
Oseltamivir	7	7.1	7.2
Mupirocin Calcium	12	7.1	7.1
Prochlorperazine	24	7.1	7.1
Drs. Clotrimazole	10	7.0	7.0
Family Wellness Clotrimazole	10	7.0	7.0
Clotrimazole Topical	10	7.0	7.0
Hydrochlorothiazide	119	6.9	6.9
Warfarin Sodium	39	6.9	6.9
Epoetin Alfa	10	6.9	6.9
Calcium Gluconate	10	6.8	6.8
Niraparib	18	6.6	6.6
Metoclopramide Hydrochloride	61	6.5	6.5
Colchicine	21	6.5	6.5
Oxybutynin Chloride	7	6.5	6.5
Rizatriptan Benzoate	8	6.4	6.4
Metoroprolol Tartrate	51	6.4	6.4
Paliperidone	18	6.3	6.3
Furosemide	282	6.3	6.3
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	23	6.2	6.2
Dorzolamide Hydrochloride And Timolol Maleate	6	6.2	6.2
Enalapril	41	6.1	6.1
Olanzapine	78	6.0	6.0
Pemetrexed Disodium	28	6.0	6.0
Insulin Glargine-Yfgn	16	6.0	6.0
Spironolactone	100	6.0	6.0
Haloperidol Lactate	18	5.9	5.9
Carboplatin	90	5.9	5.9
Methoxy Polyethylene Glycol-Epoetin Beta	8	5.9	5.9
Human Insulin	9	5.9	5.9
Erlotinib Hydrochloride	9	5.9	5.9
Atenolol	93	5.8	5.8
Carbamazepine	47	5.8	5.8
Lithium Carbonate	12	5.8	5.8
Ziprasidone Mesylate	10	5.7	5.7
Haloperidol	17	5.7	5.7
Calcitriol Capsules 0.25 Mcg	14	5.7	5.7
Calcitriol Capsules 0.5 Mcg	14	5.7	5.7
Metoclopramide	38	5.7	5.7
Cefepime	10	5.7	5.7
Senna Leaf	16	5.7	5.7
Calcitriol	14	5.6	5.6
Chlorthalidone	8	5.6	5.6
Niacin	8	5.6	5.6
Brentuximab Vedotin	7	5.6	5.6
Deferasirox	18	5.5	5.5
Metformin Hcl	37	5.5	5.5
Guaifenesin	20	5.4	5.4
Exemestane	14	5.3	5.3
Cetirizine Hcl	6	5.3	5.3
Anastrozole Tablets	14	5.3	5.3
Carvedilol	85	5.2	5.2
Carboxymethylcellulose Sodium	6	5.2	5.2
Lisinopril And Hydrochlorothiazide Tablets	5	5.2	5.2
Leucovorin Calcium	12	5.1	5.1
Ziprasidone	11	5.1	5.1
Eplerenone	8	5.1	5.1
Cefepime Hydrochloride	10	5.1	5.1
Triamcinolone Acetonide Ointment Usp, 0.05%	14	4.9	4.9
Rifampicin	6	4.8	4.8
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	4.7	4.8
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	4.7	4.7
Insulin Human	23	4.7	4.7
Dapagliflozin	18	4.7	4.7
Dabrafenib	12	4.6	4.6
Linezolid	16	4.4	4.4
Oseltamivir Phosphate	13	4.3	4.3
Pyrazinamide	5	4.3	4.3
Fluorouracil Cream, 0.5%	39	4.2	4.2
Tafamidis	6	4.1	4.1
Fluorouracil	39	4.1	4.1
Risperidone	66	4.1	4.1
Clozapine	62	4.1	4.1
Trametinib	12	4.0	4.0
Glipizide	30	4.0	4.0
Pitavastatin Calcium	5	4.0	4.0
Pertuzumab	13	3.9	3.9
Dofetilide	5	3.9	3.9
Icosapent Ethyl	4	3.8	3.8
Pembrolizumab	46	3.6	3.6
Sevelamer Carbonate	5	3.5	3.5
Gemcitabine	17	3.5	3.5
Erlotinib	4	3.4	3.4
Sunitinib Malate	16	3.3	3.3
Carbidopa And Levodopa	19	3.3	3.3
Trastuzumab	27	3.2	3.2
Prasugrel Hydrochloride	4	3.2	3.2
Temozolomide	8	3.1	3.1
Gemcitabine Hydrochloride	20	3.1	3.1
Tobramycin	9	3.0	3.0
Eculizumab	20	3.0	3.0
Alpelisib	3	2.8	2.8
Rucaparib	3	2.8	2.8
Cetuximab	10	2.6	2.6
Axitinib	6	2.5	2.5
Pazopanib Hydrochloride	8	2.4	2.4
Romosozumab-Aqqg	4	2.4	2.4
Pseudoephedrine Hcl	3	2.2	2.2
Hydrocodone Bitartrate	11	2.1	2.1
Elexacaftor, Tezacaftor, And Ivacaftor	3	2.0	2.0
Dalfampridine	17	1.9	1.9
Pegfilgrastim	23	1.9	1.9
Somatropin	16	1.8	1.8
Aflibercept	6	1.6	1.6
Abaloparatide	5	1.4	1.4
Nirmatrelvir And Ritonavir	9	1.3	1.3
Droxidopa	3	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.