Reaction

Dermatitis Exfoliative Generalised reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,392 reports · 159 co-occurring drugs

As of the last recalculation, Dermatitis Exfoliative Generalised appears in 3,392 FAERS reports alongside 159 co-occurring drug terms. The strongest observed disproportionality signal is APALUTAMIDE (PRR 31.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Apalutamide	59	31.3	31.5
Brentuximab Vedotin	35	21.2	21.2
Rifampin	37	15.7	15.8
Desloratadine	26	15.0	15.0
Amoxicillin And Clavulanate Potassium	59	13.5	13.6
Terbinafine Hydrochloride	19	13.2	13.2
Meropenem	65	12.7	12.7
Febuxostat Tablets 40 Mg	20	12.1	12.2
Febuxostat Tablets 80 Mg	20	12.1	12.2
Iohexol	16	11.9	11.9
Bendamustine Hcl	29	11.6	11.6
Valacyclovir	76	11.4	11.4
Daptomycin	17	11.4	11.4
Vemurafenib	22	11.3	11.3
Posaconazole Delayed-Release	19	10.7	10.7
Sulfamethoxazole And Trimethoprim	140	10.6	10.6
Amoxicillin	123	10.2	10.2
Darunavir	25	10.2	10.2
Vancomycin	93	10.1	10.1
Ceftriaxone	53	10.1	10.1
Vancomycin Hydrochloride	104	10.0	10.0
Fondaparinux Sodium	13	9.9	9.9
Atazanavir	23	9.9	9.9
Allopurinol	235	9.8	9.8
Rifampicin	16	9.7	9.8
Nemolizumab-Ilto	20	9.7	9.7
Ceftriaxone Sodium	59	9.6	9.6
Pyrazinamide	14	9.2	9.2
Ampicillin	12	8.9	8.9
Ampicillin Sodium	12	8.9	8.9
Piperacillin Sodium,Tazobactam Sodium	38	8.9	8.9
Nevirapine	13	8.9	8.9
Mometasone	26	8.8	8.8
Bendamustine Hydrochloride	17	8.7	8.8
Micafungin Sodium	12	8.7	8.7
Cefuroxime	16	8.6	8.6
Dexamethasone Sodium Phosphate	14	8.5	8.5
Gentamicin	17	8.0	8.0
Loperamide Hydrochloride Oral	13	7.8	7.8
Valacyclovir Hydrochloride	87	7.7	7.8
Cefepime Hydrochloride	20	7.7	7.7
Daspone	12	7.6	7.6
Dapsone Gel, 5%	12	7.6	7.6
Enoxaparin Sodium	69	7.5	7.5
Anakinra	20	7.4	7.4
Febuxostat	20	7.4	7.4
Adalimumab-Adaz	62	7.3	7.3
Hydroxyzine	56	7.3	7.3
Isoniazid	19	7.2	7.2
Posaconazole	19	7.2	7.2
Clobetasol Propionate Ointment Usp, 0.05%	12	7.2	7.2
Clobetasol Propionate	12	7.1	7.1
Esomeprazole	70	7.1	7.1
Dapsone	12	6.9	6.9
Encorafenib	11	6.8	6.8
Levofloxacin	65	6.7	6.7
Levofloxacin In 5% Dextrose	65	6.7	6.7
Hydrocortisone Acetate	78	6.7	6.7
Gentamicin Sulfate	17	6.6	6.6
Anti-Itch	71	6.6	6.6
Anti-Pruritic	71	6.6	6.6
Antipruritic (Anti-Itch)	71	6.6	6.6
Cool Relief Gel With Aloe	71	6.6	6.6
Drs. Hydrocortisone	71	6.6	6.6
Hydrocortisone Continuous Spray	71	6.6	6.6
Hydrocortisone Spray	71	6.6	6.6
Anti-Itch Cream	71	6.6	6.6
Hydrocortisone Lotion	71	6.6	6.6
Hydrocortisone Cream 1%	71	6.6	6.6
Hydrocortisone Cream 1/2%	71	6.6	6.6
Hydrocortisone 1%	71	6.6	6.6
Hydrocortisone Cream	71	6.6	6.6
Guselkumab	38	6.6	6.6
Hydroxyzine Hydrochloride	14	6.6	6.6
Hydroxyzine Hydrochloride Oral	14	6.6	6.6
Daratumumab	42	6.5	6.5
Phenytoin	22	6.5	6.5
Leucovorin Calcium	20	6.5	6.5
Azacitidine For	19	6.4	6.4
Adalimumab-Fkjp	48	6.4	6.4
Adalimumab-Aaty	49	6.4	6.4
Midazolam	26	6.4	6.4
Clobazam	25	6.3	6.3
Loperamide Hcl	13	6.2	6.2
Atovaquone	8	6.1	6.1
Colchicine	26	6.1	6.1
Chlorhexidine Gluconate	9	6.1	6.1
Metronidazole Topical	46	6.0	6.0
Midazolam Hydrochloride	26	6.0	6.0
Trametinib	23	5.9	5.9
Piperacillin And Tazobactam	12	5.8	5.8
Norepinephrine	10	5.8	5.8
Metronidazole	59	5.8	5.8
Obinutuzumab	15	5.6	5.6
Cyclosporine	99	5.6	5.6
Ciprofolxacin	64	5.6	5.6
Ciprofloxacin Tablets	64	5.6	5.6
Pemetrexed Disodium	34	5.5	5.5
Thiamine Hydrochloride	11	5.4	5.4
Tamsulosin Hydrochloride	18	5.4	5.4
Filgrastim	33	5.4	5.4
Linezolid	26	5.4	5.4
Dutasteride	7	5.3	5.3
Rabeprazole	19	5.3	5.3
Dabrafenib	18	5.3	5.3
Ustekinumab	86	5.3	5.3
Imatinib	15	5.2	5.2
Clarithromycin	29	5.2	5.2
Norepinephrine Bitartrate	12	5.1	5.1
Insulin Glargine-Yfgn	18	5.1	5.1
Ritonavir	24	5.1	5.1
Amikacin	14	5.1	5.1
Ixekizumab	30	5.0	5.0
Fosaprepitant Dimeglumine	11	4.9	4.9
Heparin Sodium	11	4.9	4.9
Pemetrexed	17	4.9	4.9
Diltiazem Hydrochloride Extended-Release Tablets	9	4.9	4.9
Regorafenib	9	4.8	4.8
Oxazepam	16	4.6	4.6
Methoxy Polyethylene Glycol-Epoetin Beta	8	4.5	4.5
Azacitidine	21	4.4	4.4
Carbamazepine	47	4.4	4.4
Bisoprolol Fumarate	92	4.2	4.2
Secukinumab	107	4.2	4.2
Brimonidine Tartrate	12	4.1	4.1
Bortezomib	59	4.1	4.1
Piperacillin Sodium And Tazobactam Sodium	13	4.1	4.1
Aprepitant	12	4.0	4.0
Risankizumab-Rzaa	52	3.9	3.9
Thiotepa	6	3.9	3.9
Melphalan	14	3.8	3.8
Carboplatin	75	3.7	3.7
Nivolumab	57	3.7	3.7
Etoposide	41	3.5	3.5
Sevelamer Carbonate	6	3.2	3.2
Cladribine	5	3.2	3.2
Bimekizumab	11	3.2	3.2
Acalabrutinib	6	3.0	3.0
Gemcitabine Hydrochloride	26	3.0	3.0
Pembrolizumab	51	3.0	3.0
Fluorouracil Cream, 0.5%	37	3.0	3.0
Gemcitabine	19	3.0	3.0
Fluorouracil	37	3.0	3.0
Ipilimumab	18	2.6	2.6
Cetuximab	13	2.6	2.6
Dupilumab	190	2.5	2.5
Oxaliplatin	29	2.4	2.4
Atezolizumab	15	2.4	2.4
Suvorexant	5	2.4	2.4
Durvalumab	7	2.1	2.1
Venetoclax	21	2.1	2.1
Bosutinib	3	2.1	2.1
Lenalidomide	122	1.8	1.8
Carfilzomib	8	1.7	1.7
Ixazomib	8	1.7	1.7
Ofatumumab	9	1.7	1.7
Relugolix	6	1.6	1.6
Pirfenidone	10	1.5	1.5
Apremilast	26	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.