Reaction

Which drugs are most reported with Metastasis?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,082 reports · 150 co-occurring drugs

As of the last recalculation, Metastasis appears in 7,082 FAERS reports alongside 150 co-occurring drug terms. The strongest observed disproportionality signal is RIBOCICLIB (PRR 43.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ribociclib	438	43.4	44.0
Fulvestrant	349	32.6	32.9
Gefitinib	82	27.0	27.2
Ado-Trastuzumab Emtansine	65	22.9	23.0
Octreotide Acetate	196	19.3	19.4
Erlotinib	61	18.7	18.8
Anastrozole Tablets	133	18.5	18.7
Letrozole	354	17.7	17.8
Bicalutamide	88	17.2	17.3
Letrozole Tablets	269	17.0	17.1
Exemestane	122	17.0	17.1
Trastuzumab	374	16.9	16.9
Bleomycin Sulfate	58	16.6	16.7
Goserelin	74	16.4	16.4
Pertuzumab	148	16.3	16.4
Anastrozole	192	15.8	15.8
Dabrafenib	111	15.7	15.8
Erlotinib Hydrochloride	66	15.6	15.7
Trametinib	110	13.6	13.6
Lapatinib	69	13.2	13.2
Everolimus	219	13.0	13.1
Olaparib	91	12.9	13.0
Capecitabine	372	12.6	12.6
Bendamustine Hydrochloride	49	12.1	12.1
Bendamustine Hcl	63	12.0	12.1
Osimertinib	129	12.0	12.1
Pazopanib Hydrochloride	105	11.6	11.6
Alpelisib	34	11.5	11.6
Docetaxel Anhydrous	248	11.2	11.2
Docetaxel	248	11.2	11.2
Everolimus Tablets	63	11.1	11.2
Sorafenib	77	11.0	11.0
Imatinib	65	10.9	11.0
Regorafenib	41	10.4	10.5
Vemurafenib	40	9.8	9.9
Temozolomide	67	9.4	9.5
Gemcitabine	124	9.4	9.4
Durvalumab	61	8.9	8.9
Fluorouracil Cream, 0.5%	217	8.6	8.6
Ifosfamide	62	8.5	8.6
Fluorouracil	218	8.5	8.5
Panitumumab	43	8.1	8.1
Bevacizumab	325	8.0	8.1
Etoposide	196	8.0	8.0
Zoledronic Acid	105	7.8	7.8
Gemcitabine Hydrochloride	137	7.7	7.7
Cisplatin	198	7.6	7.7
Atezolizumab	99	7.6	7.6
Doxorubicin	215	7.3	7.3
Niraparib	54	7.2	7.2
Paclitaxel	235	7.2	7.2
Paclitaxel (Aibumin-Bound)	191	7.0	7.0
Carboplatin	291	7.0	7.0
Lanreotide Acetate	18	6.8	6.8
Pemetrexed	48	6.6	6.6
Abiraterone	30	6.5	6.5
Cyclophosphamide Injection, Solution	356	6.2	6.2
Cyclophosphamide	356	6.2	6.2
Cyclophosphamide For Injection	356	6.2	6.2
Leuprolide Acetate	157	6.1	6.1
Oxaliplatin	135	5.4	5.4
Mesna Injection	15	5.3	5.4
Mesna	15	5.2	5.3
Imatinib Mesylate	48	5.1	5.1
Melphalan	39	5.1	5.1
Apalutamide	20	5.0	5.0
Pemetrexed Disodium	64	5.0	5.0
Melphalan Hydrochloride	42	4.9	5.0
Doxorubicin Hydrochloride	53	4.8	4.8
Dalteparin Sodium	17	4.7	4.7
Busulfan	24	4.5	4.5
Leucovorin Calcium	29	4.5	4.5
Abiraterone Acetate	62	4.5	4.5
Granisetron Hydrochloride	15	4.2	4.2
Palbociclib	134	4.2	4.2
Morphine	104	4.1	4.1
Fam-Trastuzumab Deruxtecan-Nxki	14	4.1	4.1
Enzalutamide	78	3.9	3.9
Granisetron	14	3.9	3.9
Cholestyramine	15	3.7	3.7
Thalidomide	45	3.6	3.6
Ipilimumab	52	3.6	3.6
Atropine	10	3.6	3.6
Ganciclovir	12	3.5	3.5
Mercaptopurine	20	3.4	3.4
Ganciclovir Sodium	12	3.3	3.3
Denosumab	224	3.3	3.3
Valsartan And Hydrochlorothiazide	15	3.3	3.3
Irinotecan Hydrochloride	14	3.2	3.2
Cetuximab	34	3.2	3.2
Nivolumab	103	3.2	3.2
Abemaciclib	21	3.1	3.1
Cytarabine	62	3.1	3.1
Sitagliptin And Metformin Hydrochloride	22	3.0	3.0
Atropine Sulfate	11	3.0	3.0
Prochlorperazine	28	3.0	3.0
Dronabinol	8	2.9	2.9
Rituximab	203	2.9	2.9
Sirolimus	13	2.8	2.8
Filgrastim	36	2.8	2.8
Crizotinib	12	2.8	2.8
Amlodipine Besylate And Valsartan	10	2.7	2.7
Cyclobenzaprine Hydrochloride	8	2.6	2.6
Axitinib	17	2.6	2.6
Mycophenolate Mofetil	111	2.4	2.4
Mycophenolate Mofetil Hydrochloride	111	2.4	2.4
Polatuzumab Vedotin	8	2.4	2.4
Tacrolimus	127	2.4	2.4
Fludarabine Phosphate	32	2.4	2.4
Tacrolimus Ointment 0.1%	99	2.4	2.4
Tacrolimus Extended-Release Capsules	99	2.3	2.4
Rucaparib	7	2.3	2.3
Valsartan Oral	41	2.2	2.2
Cabozantinib	36	2.2	2.2
Pegaspargase	9	2.2	2.2
Ondansetron Hydrochloride	87	2.1	2.1
Sunitinib Malate	28	2.1	2.1
Encorafenib	7	2.1	2.1
Sitagliptin	50	2.0	2.0
Rotigotine	10	2.0	2.0
Ondansetron	75	2.0	2.0
Ondansetron Tablets	75	2.0	2.0
Vincristine Sulfate	20	2.0	2.0
Relugolix	16	2.0	2.0
Thiotepa	6	1.8	1.8
Cladribine	6	1.8	1.8
Lutetium Lu 177 Vipivotide Tetraxetan	8	1.8	1.8
Brentuximab Vedotin	6	1.7	1.7
Pembrolizumab	61	1.7	1.7
Lenvatinib	19	1.7	1.7
Acalabrutinib	7	1.7	1.7
Vismodegib	5	1.7	1.7
Prochlorperazine Maleate	5	1.6	1.6
Memantine	7	1.5	1.5
Memantine Hydrochloride	7	1.5	1.5
Insulin Degludec	11	1.4	1.4
Dexamethasone 1.5 Mg	135	1.4	1.4
Dexlansoprazole	19	1.3	1.3
Obinutuzumab	7	1.3	1.3
Clozapine	51	1.2	1.2
Cortisone Acetate	5	1.2	1.2
Fentanyl Citrate	7	1.2	1.2
Carfilzomib	11	1.1	1.1
Loratadine And Pseudoephedrine Sulfate	3	1.1	1.1
Axicabtagene Ciloleucel	3	0.9	0.9
Trifluridine And Tipiracil	3	0.8	0.8
Methoxy Polyethylene Glycol-Epoetin Beta	3	0.8	0.8
Pegfilgrastim	23	0.7	0.7
Pomalidomide	15	0.4	0.4
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	4	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.