Reaction

Spondylitis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,583 reports · 193 co-occurring drugs

As of the last recalculation, Spondylitis appears in 3,583 FAERS reports alongside 193 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 132.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	182	132.3	135.2
Diclofenac Potassium Tablets	182	132.2	135.1
Diclofenac Potassium	183	103.6	105.4
Cortisone Acetate	179	88.6	89.9
Pseudoephedrine Hydrochloride	137	80.5	81.6
Pseudoephedrine Hcl	137	75.1	76.0
Desoximetasone	197	63.5	64.2
Tofacitinib Citrate	131	60.2	60.8
Naproxen Sodium Tablet, Coated	132	58.8	59.3
Naproxen Sodium, Coated Tablets	132	58.8	59.3
Naproxen Sodium 220Mg	132	58.7	59.2
Hydrocortisone Sodium Succinate	64	40.2	40.5
Diclofenac Sodium 1%	213	36.8	37.0
Diclofenac Sodium Topical	213	36.8	37.0
Diclofenac Sodium Topical Gel, 1%	213	36.7	36.9
Cetirizine Hydrochloride Allergy	177	35.7	35.9
Cetirizine Hydrochloride Tablets	177	35.7	35.9
Adalimumab-Fkjp	250	33.6	33.8
Diltiazem Hydrochloride Extended-Release Tablets	64	33.3	33.4
Adalimumab-Aaty	247	32.5	32.7
Adalimumab-Adaz	263	31.2	31.3
Diphenhydramine Hydrochloride Capsule, Liquid Filled	111	31.1	31.3
Doxyclycline Hyclate	87	30.4	30.5
Chlorhexidine Gluconate	43	27.7	27.8
Acetaminophen And Codeine	55	26.6	26.7
Sulfasalazine	267	21.3	21.4
Methylprednisolone Sodium Succinate	160	20.9	21.0
Triamcinolone Acetonide Ointment Usp, 0.05%	82	20.8	20.9
Sarilumab	92	20.7	20.8
Quetiapine Fumarate	102	20.6	20.7
Erythromycin	62	19.5	19.6
Calcium Gluconate	40	19.5	19.6
Diclofenac	251	18.1	18.2
Alendronate Sodium	286	17.8	17.9
Golimumab	244	17.7	17.7
Cetirizine	213	16.9	16.9
Antacid	131	16.6	16.6
Triamcinolone Acetonide	83	16.0	16.0
Hydroxychloroquine	192	15.7	15.8
Tramadol Hydrochloride	94	14.9	14.9
Calcium Carbonate	156	14.1	14.1
Azathioprine	199	13.8	13.9
Hydroxychloroquine Sulfate	205	13.8	13.8
Risedronate Sodium	72	13.7	13.7
Ustekinumab	225	13.6	13.6
Isopropyl Alcohol	77	13.5	13.5
Tocilizumab	248	13.5	13.5
Certolizumab Pegol	238	12.6	12.6
Cetiirizine	89	12.5	12.5
Secukinumab	315	12.3	12.4
Leflunomide	210	12.3	12.3
Diltiazem Hydrochloride	70	12.0	12.0
Alcohol	77	11.8	11.8
Celecoxib	249	11.7	11.8
Mesalamine	110	11.7	11.7
Hydrocortisone Acetate	139	11.5	11.5
Diclofenac Sodium	274	11.4	11.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	58	11.3	11.3
Oxycodone And Acetaminophen Tablets	23	11.3	11.3
Hydrocortisone	164	11.1	11.2
Minocycline	22	11.0	11.0
Ascorbic Acid	39	9.8	9.9
Naproxen	127	9.7	9.7
Doxycycline Hyclate	105	9.3	9.3
Naproxen Sodium	214	9.2	9.2
Doxycycline	105	9.2	9.2
Abatacept	207	9.2	9.2
Adalimumab	866	9.1	9.1
Morphine	111	8.9	8.9
Tofacitinib	256	8.6	8.6
Vedolizumab	123	8.6	8.6
Cetirizine Hydrochloride	226	8.4	8.4
Anti-Itch	92	8.2	8.2
Anti-Pruritic	92	8.2	8.2
Antipruritic (Anti-Itch)	92	8.2	8.2
Cool Relief Gel With Aloe	92	8.2	8.2
Drs. Hydrocortisone	92	8.2	8.2
Hydrocortisone Continuous Spray	92	8.2	8.2
Hydrocortisone Spray	92	8.2	8.2
Anti-Itch Cream	92	8.2	8.2
Hydrocortisone Lotion	92	8.2	8.2
Hydrocortisone Cream 1%	92	8.2	8.2
Hydrocortisone Cream 1/2%	92	8.2	8.2
Hydrocortisone 1%	92	8.1	8.2
Folic Acid	322	8.1	8.2
Apremilast	195	8.1	8.1
Hydrocortisone Cream	92	8.1	8.1
Upadacitinib	110	8.1	8.1
Pantoprazole Sodium In 0.9% Sodium Chloride	84	8.0	8.0
Pantoprazole Sodium Injection	84	8.0	8.0
Meloxicam	77	7.8	7.9
Vitamin C	120	7.8	7.8
Biotin	41	7.7	7.7
Aprepitant	23	7.3	7.3
Methylprednisolone	166	7.3	7.3
Fosaprepitant Dimeglumine	17	7.2	7.2
Botulinum Toxin Type A	15	7.0	7.1
Infliximab	248	7.0	7.0
Icosapent Ethyl	10	6.8	6.8
Methotrexate	429	6.6	6.6
Meclizine Hydrochloride	22	6.6	6.6
Oxycodone And Acetaminophen	26	6.5	6.5
Ibuprofen Capsule	212	6.5	6.5
Ibuprofen Tablet, Film Coated	212	6.5	6.5
Ibupfrofen	212	6.5	6.5
Ibuprofen Tablets Usp, 200Mg	212	6.5	6.5
Ibuprofen Oral	212	6.5	6.5
Ibuprofen Capsules 200 Mg	212	6.5	6.5
Ibuprofen 200 Mg	212	6.5	6.5
Ibuprofen 200Mg	212	6.5	6.5
Meclizine	18	6.4	6.4
Alendronate Sodium Tablet	20	6.3	6.3
Magnesium	87	6.3	6.3
Methotrexate Sodium	465	6.2	6.2
Indomethacin	14	6.2	6.2
Ibuprofen	255	5.8	5.8
Diphenhydramine Hydrochloride	159	5.8	5.8
Acetaminophen Tablet Extended Release	237	5.7	5.7
Pain Reliever	237	5.7	5.7
Acetaminophen 500Mg	237	5.7	5.7
Meclizine Hcl 12.5Mg	13	5.6	5.6
Meclizine Hcl 25Mg	13	5.6	5.6
Meclizine Hcl 12.5 Mg	13	5.6	5.6
Meclizine Hcl 25 Mg	13	5.6	5.6
Rituximab	188	5.4	5.4
Quetiapine	170	5.3	5.3
Cyanocobalamin	30	5.3	5.3
Cholestyramine	11	5.3	5.3
Infliximab-Dyyb	26	5.2	5.2
Calcium	129	5.2	5.2
Pantoprazole	211	5.1	5.1
Risankizumab-Rzaa	70	5.1	5.1
Pregabalin	224	5.0	5.0
Anakinra	14	4.9	4.9
Diroximel Fumarate	10	4.9	4.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	7	4.7	4.7
Acetaminophen	337	4.7	4.7
Mirabegron	31	4.7	4.7
Bimekizumab	17	4.7	4.7
Tizanidine	19	4.6	4.6
Mycophenolate Mofetil Hydrochloride	106	4.6	4.6
Ergocalciferol	281	4.5	4.5
Tizanidine Hydrochloride	14	4.5	4.5
Oxycodone	140	4.5	4.5
Niraparib	17	4.5	4.5
Salicylic Acid	40	4.4	4.4
Ramipril	92	4.4	4.4
Etanercept	399	4.2	4.2
Mycophenolate Mofetil	96	4.2	4.2
Misoprostol	7	4.2	4.2
Ibuprofen And Diphenhydramine Citrate	16	4.0	4.0
Duloxetine	47	4.0	4.0
Ropinirole	10	3.8	3.8
Morphine Sulfate	77	3.7	3.7
Fish Oil	56	3.6	3.6
Estradiol Gel 0.1%	27	3.5	3.5
Estradiol Transdermal	27	3.5	3.5
Sodium Oxybate	39	3.5	3.5
Oxycodone Hydrochloride And Acetaminophen	58	3.4	3.5
Ravulizumab	8	3.4	3.4
Ibuprofen Tablets, Coated	25	3.4	3.4
Atomoxetine Hydrochloride	14	3.4	3.4
Ibuprofen Sodium	25	3.4	3.4
Levocetirizine Dihydrochloride	14	3.4	3.4
Azelastine	10	3.2	3.2
Ocrelizumab	33	3.1	3.1
Acetaminophen, Aspirin (Nsaid) And Caffeine	9	3.1	3.1
Interferon Beta-1A	100	3.1	3.1
Natalizumab	93	3.0	3.0
Memantine	7	3.0	3.0
Memantine Hydrochloride	7	3.0	3.0
Asfotase Alfa	5	2.9	2.9
Inclisiran	4	2.9	2.9
Mepolizumab	23	2.7	2.7
Erenumab-Aooe	25	2.6	2.6
Siponimod	4	2.6	2.6
Acetaminophen, Aspirin, And Caffeine	9	2.5	2.5
Tafamidis	5	2.5	2.5
Dimethyl Fumarate	48	2.3	2.3
Guselkumab	13	2.1	2.1
Selinexor	3	2.0	2.0
Isotretinoin	17	2.0	2.0
Rucaparib	3	2.0	2.0
Teriparatide	37	1.9	1.9
Teriflunomide	14	1.8	1.8
Peginterferon Beta-1A	4	1.8	1.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	3	1.7	1.7
Ixekizumab	11	1.7	1.7
Durvalumab	6	1.7	1.7
Dalfampridine	20	1.6	1.6
Buprenorphine	23	1.4	1.4
Evolocumab	24	0.9	0.9
Cinacalcet Hydrochloride	6	0.7	0.7

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.