Reaction

Mouth Swelling reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,674 reports · 218 co-occurring drugs

As of the last recalculation, Mouth Swelling appears in 5,674 FAERS reports alongside 218 co-occurring drug terms. The strongest observed disproportionality signal is TRIMETHOPRIM (PRR 12.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Trimethoprim	39	12.2	12.3
Fexofenadine	49	11.0	11.0
Desloratadine	27	9.3	9.3
Omalizumab	191	8.5	8.5
Dimenhydrinate	23	7.9	8.0
Erythromycin	37	7.3	7.3
Amitriptyline Hydrochloride	34	7.1	7.2
Anastrozole Tablets	40	6.9	6.9
Eptinezumab-Jjmr	17	6.9	6.9
Quinine	16	6.9	6.9
Iohexol	15	6.7	6.7
Clarithromycin	60	6.5	6.5
Alpelisib	15	6.3	6.3
Cetiirizine	71	6.2	6.2
Tranexamic Acid	15	6.2	6.2
Exemestane	34	5.9	5.9
Cetirizine	118	5.7	5.7
Docosanol	22	5.5	5.5
Glycerin, Lidocaine	21	5.5	5.5
Cetirizine Hydrochloride Allergy	45	5.5	5.5
Cetirizine Hydrochloride Tablets	45	5.5	5.5
Terbinafine Hydrochloride	13	5.4	5.4
Umeclidinium Bromide And Vilanterol Trifenatate	24	5.3	5.3
Sumatriptan Succinate	33	4.8	4.8
Fulvestrant	43	4.8	4.8
Doxycycline	86	4.7	4.7
Doxycycline Hyclate	85	4.7	4.7
Anastrozole	46	4.6	4.6
Amoxicillin	94	4.6	4.6
Epinephrine	76	4.3	4.3
Levocetirizine Dihydrochloride	28	4.3	4.3
Umeclidinium	10	4.1	4.1
Loratadine Oral	52	3.9	3.9
Budesonide, Glycopyrrolate, And Formoterol Fumarate	11	3.9	3.9
Diphenhydramine Hydrochloride	169	3.8	3.8
Nitrofurantoin	17	3.8	3.8
Letrozole Tablets	49	3.8	3.8
Nitrofurantoin (Monohydrate/Macrocrystals)	17	3.7	3.7
Everolimus	50	3.6	3.6
Chlorhexidine Gluconate	9	3.6	3.6
Adrenalinum	40	3.6	3.6
Cetirizine Hydrochloride	154	3.5	3.5
Ramipril	115	3.5	3.5
Naproxen	73	3.4	3.4
Montelukast	77	3.4	3.4
Sorafenib	19	3.4	3.4
Avapritinib	11	3.3	3.3
Anti-Itch	60	3.3	3.3
Anti-Pruritic	60	3.3	3.3
Antipruritic (Anti-Itch)	60	3.3	3.3
Cool Relief Gel With Aloe	60	3.3	3.3
Drs. Hydrocortisone	60	3.3	3.3
Hydrocortisone Continuous Spray	60	3.3	3.3
Hydrocortisone Spray	60	3.3	3.3
Anti-Itch Cream	60	3.3	3.3
Hydrocortisone Lotion	60	3.3	3.3
Hydrocortisone Cream 1%	60	3.3	3.3
Hydrocortisone Cream 1/2%	60	3.3	3.3
Hydrocortisone 1%	60	3.3	3.3
Cabozantinib	43	3.3	3.3
Letrozole	55	3.3	3.3
Hydrocortisone Cream	60	3.3	3.3
Infliximab-Dyyb	26	3.3	3.3
Mupirocin	12	3.3	3.3
Metronidazole Topical	42	3.3	3.3
Mupirocin Calcium	12	3.2	3.2
Sumatriptan	33	3.2	3.2
Rimegepant Sulfate	11	3.2	3.2
Clopidogrel Bisulfate	87	3.2	3.2
Senna	18	3.1	3.1
Nirmatrelvir And Ritonavir	46	3.1	3.1
Clindamycin	24	3.1	3.1
Docusate Sodium 100Mg	20	3.1	3.1
Senna Leaf	19	3.0	3.0
Sennosides 8.6 Mg Tablets	17	3.0	3.0
Lactulose	31	3.0	3.0
Miconazole Nitrate	7	2.9	2.9
Zoledronic Acid	32	2.9	2.9
Diphenhydramine	50	2.9	2.9
Doxepin	8	2.9	2.9
Buprenorphine Hydrochloride, Naloxone Hydrochloride	19	2.9	2.9
Fremanezumab-Vfrm	9	2.9	2.9
Mirabegron	30	2.9	2.9
Naproxen Sodium	108	2.8	2.8
Hydroxyzine Hydrochloride	10	2.8	2.8
Hydroxyzine Hydrochloride Oral	10	2.8	2.8
Omeprazole	253	2.8	2.8
Losartan	130	2.8	2.8
Loratadine	80	2.8	2.8
Ketoconazole Foam	11	2.7	2.7
Ketoconazole Cream, 2%	11	2.7	2.7
Sennosides	22	2.7	2.7
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	22	2.7	2.7
Fluticasone Furoate And Vilanterol Trifenatate	26	2.7	2.7
Colchicine	19	2.7	2.7
Denosumab	144	2.6	2.7
Ibuprofen Tablets, Coated	30	2.6	2.6
Duloxetine	49	2.6	2.6
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	2.6	2.6
Ibuprofen Sodium	30	2.6	2.6
Pitavastatin Calcium	7	2.5	2.5
Nicotine Polacrilex	26	2.5	2.5
Rucaparib	6	2.5	2.5
Prednisolone Acetate	7	2.5	2.5
Valbenazine	17	2.5	2.5
Thyroid, Porcine	7	2.4	2.4
Omeprazole Magnesium	284	2.4	2.4
Ropinirole	10	2.4	2.4
Benralizumab	13	2.4	2.4
Doxyclycline Hyclate	11	2.4	2.4
Fesoterodine Fumarate	7	2.4	2.4
Ribociclib	20	2.3	2.3
Famotidine	74	2.3	2.3
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	13	2.3	2.3
Naproxen Sodium, Pseudoephedrine Hydrochloride	13	2.3	2.3
Iron Sucrose	6	2.3	2.3
Lovastatin	16	2.3	2.3
Inclisiran	5	2.3	2.3
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	31	2.3	2.3
Glatiramer Acetate	37	2.3	2.3
Estradiol Gel 0.1%	28	2.3	2.3
Estradiol Transdermal	28	2.3	2.3
Oxybutynin	18	2.3	2.3
Tofacitinib Citrate	8	2.2	2.2
Lisdexamfetamine Dimesylate	20	2.2	2.2
Naproxen Sodium Tablet	32	2.2	2.2
Piperacillin Sodium,Tazobactam Sodium	16	2.2	2.2
Anakinra	10	2.2	2.2
Pregabalin	159	2.2	2.2
Lacosamide	22	2.2	2.2
Liraglutide	29	2.2	2.2
Diroximel Fumarate	7	2.2	2.2
Oxcarbazepine	19	2.1	2.1
Acetaminophen And Codeine	7	2.1	2.1
Lurasidone Hydrochloride	12	2.1	2.1
Ticagrelor	18	2.1	2.1
Multivitamin	28	2.1	2.1
Alirocumab	14	2.1	2.1
Fexofenadine Hydrochloride	12	2.0	2.0
Brexpiprazole	9	2.0	2.0
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	19	2.0	2.0
Sunitinib Malate	21	2.0	2.0
Carboxymethylcellulose Sodium	5	2.0	2.0
Trastuzumab	36	1.9	1.9
Loratadine Tablet	28	1.9	1.9
Baricitinib	5	1.9	1.9
Mometasone Furoate And Formoterol Fumarate Dihydrate	8	1.9	1.9
Memantine	7	1.9	1.9
Memantine Hydrochloride	7	1.9	1.9
Panitumumab	8	1.9	1.9
Apalutamide	6	1.9	1.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	21	1.9	1.9
Loratadine And Pseudoephedrine Sulfate	4	1.8	1.8
Acalabrutinib	6	1.8	1.8
Nicotine	20	1.8	1.8
Brentuximab Vedotin	5	1.8	1.8
Naltrexone	15	1.8	1.8
Pegvaliase-Pqpz	4	1.8	1.8
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	20	1.8	1.8
Dapagliflozin	15	1.8	1.8
Nilotinib	14	1.7	1.7
Belimumab	15	1.7	1.7
Bimekizumab	10	1.7	1.7
Imatinib Mesylate	13	1.7	1.7
Voclosporin	4	1.7	1.7
Lenvatinib	15	1.7	1.7
Clobazam	11	1.7	1.7
Niraparib	10	1.7	1.7
Palbociclib	42	1.6	1.6
Regorafenib	5	1.6	1.6
Onabotulinumtoxina	33	1.6	1.6
Armodafinil	9	1.6	1.6
Ledipasvir And Sofosbuvir	8	1.5	1.5
Trametinib	10	1.5	1.5
Ranitidine	80	1.5	1.5
Carbidopa And Levodopa	19	1.5	1.5
Asfotase Alfa	4	1.5	1.5
Sacubitril And Valsartan	46	1.5	1.5
Dabrafenib	8	1.4	1.4
Vibegron	3	1.4	1.4
Abaloparatide	11	1.4	1.4
Cabotegravir	3	1.4	1.4
Romosozumab-Aqqg	5	1.4	1.4
Buprenorphine	34	1.3	1.4
Glecaprevir And Pibrentasvir	4	1.3	1.3
Pimavanserin Tartrate	20	1.3	1.3
Teriflunomide	16	1.3	1.3
Orlistat	9	1.3	1.3
Selinexor	3	1.3	1.3
Medroxyprogesterone Acetate	17	1.3	1.3
Vismodegib	3	1.2	1.2
Bosutinib	3	1.2	1.2
Alteplase	5	1.2	1.2
Cenegermin-Bkbj	4	1.2	1.2
Botulinum Toxin Type A	4	1.2	1.2
Ixazomib	9	1.1	1.1
Bimatoprost	9	1.1	1.1
Axitinib	6	1.1	1.1
Lifitegrast	5	1.1	1.1
Sarilumab	8	1.1	1.1
Canagliflozin	9	1.1	1.1
Abemaciclib	6	1.1	1.1
Nemolizumab-Ilto	3	0.9	0.9
Dimethyl Fumarate	29	0.9	0.9
Velpatasvir And Sofosbuvir	3	0.9	0.9
Patiromer	3	0.8	0.8
Dupilumab	101	0.8	0.8
Dulaglutide	18	0.7	0.7
Galcanezumab-Gnlm	6	0.7	0.7
Ixekizumab	7	0.7	0.7
Pomalidomide	19	0.7	0.7
Ranitidine Hydrochloride	10	0.7	0.7
Guselkumab	6	0.6	0.6
Erenumab-Aooe	9	0.6	0.6
Evolocumab	26	0.6	0.6
Salicylic Acid	8	0.6	0.6
Tirzepatide	19	0.4	0.4
Adapalene	19	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.