Reaction

Clostridial Infection reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,370 reports · 147 co-occurring drugs

As of the last recalculation, Clostridial Infection appears in 3,370 FAERS reports alongside 147 co-occurring drug terms. The strongest observed disproportionality signal is PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM (PRR 18.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Piperacillin Sodium And Tazobactam Sodium	59	18.9	18.9
Metronidazole	180	18.3	18.4
Piperacillin And Tazobactam	34	16.6	16.6
Cefepime	35	15.2	15.3
Clindamycin	67	14.9	14.9
Metronidazole Topical	109	14.6	14.6
Clindamycin Phosphate	73	13.8	13.8
Cefepime Hydrochloride	35	13.5	13.6
Vancomycin	118	13.0	13.1
Ampicillin	17	12.7	12.8
Ampicillin Sodium	17	12.7	12.8
Vancomycin Hydrochloride	124	12.0	12.0
Cefuroxime	22	12.0	12.0
Gentamicin Sulfate	29	11.4	11.4
Gentamicin	22	10.5	10.5
Leucovorin Calcium	32	10.4	10.4
Piperacillin Sodium,Tazobactam Sodium	41	9.7	9.7
Meropenem	49	9.6	9.6
Anti-Thymocyte Globulin (Rabbit)	12	9.2	9.2
Mesna	12	8.8	8.8
Misoprostol	13	8.3	8.3
Mesna Injection	11	8.2	8.3
Melphalan Hydrochloride	33	8.2	8.2
Cytarabine	78	8.2	8.2
Cefazolin	12	8.1	8.2
Ceftriaxone Sodium	49	8.0	8.0
Ceftriaxone	41	7.8	7.8
Dalteparin Sodium	13	7.6	7.6
Norepinephrine	13	7.5	7.5
Norepinephrine Bitartrate	17	7.3	7.3
Etoposide	84	7.2	7.2
Cefazolin Sodium	14	7.2	7.2
Mercaptopurine	20	7.2	7.2
Mesalamine	64	7.2	7.2
Cetuximab	35	7.0	7.0
Ifosfamide	24	6.9	6.9
Amikacin	19	6.9	6.9
Basiliximab	13	6.8	6.9
Melphalan	25	6.8	6.8
Magnesium Sulfate In Water For	14	6.8	6.8
Magnesium Sulfate Heptahydrate	14	6.7	6.7
Magnesium Sulfate	14	6.6	6.7
Ciprofloxacin Hydrochloride And Hydrocortisone	22	6.6	6.6
Fluconazole	73	6.6	6.6
Vincristine Sulfate	30	6.4	6.4
Diphenoxylate Hydrochloride And Atropine Sulfate	14	6.3	6.3
Trimethoprim	12	6.3	6.3
Tolterodine Tartrate	9	6.2	6.2
Bendamustine Hydrochloride	12	6.2	6.2
Levofloxacin	59	6.1	6.1
Levofloxacin In 5% Dextrose	59	6.1	6.1
Cephalexin	21	6.0	6.0
Amoxicillin And Clavulanate Potassium	26	5.9	6.0
Tacrolimus Ointment 0.1%	115	5.9	5.9
Fludarabine Phosphate	37	5.9	5.9
Tacrolimus Extended-Release Capsules	115	5.9	5.9
Ganciclovir Sodium	10	5.9	5.9
Ciprofloxacin	85	5.8	5.8
Azacitidine For	17	5.8	5.8
Ciprofloxacin Hydrochloride	89	5.8	5.8
Tacrolimus	141	5.8	5.8
Epoetin Alfa	11	5.8	5.8
Linezolid	27	5.6	5.6
Ciprofolxacin	63	5.5	5.5
Ciprofloxacin Tablets	63	5.5	5.5
Nystatin Ointment	23	5.4	5.5
Ganciclovir	9	5.4	5.4
Nystatin Cream	23	5.4	5.4
Itraconazole	10	5.3	5.3
Hydrocortisone Sodium Succinate	8	5.3	5.3
Calcium Gluconate	10	5.1	5.1
Cholestyramine	10	5.1	5.1
Interferon Beta-1A	153	5.1	5.1
Sodium Bicarbonate	19	5.1	5.1
Sodium Bicarbonate Injection,	19	5.1	5.1
Aflibercept	25	5.0	5.0
Warfarin Sodium	36	4.8	4.8
Drs. Clotrimazole	9	4.8	4.8
Family Wellness Clotrimazole	9	4.8	4.8
Clotrimazole Topical	9	4.8	4.8
Bendamustine Hcl	12	4.8	4.8
Cyclophosphamide Injection, Solution	133	4.8	4.8
Cyclophosphamide	133	4.8	4.8
Cyclophosphamide For Injection	133	4.8	4.8
Isosorbide Mononitrate	16	4.8	4.8
Cisplatin	59	4.7	4.7
Deferasirox	20	4.7	4.7
Dapsone	8	4.6	4.6
Azacitidine	22	4.6	4.6
Sirolimus	10	4.6	4.6
Fluorouracil Cream, 0.5%	56	4.6	4.6
Doxorubicin Hydrochloride	24	4.6	4.6
Clotrimazole	9	4.5	4.5
Fluorouracil	56	4.5	4.5
Tizanidine Hydrochloride	13	4.5	4.5
Erlotinib Hydrochloride	9	4.5	4.5
Daspone	7	4.4	4.4
Dapsone Gel, 5%	7	4.4	4.4
Sennosides 8.6 Mg Tablets	15	4.4	4.4
Senna	15	4.4	4.4
Enoxaparin Sodium	40	4.3	4.3
Raloxifene Hydrochloride	10	4.2	4.2
Capecitabine	61	4.2	4.2
Extended Phenytoin Sodium	11	4.1	4.1
Infliximab	139	4.1	4.1
Amlodipine Besylate And Benazepril Hydrochloride	6	4.0	4.0
Busulfan	10	3.9	3.9
Bortezomib	56	3.9	3.9
Docetaxel Anhydrous	40	3.7	3.7
Docetaxel	40	3.7	3.7
Micafungin Sodium	5	3.6	3.6
Brentuximab Vedotin	6	3.6	3.6
Oxaliplatin	43	3.6	3.6
Lapatinib	9	3.6	3.6
Temozolomide	12	3.5	3.5
Trastuzumab	37	3.4	3.4
Carboplatin	68	3.4	3.4
Daptomycin	5	3.4	3.4
Thiotepa	5	3.2	3.2
Gemcitabine	20	3.1	3.1
Doxorubicin	45	3.1	3.1
Isotretinoin	25	3.1	3.1
Bosentan	25	3.1	3.1
Pegaspargase	6	3.0	3.0
Obinutuzumab	8	3.0	3.0
Natalizumab	87	3.0	3.0
Teriparatide	54	3.0	3.0
Pertuzumab	13	3.0	3.0
Vedolizumab	40	2.9	2.9
Irinotecan Hydrochloride	6	2.9	2.9
Thalidomide	17	2.9	2.9
Certolizumab Pegol	51	2.7	2.7
Fosaprepitant Dimeglumine	6	2.7	2.7
Gemcitabine Hydrochloride	23	2.7	2.7
Sorafenib	9	2.7	2.7
Imatinib Mesylate	12	2.7	2.7
Polatuzumab Vedotin	4	2.5	2.5
Romiplostim	6	2.5	2.5
Sofosbuvir	7	2.2	2.2
Paricalcitol	5	2.2	2.2
Ustekinumab	36	2.2	2.2
Pegfilgrastim	34	2.1	2.1
Venetoclax	21	2.1	2.1
Gefitinib	3	2.1	2.1
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	9	1.8	1.8
Hydrocodone Bitartrate	9	1.3	1.3
Lenalidomide	81	1.2	1.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.