Reaction

Left Ventricular Failure reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,369 reports · 159 co-occurring drugs

As of the last recalculation, Left Ventricular Failure appears in 3,369 FAERS reports alongside 159 co-occurring drug terms. The strongest observed disproportionality signal is SELEXIPAG (PRR 22.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Selexipag	90	22.1	22.2
Theophylline	36	19.5	19.6
Theophylline Anhydrous	37	18.6	18.7
Metolazone	32	17.7	17.8
Isosorbide Mononitrate	53	16.0	16.1
Bumetanide	65	15.5	15.5
Torsemide	77	14.7	14.7
Macitentan	154	14.4	14.4
Digoxin	136	12.2	12.2
Eplerenone	24	11.7	11.7
Spironolactone	226	10.6	10.6
Itraconazole	19	10.1	10.1
Captopril	15	9.7	9.7
Bosentan	76	9.5	9.5
Botulinum Toxin Type A	18	9.0	9.0
Bisoprolol Fumarate	188	9.0	9.0
Carfilzomib	40	8.8	8.8
Furosemide	493	8.7	8.7
Tafamidis	16	8.4	8.4
0Xygen	66	8.4	8.4
Oxygen	66	8.4	8.4
Riociguat	43	8.2	8.2
Nitroglycerin	70	8.2	8.2
Tolvaptan	19	8.1	8.1
Febuxostat Tablets 40 Mg	13	7.9	7.9
Febuxostat Tablets 80 Mg	13	7.9	7.9
Tadalafil	124	7.9	7.9
Sotalol Hydrochloride	21	7.8	7.9
Amiodarone Hydrochloride	14	7.7	7.8
Epoprostenol	16	7.6	7.6
Potassium Chloride, Dextrose Monohydrate	109	7.5	7.5
Potassium Chloride Oral	109	7.5	7.5
Potassium Chloride Extended-Release	109	7.5	7.5
Sildenafil Powder,	41	7.2	7.2
Ipratropium Bromide	41	7.2	7.2
Doxorubicin Hydrochloride	37	7.1	7.1
Nebivolol	18	7.0	7.0
Potassium Chloride	123	6.9	6.9
Sildenafil	63	6.8	6.8
Loperamide Hcl	14	6.7	6.8
Mesna Injection	9	6.7	6.8
Mesna	9	6.6	6.6
Ranibizumab	28	6.6	6.6
Doxorubicin	92	6.5	6.5
Enalapril	57	6.4	6.4
Imatinib	18	6.3	6.3
Clopidogrel Bisulfate	102	6.3	6.3
Carvedilol	132	6.2	6.2
Ramipril	121	6.2	6.2
Diltiazem Hydrochloride Extended-Release Tablets	11	6.0	6.0
Felodipine Extended-Release Tablets	11	6.0	6.0
Felodipine	11	6.0	6.0
Esomeprazole Magnesium Capsule, Delayed Release	14	6.0	6.0
Esomeprazole Magnesium Delayed Release Capsules	14	6.0	6.0
Esomeprazole Magnesium Dihydrate	14	6.0	6.0
Febuxostat	16	5.9	5.9
Warfarin	116	5.8	5.8
Ifosfamide	20	5.8	5.8
Enalapril Maleate	23	5.8	5.8
Candesartan Cilexetil	24	5.7	5.7
Sildenafil Citrate	113	5.6	5.6
Aspirin 81 Mg	416	5.6	5.6
Aspirin 325 Mg	415	5.6	5.6
Aspirin	432	5.5	5.6
Sacubitril And Valsartan	101	5.5	5.5
Ambrisentan	108	5.5	5.5
Isosorbide Dinitrate	17	5.4	5.4
Candesartan	30	5.2	5.2
Norepinephrine	9	5.2	5.2
Norepinephrine Bitartrate	12	5.2	5.2
Oxaliplatin	61	5.2	5.2
Metoroprolol Tartrate	54	5.1	5.1
Polatuzumab Vedotin	8	5.1	5.1
Nilotinib	24	5.1	5.1
Exemestane	17	4.9	4.9
Cyclophosphamide Injection, Solution	135	4.9	4.9
Cyclophosphamide	135	4.9	4.9
Cyclophosphamide For Injection	135	4.9	4.9
Loperamide Hydrochloride Oral	8	4.8	4.9
Warfarin Sodium	36	4.8	4.8
Everolimus Tablets	13	4.8	4.8
Sodium Bicarbonate	18	4.8	4.8
Sodium Bicarbonate Injection,	18	4.8	4.8
Testosterone	18	4.8	4.8
Ranolazine	8	4.7	4.7
Trastuzumab	52	4.7	4.7
Ketoprofen	10	4.7	4.7
Sofosbuvir	15	4.7	4.7
Amlodipine Besylate And Benazepril Hydrochloride	7	4.7	4.7
Simvastatin	179	4.6	4.6
Clopidogrel	140	4.5	4.5
Letrozole	44	4.5	4.5
Pravastatin Sodium	14	4.4	4.4
Nifedipine	33	4.4	4.4
Prasugrel Hydrochloride	7	4.3	4.3
Nebivolol Hydrochloride	23	4.2	4.2
Rocuronium Bromide	8	4.2	4.2
Metoprolol Tartrate	178	4.2	4.2
Rabeprazole Sodium	18	4.1	4.1
Metoprolol	161	4.1	4.1
Letrozole Tablets	31	4.0	4.0
Methadone Hydrochloride	7	4.0	4.0
Metoprolol Succinate Er Tablets	40	4.0	4.0
Lapatinib	10	4.0	4.0
Doxazosin Mesylate	23	4.0	4.0
Gemcitabine	25	3.9	3.9
Quinapril Hydrochloride	5	3.9	3.9
Metoprolol Succinate	54	3.9	3.9
Tiotropium Bromide Inhalation Spray	7	3.9	3.9
Cladribine	6	3.9	3.9
Allopurinol	95	3.8	3.8
Capecitabine	56	3.8	3.8
Metformin Hcl	34	3.8	3.8
Hydroxyurea	13	3.8	3.8
Gemcitabine Hydrochloride	32	3.8	3.8
Sevoflurane	5	3.7	3.7
Dronedarone	6	3.6	3.6
Cytarabine	35	3.6	3.6
Bleomycin Sulfate	6	3.6	3.6
Tenofovir Disoproxil Fumarate	19	3.6	3.6
Dapagliflozin	18	3.5	3.6
Apixaban	38	3.5	3.5
Empagliflozin	38	3.5	3.5
Linagliptin	10	3.4	3.4
Prochlorperazine Maleate	5	3.4	3.4
Amlodipine Besylate And Valsartan	6	3.4	3.4
Daptomycin	5	3.4	3.4
Agalsidase Beta	5	3.3	3.3
Glimepiride	21	3.3	3.3
Treprostinil	66	3.3	3.3
Dasatinib	19	3.2	3.2
Busulfan	8	3.1	3.1
Azacitidine	15	3.1	3.1
Fluorouracil Cream, 0.5%	38	3.1	3.1
Fluorouracil	38	3.1	3.1
Everolimus	25	3.1	3.1
Nintedanib	15	3.0	3.0
Vincristine Sulfate	14	3.0	3.0
Rivaroxaban	95	2.9	2.9
Daratumumab	18	2.8	2.8
Bendamustine Hcl	7	2.8	2.8
Bosutinib	4	2.8	2.8
Pertuzumab	12	2.7	2.7
Bortezomib	39	2.7	2.7
Osimertinib	14	2.7	2.7
Clozapine	53	2.6	2.6
Alteplase	6	2.5	2.5
Paclitaxel (Aibumin-Bound)	32	2.4	2.4
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	2.1	2.1
Vemurafenib	4	2.1	2.1
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	3	1.8	1.8
Lenvatinib	9	1.7	1.7
Methoxy Polyethylene Glycol-Epoetin Beta	3	1.7	1.7
Fremanezumab-Vfrm	3	1.6	1.6
Palbociclib	24	1.6	1.6
Diroximel Fumarate	3	1.6	1.6
Abiraterone Acetate	10	1.5	1.5
Aflibercept	7	1.4	1.4
Palivizumab	3	1.2	1.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.