OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Which drugs are most reported with Optic neuritis?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 9,001 reports · 194 co-occurring drugs

As of the last recalculation, Optic Neuritis appears in 9,001 FAERS reports alongside 194 co-occurring drug terms. The strongest observed disproportionality signal is INTERFERON BETA-1A (PRR 24.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Interferon Beta-1A1,67924.524.7
Fingolimod Hcl74721.721.9
Pyrazinamide6516.116.2
Ofatumumab20714.714.8
Linezolid18414.614.7
Teriflunomide25813.613.6
Siponimod5113.313.4
Interferon Beta-1B10813.213.2
Glatiramer Acetate29111.611.7
Rifampicin4911.311.3
Isoniazid7711.111.1
Rifampin6911.011.1
Natalizumab79311.011.0
Alemtuzumab8510.310.3
Ocrelizumab26710.210.3
Moxifloxacin609.99.9
Cladribine399.49.5
Dimethyl Fumarate4719.39.3
Peginterferon Beta-1A488.58.5
Dimenhydrinate398.58.5
Moxifloxacin Hydrochloride667.67.6
Methylprednisolone Sodium Succinate1296.56.5
Diroximel Fumarate336.46.4
Ozanimod Hydrochloride236.46.4
Modafinil815.85.9
Baclofen1794.94.9
Dalfampridine1444.74.7
Adalimumab-Fkjp894.54.5
Methylprednisolone Acetate154.34.3
Adalimumab-Aaty834.14.1
Adalimumab-Adaz914.04.0
Tizanidine403.93.9
Methylprednisolone2263.93.9
Amikacin283.83.8
Amantadine243.63.6
Losartan Potassium And Hydrochlorothiazide183.63.6
Imatinib273.53.6
Dorzolamide Hydrochloride And Timolol Maleate123.53.5
Ipilimumab653.53.5
Tolterodine Tartrate133.43.4
Azathioprine1263.33.3
Tizanidine Hydrochloride253.23.2
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate442.92.9
Rizatriptan Benzoate122.72.7
Sumatriptan Succinate292.72.7
Butalbital, Acetaminophen, And Caffeine122.62.6
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate462.62.6
Primidone112.52.5
Cyanocobalamin352.52.5
Rabeprazole232.42.4
Ravulizumab142.42.4
Triamcinolone Acetonide Ointment Usp, 0.05%242.42.4
Pembrolizumab1072.42.4
Meclizine Hydrochloride202.42.4
Infliximab2202.42.4
Clarithromycin352.42.4
Azithromycin412.42.4
Basiliximab122.42.4
Topiramate932.32.3
Ibuprofen And Diphenhydramine Citrate232.32.3
Azithromycin Monohydrate412.32.3
Nivolumab942.32.3
Levofloxacin582.22.2
Levofloxacin In 5% Dextrose582.22.2
Amphotericin B122.22.2
Meclizine Hcl 12.5Mg132.22.2
Meclizine Hcl 25Mg132.22.2
Meclizine Hcl 12.5 Mg132.22.2
Meclizine Hcl 25 Mg132.22.2
Lubiprostone92.22.2
Zoledronic Acid382.22.2
Diphenhydramine Hydrochloride1542.22.2
Meclizine152.12.1
Oral Semaglutide652.12.1
Lopinavir And Ritonavir122.02.0
Rituximab1822.02.0
Sumatriptan332.02.0
Blinatumomab92.02.0
Armodafinil182.02.0
Carbamazepine572.02.0
Brimonidine Tartrate151.91.9
Diphenhydramine531.91.9
Mycophenolate Mofetil1131.91.9
Mycophenolate Mofetil Hydrochloride1131.91.9
Ergocalciferol3121.91.9
Naproxen Sodium Tablet, Coated111.91.9
Naproxen Sodium, Coated Tablets111.91.9
Naproxen Sodium 220Mg111.91.9
Triamcinolone Acetonide251.91.9
Prednisolone1451.91.9
Prednisolone Oral1451.91.9
Prednisolone Oral Solution1451.91.9
Azithromycin Dihydrate461.81.8
Itraconazole91.81.8
Gabapentin2741.81.8
Vilazodone Hydrochloride71.81.8
Anastrozole Tablets161.71.7
Cholestyramine91.71.7
Ibuprofen Capsule1471.71.7
Ibuprofen Tablet, Film Coated1471.71.7
Ibupfrofen1471.71.7
Ibuprofen Tablets Usp, 200Mg1471.71.7
Ibuprofen Oral1471.71.7
Ibuprofen Capsules 200 Mg1471.71.7
Ibuprofen 200 Mg1471.71.7
Ibuprofen 200Mg1471.71.7
Ibuprofen1991.71.7
Duloxetine Hydrochloride1371.71.7
Nitrofurantoin121.71.7
Raltegravir121.71.7
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide221.71.7
Baricitinib71.71.7
Atezolizumab281.71.7
Abacavir Sulfate71.71.7
Ropinirole111.71.7
Amiodarone Hydrochloride81.71.7
Ado-Trastuzumab Emtansine61.61.6
Timolol Maleate71.61.6
Felodipine Extended-Release Tablets81.61.6
Felodipine81.61.6
Ganciclovir71.61.6
Ganciclovir Sodium71.51.5
Mirabegron251.51.5
Methotrexate Sodium3101.51.5
Tocilizumab731.51.5
Valacyclovir Hydrochloride451.51.5
Ibuprofen Sodium271.51.5
Melphalan141.41.4
Ibuprofen Tablets, Coated261.41.4
Zonisamide91.41.4
Encorafenib61.41.4
Tacrolimus Ointment 0.1%751.41.4
Tacrolimus Extended-Release Capsules751.41.4
Melphalan Hydrochloride151.41.4
Durvalumab121.41.4
Pitavastatin Calcium61.41.4
Fludarabine Phosphate231.41.4
Tenofovir Disoproxil Fumarate Tablets51.31.3
Adalimumab4041.31.3
Brinzolamide51.31.3
Acetaminophen And Codeine71.31.3
Imatinib Mesylate161.31.3
Miconazole Nitrate51.31.3
Norepinephrine61.31.3
Ifosfamide121.31.3
Umeclidinium51.31.3
Etanercept3281.31.3
Oxybutynin161.31.3
Omalizumab461.21.2
Dabrafenib111.21.2
Desvenlafaxine Succinate141.21.2
Lisdexamfetamine Dimesylate171.21.2
Polatuzumab Vedotin51.21.2
Certolizumab Pegol581.11.1
Oxaliplatin361.11.1
Gemcitabine191.11.1
Abatacept651.11.1
Fesoterodine Fumarate51.11.1
Drospirenone And Ethinyl Estradiol201.01.0
Bendamustine Hcl71.01.0
Pemetrexed Disodium171.01.0
Gemcitabine Hydrochloride231.01.0
Agalsidase Beta41.01.0
Fluorouracil331.01.0
Pemetrexed91.01.0
Fluorouracil Cream, 0.5%321.01.0
Ranibizumab111.01.0
Trametinib101.01.0
Golimumab350.90.9
Ranitidine800.90.9
Fam-Trastuzumab Deruxtecan-Nxki40.90.9
Naproxen Sodium Tablet210.90.9
Crizotinib50.90.9
Dronedarone40.90.9
Bimatoprost110.90.9
Romosozumab-Aqqg50.90.9
Peginterferon Alfa-2A190.80.8
Cetuximab110.80.8
Vemurafenib40.80.8
Ustekinumab340.80.8
Ribavirin210.80.8
Medroxyprogesterone Acetate160.70.7
Rimegepant Sulfate40.70.7
Sofosbuvir60.70.7
Tenofovir Disoproxil Fumarate100.70.7
Dasatinib110.70.7
Onabotulinumtoxina210.60.6
Isotretinoin130.60.6
Tirzepatide350.50.5
Aflibercept60.40.4
Galcanezumab-Gnlm60.40.4
Levonorgestrel340.40.4
Erenumab-Aooe90.40.4
Etonogestrel60.30.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.