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Which drugs are most reported with Psychiatric symptom?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,289 reports · 242 co-occurring drugs

As of the last recalculation, Psychiatric Symptom appears in 7,289 FAERS reports alongside 242 co-occurring drug terms. The strongest observed disproportionality signal is PALIPERIDONE (PRR 9.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Paliperidone	75	9.3	9.3
Brivaracetam	28	8.9	8.9
Valproate Sodium	64	8.9	8.9
Aripiprazole Oral	126	8.8	8.9
Aripiprazole Orally Disintegrating	126	8.8	8.9
Aripiprazole	357	8.7	8.7
Sertraline Hydrochloride	319	8.0	8.0
Valbenazine	69	7.9	7.9
Olanzapine Pamoate	108	7.6	7.7
Pyrazinamide	25	7.6	7.6
Octreotide Acetate	79	7.4	7.5
Olanzapine	270	7.4	7.4
Lithium Carbonate	43	7.3	7.3
Lurasidone Hydrochloride	51	7.0	7.0
Desvenlafaxine Succinate	65	6.9	6.9
Lithium	59	6.7	6.7
Lithium Bromatum	59	6.7	6.7
Venlafaxine Hydrochloride	299	6.7	6.7
Risperidone	285	6.3	6.3
Micafungin Sodium	18	6.1	6.1
Brexpiprazole	35	6.0	6.1
Asenapine Maleate	18	5.9	6.0
Quetiapine Fumarate	60	5.8	5.9
Ziprasidone Mesylate	28	5.6	5.6
Paroxetine Hydrochloride	174	5.6	5.6
Clozapine	237	5.5	5.5
Haloperidol	45	5.3	5.3
Quetiapine	342	5.3	5.3
Carbamazepine	121	5.2	5.2
Haloperidol Lactate	45	5.2	5.2
Lamotirigine	125	5.1	5.1
Lamotrigine Extended-Release	125	5.1	5.1
Lamotrigine Chewable Dispersible	125	5.1	5.1
Zonisamide	26	5.0	5.0
Valproic Acid	55	5.0	5.0
Rotigotine	25	4.9	5.0
Ziprasidone	30	4.9	4.9
Levetiracetam In Sodium Chloride	129	4.8	4.8
Levetiracetam Oral	129	4.8	4.8
Levetiracetam Injection	129	4.8	4.8
Rifampicin	17	4.8	4.8
Finasteride	97	4.6	4.6
Basiliximab	19	4.6	4.6
Varenicline Tartrate	126	4.6	4.6
Acetylcysteine	15	4.6	4.6
Terbinafine Hydrochloride	14	4.5	4.5
Dexamethasone Sodium Phosphate	16	4.5	4.5
Nevirapine	14	4.4	4.4
Pramipexole	23	4.3	4.3
Isoniazid	24	4.2	4.2
Oseltamivir Phosphate	36	4.2	4.2
Suvorexant	19	4.2	4.2
Paliperidone Palmitate	47	4.2	4.2
Paroxetine Hydrochloride Hemihydrate	48	4.1	4.1
Lamotrigine	187	4.1	4.1
Methylphenidate Hydrochloride	85	4.1	4.1
Cenobamate	12	4.1	4.1
Escitslopram	82	4.1	4.1
Paroxetine	48	4.1	4.1
Oxazepam	30	4.0	4.0
Venlafaxine	99	4.0	4.0
Fluoxetine	92	4.0	4.0
Trazodone Hydrochloride	21	3.8	3.8
Valacyclovir Hydrochloride	92	3.8	3.8
Escitalopram Oxalate	95	3.8	3.8
Simvastatin	317	3.7	3.7
Diazepam Oral Solution (Concentrate)	115	3.7	3.7
Diazepam Oral	115	3.7	3.7
Ropinirole	20	3.7	3.7
Lacosamide	48	3.7	3.7
Voriconazole Injection	28	3.7	3.7
Elexacaftor, Tezacaftor, And Ivacaftor	16	3.7	3.7
Levetiracetam	168	3.7	3.7
Lanreotide Acetate	10	3.6	3.6
Clobazam	31	3.6	3.6
Sertraline	140	3.5	3.5
Clonazepam	185	3.4	3.4
Memantine	16	3.3	3.3
Memantine Hydrochloride	16	3.3	3.3
Rasagiline Mesylate	13	3.3	3.3
Fluoxetine Hydrochloride	147	3.3	3.3
Drospirenone And Ethinyl Estradiol	51	3.3	3.3
Voriconazole	35	3.3	3.3
Lisdexamfetamine Dimesylate	38	3.3	3.3
Magnesium Oxide	48	3.3	3.3
Fexofenadine	19	3.3	3.3
Citalopram Hydrobromide	122	3.3	3.3
Diazepam	138	3.3	3.3
Divalproex Sodium	53	3.3	3.3
Montelukast	93	3.2	3.2
Testosterone	26	3.2	3.2
Carisoprodol	21	3.1	3.2
Zinc	27	3.1	3.1
Atomoxetine Hydrochloride	26	3.1	3.1
Zinc Chloride	27	3.1	3.1
Citalopram	146	3.1	3.1
Primidone	11	3.1	3.1
Mirtazapine	98	3.1	3.1
Cariprazine	10	3.1	3.1
Isotretinoin	52	3.0	3.0
Amantadine	16	3.0	3.0
Zinc Gluconate	27	3.0	3.0
Rifampin	15	2.9	2.9
Anakinra	17	2.9	2.9
Eszopiclone	26	2.9	2.9
Guanfacine	8	2.9	2.9
Escitalopram	139	2.9	2.9
Buspirone Hydrochloride	11	2.8	2.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	41	2.8	2.8
Fluticasone Furoate	12	2.8	2.8
Zidovudine	13	2.8	2.8
Lorazepam	172	2.8	2.8
Promethazine Hydrochloride	18	2.8	2.8
Budesonide, Glycopyrrolate, And Formoterol Fumarate	10	2.7	2.7
Rifaximin	20	2.7	2.7
Estradiol Gel 0.1%	43	2.7	2.7
Estradiol Transdermal	43	2.7	2.7
Lubiprostone	9	2.7	2.7
Doxyclycline Hyclate	16	2.7	2.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	33	2.7	2.7
Conjugated Estrogens And Medroxyprogesterone Acetate	22	2.7	2.7
Alprazolam	189	2.7	2.7
Moxifloxacin	13	2.6	2.6
Progesterone	21	2.6	2.6
Topiramate	85	2.6	2.6
Insulin Glargine-Yfgn	20	2.6	2.6
Oxybutynin Chloride	8	2.6	2.6
Oxcarbazepine	29	2.6	2.6
Propranolol Hydrochloride	63	2.5	2.5
Desloratadine	9	2.4	2.4
Loratadine Oral	41	2.4	2.4
Tizanidine Hydrochloride	15	2.4	2.4
Cefazolin Sodium	10	2.4	2.4
Buprenorphine Hydrochloride, Naloxone Hydrochloride	20	2.4	2.4
Levodopa	10	2.4	2.4
Senna Leaf	19	2.4	2.4
Timolol Maleate	8	2.3	2.3
Sennosides	24	2.3	2.3
Anastrozole Tablets	17	2.3	2.3
Raltegravir	13	2.3	2.3
Duloxetine Hydrochloride	146	2.2	2.2
Cefazolin	7	2.2	2.2
Atazanavir	11	2.2	2.2
Sennosides 8.6 Mg Tablets	16	2.2	2.2
Duloxetine	53	2.2	2.2
Senna	16	2.2	2.2
Phenobarbital	11	2.2	2.2
Clarithromycin	26	2.2	2.2
Metronidazole Topical	36	2.2	2.2
Hydromorphone Hydrochloride	69	2.2	2.2
Bupropion Hydrochloride	74	2.2	2.2
Rivastigmine	14	2.1	2.1
Prednisolone	132	2.1	2.1
Prednisolone Oral	132	2.1	2.1
Prednisolone Oral Solution	132	2.1	2.1
Hydroxyzine	35	2.1	2.1
Ribavirin	47	2.1	2.1
Amphetamine	6	2.1	2.1
Palbociclib	68	2.0	2.0
Pravastatin Sodium	14	2.0	2.0
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	2.0	2.0
Fremanezumab-Vfrm	8	2.0	2.0
Vancomycin	40	2.0	2.0
Tamsulosin Hydrochloride	14	2.0	2.0
Esketamine Hydrochloride	12	1.9	1.9
Tizanidine	16	1.9	1.9
Peginterferon Alfa-2A	36	1.9	1.9
Darunavir	10	1.9	1.9
Hydrocodone Bitartrate And Acetaminophen	37	1.9	1.9
Estradiol	56	1.9	1.9
Naltrexone	20	1.9	1.9
Erythropoietin	13	1.8	1.8
Clopidogrel Bisulfate	64	1.8	1.8
Efavirenz	7	1.8	1.8
Norepinephrine Bitartrate	9	1.8	1.8
Pregabalin	168	1.8	1.8
Vancomycin Hydrochloride	41	1.8	1.8
Azelastine	11	1.7	1.8
Losartan	104	1.7	1.7
Modafinil	19	1.7	1.7
Medroxyprogesterone Acetate	29	1.7	1.7
Pancrelipase	22	1.6	1.6
Armodafinil	12	1.6	1.6
Siponimod	5	1.6	1.6
Estrogens, Conjugated	33	1.6	1.6
Oxycodone Hydrochloride	120	1.6	1.6
Methylphenidate	16	1.6	1.6
Conjugated Estrogens	32	1.6	1.6
Carbidopa And Levodopa	26	1.6	1.6
Mirabegron	21	1.6	1.6
Prochlorperazine Maleate	5	1.5	1.6
Nintedanib	17	1.5	1.5
Emtricitabine And Tenofovir Disoproxil Fumarate	24	1.5	1.5
Pimavanserin Tartrate	29	1.5	1.5
Fingolimod Hcl	45	1.5	1.5
Nilotinib	15	1.5	1.5
Dexlansoprazole	21	1.4	1.4
Oseltamivir	4	1.4	1.4
Vibegron	4	1.4	1.4
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	9	1.4	1.4
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	20	1.4	1.4
Ethyl Alcohol	13	1.4	1.4
Vortioxetine	8	1.3	1.3
Mepolizumab	23	1.3	1.3
Fesoterodine Fumarate	5	1.3	1.3
Ruxolitinib	33	1.3	1.3
Brinzolamide	4	1.3	1.3
Deferasirox	12	1.3	1.3
Teriflunomide	20	1.3	1.3
Isopropyl Alcohol	14	1.2	1.2
Belimumab	13	1.2	1.2
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	4	1.1	1.1
Morphine Sulfate	47	1.1	1.1
Peginterferon Beta-1A	5	1.1	1.1
Romosozumab-Aqqg	5	1.1	1.1
Sodium Oxybate	24	1.0	1.0
Sofosbuvir	7	1.0	1.0
Alpelisib	3	1.0	1.0
Sarilumab	9	1.0	1.0
Alcohol	13	1.0	1.0
Daratumumab	13	0.9	0.9
Orlistat	8	0.9	0.9
Axitinib	6	0.9	0.9
Dornase Alfa	6	0.9	0.9
Canagliflozin	9	0.9	0.9
Fam-Trastuzumab Deruxtecan-Nxki	3	0.8	0.8
Sacubitril And Valsartan	34	0.8	0.8
Enzalutamide	17	0.8	0.8
Trifluridine And Tipiracil	3	0.8	0.8
Minoxidil Foam 5% (Womens)	9	0.8	0.8
Leuprolide Acetate	20	0.7	0.7
Diroximel Fumarate	3	0.7	0.7
Etonogestrel	12	0.7	0.7
Olaparib	5	0.7	0.7
Dupilumab	115	0.7	0.7
Natalizumab	43	0.7	0.7
Pirfenidone	9	0.6	0.6
Hydrocodone Bitartrate	9	0.6	0.6
Minoxidil	9	0.6	0.6
Levonorgestrel	39	0.6	0.6
Galcanezumab-Gnlm	5	0.5	0.5
Copper	5	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.