Reaction

Type 1 Diabetes Mellitus reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,931 reports · 221 co-occurring drugs

As of the last recalculation, Type 1 Diabetes Mellitus appears in 5,931 FAERS reports alongside 221 co-occurring drug terms. The strongest observed disproportionality signal is ZIPRASIDONE MESYLATE (PRR 34.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ziprasidone Mesylate	137	34.5	34.8
Olanzapine Pamoate	341	31.0	31.2
Ipilimumab	354	30.5	30.8
Ziprasidone	139	28.3	28.6
Nivolumab	662	26.9	27.1
Pembrolizumab	708	26.7	26.9
Divalproex Sodium	216	16.9	16.9
Quetiapine	803	16.8	16.8
Atezolizumab	177	16.5	16.5
Olanzapine	420	14.7	14.7
Daspone	39	14.1	14.2
Dapsone Gel, 5%	39	14.1	14.2
Lithium Carbonate	65	13.6	13.6
Human Insulin	47	13.3	13.4
Dapsone	39	12.9	12.9
Lenvatinib	110	12.0	12.0
Durvalumab	66	11.5	11.5
Risperidone	356	9.9	10.0
Trazodone Hydrochloride	42	9.5	9.5
Pemetrexed	55	9.1	9.1
Insulin	141	9.1	9.1
Aripiprazole	268	8.0	8.0
Glyburide	45	6.6	6.6
Insulin Aspart	120	6.5	6.5
Insulin Human	71	6.3	6.3
Pancrelipase	67	6.2	6.2
Diphenhydramine Hcl	19	6.0	6.0
Pemetrexed Disodium	64	5.9	6.0
Pioglitazone	72	5.9	5.9
Enalapril Maleate	40	5.7	5.7
Basiliximab	19	5.7	5.7
Axitinib	31	5.6	5.6
Gemfibrozil	24	5.6	5.6
Lithium	39	5.5	5.5
Lithium Bromatum	39	5.5	5.5
Diphenhydramine Hydrochloride Capsule, Liquid Filled	33	5.4	5.5
Minocycline	18	5.4	5.4
Temazepam	56	5.3	5.3
Bupropion Hydrochloride	141	5.1	5.1
Oxcarbazepine	46	5.0	5.0
Insulin Degludec	33	5.0	5.0
Ezetimibe And Simvastatin	21	4.9	4.9
Glipizide	83	4.8	4.8
Insulin Glargine-Yfgn	30	4.8	4.8
Sertraline Hydrochloride	159	4.8	4.8
Paclitaxel (Aibumin-Bound)	108	4.7	4.7
Extended Phenytoin Sodium	22	4.6	4.6
Carisoprodol	25	4.6	4.6
Insulin Lispro	175	4.5	4.6
Paroxetine Hydrochloride	115	4.5	4.5
Insulin Glulisine	13	4.5	4.5
Febuxostat Tablets 40 Mg	13	4.5	4.5
Febuxostat Tablets 80 Mg	13	4.5	4.5
Methimazole	10	4.5	4.5
Buspirone Hydrochloride	14	4.5	4.5
Clonazepam	197	4.4	4.4
Carboplatin	155	4.4	4.4
Paclitaxel	121	4.4	4.4
Belimumab	39	4.3	4.3
Zonisamide	18	4.3	4.3
Meperidine Hydrochloride	11	4.2	4.2
Insulin Glargine	284	4.2	4.2
Amlodipine Besylate And Benazepril Hydrochloride	11	4.2	4.2
Venlafaxine Hydrochloride	153	4.1	4.1
Methylprednisolone Sodium Succinate	54	4.1	4.1
Haloperidol	28	4.1	4.1
Zolpidem Tartrate	151	4.0	4.0
Haloperidol Lactate	28	4.0	4.0
Zidovudine	15	3.9	3.9
Hyoscyamine Sulfate	10	3.8	3.8
Sitagliptin And Metformin Hydrochloride	23	3.8	3.8
Pegaspargase	13	3.7	3.7
Fluoxetine Hydrochloride	133	3.7	3.7
Chlorthalidone	12	3.6	3.6
Mirtazapine	93	3.6	3.6
Valproic Acid	32	3.6	3.6
Nitroglycerin	53	3.5	3.5
Sitagliptin	71	3.5	3.5
Ketoprofen	13	3.5	3.5
Efavirenz	11	3.5	3.5
Hydroxychloroquine	73	3.5	3.5
Indomethacin	13	3.4	3.5
Metformin Hcl	54	3.4	3.4
Clonidine	50	3.4	3.4
Levothyroxine Sodium Anhydrous	97	3.4	3.4
Escitalopram	135	3.4	3.4
Lorazepam	171	3.4	3.4
Promethazine Hydrochloride	18	3.4	3.4
Docusate Sodium - Sennosides	31	3.4	3.4
Meclizine Hcl 12.5Mg	13	3.4	3.4
Meclizine Hcl 25Mg	13	3.4	3.4
Meclizine Hcl 12.5 Mg	13	3.4	3.4
Meclizine Hcl 25 Mg	13	3.4	3.4
Mycophenolate Mofetil	124	3.3	3.3
Mycophenolate Mofetil Hydrochloride	124	3.2	3.2
Somatropin	67	3.2	3.2
Paliperidone	21	3.2	3.2
Isotretinoin	44	3.1	3.1
Bevacizumab	109	3.1	3.1
Ganciclovir	9	3.1	3.1
Irbesartan	39	3.1	3.1
Anti-Itch	58	3.1	3.1
Anti-Pruritic	58	3.1	3.1
Antipruritic (Anti-Itch)	58	3.1	3.1
Cool Relief Gel With Aloe	58	3.1	3.1
Drs. Hydrocortisone	58	3.1	3.1
Hydrocortisone Continuous Spray	58	3.1	3.1
Hydrocortisone Spray	58	3.1	3.1
Anti-Itch Cream	58	3.1	3.1
Hydrocortisone Lotion	58	3.1	3.1
Hydrocortisone Cream 1%	58	3.1	3.1
Hydrocortisone Cream 1/2%	58	3.1	3.1
Azathioprine	76	3.1	3.1
Hydrocortisone 1%	58	3.1	3.1
Anti-Thymocyte Globulin (Rabbit)	7	3.0	3.0
Eszopiclone	22	3.0	3.0
Fexofenadine Hcl	8	3.0	3.0
Ranolazine	9	3.0	3.0
Ganciclovir Sodium	9	3.0	3.0
Raltegravir	14	3.0	3.0
Febuxostat	14	2.9	2.9
Docusate Sodium	48	2.9	2.9
Atorvastatin Calcium	202	2.9	2.9
Lovastatin	21	2.9	2.9
Methylphenidate Hydrochloride	48	2.9	2.9
Citalopram	110	2.9	2.9
Carbamazepine	54	2.8	2.8
Amphotericin B	10	2.8	2.8
Meclizine	13	2.8	2.8
Lisinopril And Hydrochlorothiazide	8	2.7	2.8
Magnesium Oxide	32	2.7	2.7
Pantoprazole Sodium	112	2.7	2.7
Diroximel Fumarate	9	2.7	2.7
Guaifenesin	23	2.7	2.7
Ivacaftor	6	2.7	2.7
Methocarbamol	17	2.6	2.6
Topiramate	69	2.6	2.6
Alprazolam	151	2.6	2.6
Lisinopril	222	2.6	2.6
Leflunomide	77	2.6	2.6
Valsartan And Hydrochlorothiazide	10	2.6	2.6
Prednisolone	131	2.6	2.6
Prednisolone Oral	131	2.6	2.6
Prednisolone Oral Solution	131	2.6	2.6
Nicotine Polacrilex Mini	11	2.6	2.6
Nicotine Polarilex	11	2.6	2.6
Ursosiol	14	2.5	2.5
Hydroxychloroquine Sulfate	65	2.5	2.5
Ezetimibe	53	2.5	2.5
Esomeprazole Magnesium	162	2.5	2.5
Ribavirin	45	2.5	2.5
Atazanavir	10	2.4	2.4
Tenofovir Disoproxil Fumarate Tablets	6	2.4	2.4
Ursodiol	15	2.4	2.4
Alpelisib	6	2.4	2.4
Gabapentin	243	2.4	2.4
Lansoprazole	119	2.4	2.4
Atomoxetine Hydrochloride	16	2.4	2.4
Tacrolimus	104	2.4	2.4
Granisetron	7	2.3	2.3
Simvastatin	163	2.3	2.3
Everolimus Tablets	11	2.3	2.3
Aripiprazole Oral	27	2.3	2.3
Aripiprazole Orally Disintegrating	27	2.3	2.3
Lamivudine	20	2.3	2.3
Cisplatin	50	2.3	2.3
Guanfacine	5	2.2	2.2
Amlodipine Besylate And Valsartan	7	2.2	2.2
Peginterferon Alfa-2A	34	2.2	2.2
Clozapine	77	2.2	2.2
Tacrolimus Ointment 0.1%	76	2.2	2.2
Olmesartan Medoxomil	22	2.2	2.2
Tacrolimus Extended-Release Capsules	76	2.2	2.2
Sevelamer Carbonate	7	2.1	2.1
Lamivudine Oral	15	2.1	2.1
Estrogens, Conjugated	35	2.1	2.1
Conjugated Estrogens	34	2.1	2.1
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	2.0	2.0
Lumacaftor And Ivacaftor	5	2.0	2.0
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	2.0	2.0
Granisetron Hydrochloride	6	2.0	2.0
Dabrafenib	12	2.0	2.0
Levocetirizine Dihydrochloride	13	1.9	1.9
Dapagliflozin	17	1.9	1.9
Trametinib	13	1.9	1.9
Cyclophosphamide Injection, Solution	88	1.8	1.8
Cyclophosphamide	88	1.8	1.8
Cyclophosphamide For Injection	88	1.8	1.8
Exenatide	26	1.7	1.7
Brentuximab Vedotin	5	1.7	1.7
Elexacaftor, Tezacaftor, And Ivacaftor	6	1.7	1.7
Rifaximin	10	1.7	1.7
Empagliflozin	32	1.7	1.7
Dimethyl Fumarate	57	1.6	1.6
Etoposide	34	1.6	1.6
Omalizumab	39	1.6	1.6
Interferon Beta-1A	88	1.6	1.6
Peginterferon Beta-1A	6	1.6	1.6
Gemcitabine	18	1.6	1.6
Lisdexamfetamine Dimesylate	15	1.6	1.6
Brivaracetam	4	1.6	1.6
Liraglutide	21	1.5	1.5
Oxaliplatin	30	1.4	1.4
Emicizumab	5	1.4	1.4
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.4	1.4
Gemcitabine Hydrochloride	20	1.3	1.3
Cabozantinib	18	1.3	1.3
Alirocumab	9	1.3	1.3
Dornase Alfa	7	1.3	1.3
Paricalcitol	5	1.2	1.2
Oral Semaglutide	25	1.2	1.2
Olaparib	7	1.2	1.2
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	6	1.2	1.2
Hydrocodone Bitartrate And Acetaminophen	17	1.1	1.1
Varenicline Tartrate	22	1.0	1.0
Drospirenone And Ethinyl Estradiol	11	0.9	0.9
Natalizumab	40	0.8	0.8
Dulaglutide	19	0.8	0.8
Minoxidil Foam 5% (Womens)	7	0.7	0.7
Guselkumab	6	0.6	0.6
Minoxidil	7	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.