Reaction

Immune Effector Cell-Associated Neurotoxicity Syndrome reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,544 reports · 147 co-occurring drugs

As of the last recalculation, Immune Effector Cell-Associated Neurotoxicity Syndrome appears in 5,544 FAERS reports alongside 147 co-occurring drug terms. The strongest observed disproportionality signal is AXICABTAGENE CILOLEUCEL (PRR 1,255.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Axicabtagene Ciloleucel	2,069	1,255.2	1,590.3
Fludarabine Phosphate	808	90.1	92.0
Blinatumomab	219	82.0	83.7
Polatuzumab Vedotin	107	42.0	42.4
Anakinra	162	37.7	38.1
Bendamustine Hcl	123	30.4	30.7
Cyclophosphamide Injection, Solution	979	25.0	25.1
Cyclophosphamide	979	25.0	25.1
Cyclophosphamide For Injection	979	25.0	25.1
Atovaquone	52	24.5	24.6
Cefepime Hydrochloride	98	23.2	23.4
Cefepime	85	22.6	22.7
Posaconazole Delayed-Release	63	21.8	21.9
Magnesium Sulfate In Water For	71	21.1	21.2
Magnesium Sulfate Heptahydrate	71	20.7	20.8
Magnesium Sulfate	71	20.7	20.8
Obinutuzumab	86	19.9	20.0
Posaconazole	82	19.2	19.3
Valacyclovir	205	19.1	19.2
Ifosfamide	102	18.1	18.2
Mesna	40	18.0	18.0
Mesna Injection	39	17.8	17.9
Micafungin Sodium	39	17.4	17.5
Meropenem	128	15.3	15.4
Tocilizumab	405	14.3	14.3
Cytarabine	219	14.2	14.3
Piperacillin Sodium,Tazobactam Sodium	95	13.7	13.7
Levetiracetam In Sodium Chloride	266	13.5	13.5
Levetiracetam Oral	266	13.5	13.5
Levetiracetam Injection	266	13.5	13.5
Piperacillin And Tazobactam	45	13.3	13.4
Piperacillin Sodium And Tazobactam Sodium	68	13.2	13.2
Norepinephrine	36	12.7	12.8
Valacyclovir Hydrochloride	224	12.4	12.4
Dexamethasone Sodium Phosphate	33	12.3	12.3
Levetiracetam	389	11.7	11.7
Norepinephrine Bitartrate	42	11.0	11.1
Doxorubicin	249	10.9	11.0
Acyclovir	305	10.6	10.6
Gemcitabine	108	10.5	10.5
Filgrastim	101	10.2	10.3
Fluconazole	167	9.2	9.2
Selinexor	21	9.1	9.2
Gemcitabine Hydrochloride	124	9.0	9.0
Prochlorperazine	62	8.5	8.5
Dexamethasone 1.5 Mg	585	8.3	8.3
Amikacin	37	8.2	8.2
Dexamethasone	584	8.1	8.2
Etoposide	155	8.1	8.1
Oxaliplatin	155	8.0	8.1
Rituximab	416	7.9	7.9
Ganciclovir	20	7.4	7.4
Carfilzomib	54	7.2	7.2
Ganciclovir Sodium	20	7.1	7.1
Phytonadione	16	7.1	7.1
Doxorubicin Hydrochloride	61	7.1	7.1
Febuxostat Tablets 40 Mg	19	7.0	7.0
Febuxostat Tablets 80 Mg	19	7.0	7.0
Vancomycin	105	6.9	6.9
Calcium Gluconate	22	6.9	6.9
Vincristine Sulfate	52	6.7	6.7
Bendamustine Hydrochloride	21	6.6	6.6
Vancomycin Hydrochloride	113	6.5	6.6
Daptomycin	16	6.5	6.5
Sulfamethoxazole And Trimethoprim	137	6.2	6.2
Leucovorin Calcium	31	6.1	6.1
Thiotepa	15	5.9	5.9
Granisetron Hydrochloride	16	5.8	5.8
Polyethylene Glycol	16	5.6	5.6
Ondansetron	158	5.6	5.6
Ondansetron Tablets	158	5.6	5.6
Instalax Polyethylene Glycol 3350	18	5.5	5.5
Polyethylene Glycol 400	18	5.3	5.3
Ondansetron Hydrochloride	165	5.2	5.2
Diphenhydramine	86	5.2	5.2
Rocuronium Bromide	16	5.1	5.1
Ursosiol	26	5.0	5.0
Granisetron	14	5.0	5.0
Methylprednisolone	180	5.0	5.0
Cisplatin	102	5.0	5.0
Levofloxacin	78	4.9	4.9
Levofloxacin In 5% Dextrose	78	4.9	4.9
Sodium Chloride Tablet	91	4.7	4.7
Sodium Chloride Tablets	91	4.7	4.7
Metoclopramide	68	4.7	4.7
Midazolam	31	4.6	4.6
Valganciclovir Hydrochloride Powder,	15	4.6	4.6
Sodium Chloride	96	4.6	4.6
Ursodiol	26	4.5	4.5
Midazolam Hydrochloride	32	4.5	4.5
Gentamicin	15	4.3	4.3
Dextrose	15	4.3	4.3
Febuxostat	19	4.3	4.3
Alteplase	17	4.3	4.3
Dextrose Monohydrate	15	4.2	4.2
Potassium Chloride, Dextrose Monohydrate	101	4.2	4.2
Potassium Chloride Oral	101	4.2	4.2
Potassium Chloride Extended-Release	101	4.1	4.2
Allopurinol	167	4.1	4.1
Daratumumab	43	4.1	4.1
Valganciclovir	20	4.0	4.0
Valganciclovir Hydrochloride	20	4.0	4.0
Voriconazole Injection	23	4.0	4.0
Acetaminophen Tablet Extended Release	253	3.9	3.9
Pain Reliever	253	3.9	3.9
Acetaminophen 500Mg	253	3.9	3.9
Linezolid	30	3.8	3.8
Pyrazinamide	9	3.6	3.6
Amphotericin B	12	3.6	3.6
Gentamicin Sulfate	15	3.6	3.6
Sodium Bicarbonate	22	3.6	3.6
Sodium Bicarbonate Injection,	22	3.6	3.6
Ceftriaxone Sodium	36	3.5	3.5
Metoclopramide Hydrochloride	72	3.5	3.5
Melphalan	21	3.5	3.5
Potassium Chloride	102	3.4	3.4
Melphalan Hydrochloride	22	3.3	3.3
Entecavir	10	3.2	3.2
Sucralfate Oral	12	3.2	3.2
Sucralfate Oral Suspension	12	3.2	3.2
Ceftriaxone	27	3.1	3.1
Insulin Glargine-Yfgn	18	3.1	3.1
Ibrutinib	64	3.0	3.0
Voriconazole	24	3.0	3.0
Rifampin	11	2.8	2.8
Acalabrutinib	9	2.8	2.8
Everolimus Tablets	11	2.5	2.5
Fosaprepitant Dimeglumine	9	2.5	2.5
Heparin Sodium	9	2.5	2.5
Carboplatin	82	2.4	2.4
Isoniazid	10	2.3	2.3
Iohexol	5	2.3	2.3
Apixaban	40	2.3	2.3
Aprepitant	11	2.2	2.2
Propofol	20	2.1	2.1
Busulfan	8	1.9	1.9
Bortezomib	45	1.9	1.9
Venetoclax	31	1.9	1.9
Remdesivir	6	1.7	1.7
Dapagliflozin	13	1.6	1.6
Pomalidomide	42	1.5	1.5
Temozolomide	8	1.4	1.4
Vibegron	3	1.4	1.4
Romiplostim	5	1.2	1.2
Eltrombopag Olamine	7	1.1	1.1
Lenalidomide	95	0.8	0.8
Pegfilgrastim	16	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.