Reaction

Granulocytopenia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,668 reports · 158 co-occurring drugs

As of the last recalculation, Granulocytopenia appears in 5,668 FAERS reports alongside 158 co-occurring drug terms. The strongest observed disproportionality signal is CLOZAPINE (PRR 141.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Clozapine	2,616	141.2	144.2
Valproate Sodium	204	37.6	37.9
Divalproex Sodium	371	31.3	31.5
Lithium Carbonate	80	17.5	17.6
Lithium	102	15.1	15.2
Lithium Bromatum	102	15.1	15.2
Haloperidol	92	14.1	14.2
Haloperidol Lactate	93	14.0	14.1
Gemfibrozil	50	12.2	12.2
Dextrose Monohydrate	42	11.6	11.7
Olanzapine Pamoate	125	11.4	11.5
Docusate Sodium 100Mg	65	10.1	10.1
Dextrose	33	9.3	9.3
Ziprasidone Mesylate	35	9.1	9.1
Mesna Injection	20	8.9	8.9
Olanzapine	250	8.9	8.9
Mesna	20	8.8	8.8
Azacitidine For	41	8.3	8.3
Ziprasidone	38	8.0	8.0
Docusate Sodium	121	7.8	7.9
Sodium Chloride Tablet	134	6.8	6.8
Sodium Chloride Tablets	134	6.8	6.8
Oxcarbazepine	57	6.5	6.5
Docusate Sodium - Sennosides	56	6.4	6.4
Sodium Chloride	134	6.4	6.4
Azacitidine	49	6.1	6.1
Zidovudine	21	5.8	5.8
Filgrastim	58	5.7	5.7
Buspirone Hydrochloride	17	5.7	5.7
Cytarabine	91	5.6	5.6
Risperidone	197	5.6	5.6
Quetiapine Fumarate	44	5.5	5.5
Atropine Sulfate	16	5.5	5.5
Irinotecan Hydrochloride	19	5.4	5.4
Bleomycin Sulfate	15	5.3	5.4
Ribociclib	45	5.3	5.3
Cyclophosphamide Injection, Solution	242	5.2	5.2
Cyclophosphamide	242	5.2	5.2
Cyclophosphamide For Injection	242	5.2	5.2
Pemetrexed	30	5.2	5.2
Polyethylene Glycol	15	5.1	5.1
Clonazepam	215	5.1	5.1
Fulvestrant	45	5.0	5.0
Docetaxel Anhydrous	88	4.9	4.9
Docetaxel	88	4.9	4.9
Bisacodyl Suppositories	17	4.8	4.8
Venetoclax	80	4.8	4.8
Biscodyl	17	4.8	4.8
Dexamethasone Sodium Phosphate	13	4.7	4.7
Valproic Acid	40	4.7	4.7
Ganciclovir	13	4.7	4.7
Aripiprazole Oral	52	4.7	4.7
Aripiprazole Orally Disintegrating	52	4.7	4.7
Lorazepam	219	4.6	4.6
Etoposide	90	4.6	4.6
Ganciclovir Sodium	13	4.5	4.5
Bisacodyl	17	4.4	4.4
Vincristine Sulfate	35	4.4	4.4
Doxorubicin Hydrochloride	38	4.3	4.3
Ifosfamide	25	4.3	4.3
Quetiapine	217	4.3	4.3
Cisplatin	89	4.2	4.2
Aripiprazole	136	4.2	4.2
Propranolol Hydrochloride	76	3.9	3.9
Fludarabine Phosphate	41	3.8	3.9
Doxorubicin	92	3.8	3.8
Paliperidone	24	3.8	3.8
Oxybutynin Chloride	9	3.8	3.8
Lactulose	39	3.8	3.8
Busulfan	16	3.7	3.7
Zonisamide	15	3.7	3.7
Enalapril Maleate	25	3.7	3.7
Fluorouracil Cream, 0.5%	76	3.7	3.7
Paclitaxel (Aibumin-Bound)	81	3.7	3.7
Fluorouracil	76	3.6	3.6
Pemetrexed Disodium	37	3.6	3.6
Atropine	8	3.5	3.6
Standardized Senna Concentrate	12	3.5	3.5
Micafungin Sodium	8	3.5	3.5
Leucovorin Calcium	18	3.5	3.5
Asenapine Maleate	8	3.4	3.4
Loratadine Oral	45	3.4	3.4
Carboplatin	115	3.4	3.4
Paclitaxel	88	3.3	3.3
Trazodone Hydrochloride	14	3.3	3.3
Methimazole	7	3.3	3.3
Levothyroxine Sodium Anhydrous	88	3.3	3.3
Cefuroxime	10	3.2	3.2
Cetuximab	27	3.2	3.2
Lurasidone Hydrochloride	18	3.2	3.2
Obinutuzumab	14	3.1	3.1
Temazepam	32	3.1	3.1
Thiotepa	8	3.1	3.1
Panitumumab	13	3.1	3.1
Calcium Gluconate	10	3.1	3.1
Metformin Hcl	45	3.0	3.0
Meropenem	26	3.0	3.0
Pertuzumab	22	3.0	3.0
Carbamazepine	53	2.9	2.9
Tolterodine Tartrate	7	2.9	2.9
Lamotrigine	98	2.8	2.8
Mercaptopurine	13	2.8	2.8
Cefazolin Sodium	9	2.7	2.7
Vancomycin Hydrochloride	48	2.7	2.7
Phenytoin	15	2.6	2.6
Trastuzumab	49	2.6	2.6
Sennosides 8.6 Mg Tablets	15	2.6	2.6
Piperacillin Sodium And Tazobactam Sodium	14	2.6	2.6
Lamivudine	22	2.6	2.6
Senna	15	2.6	2.6
Bendamustine Hcl	11	2.6	2.6
Letrozole Tablets	34	2.6	2.6
Eltrombopag Olamine	16	2.6	2.6
Topiramate	64	2.5	2.5
Gentamicin	9	2.5	2.5
Peginterferon Alfa-2A	37	2.5	2.5
Entecavir	8	2.5	2.5
Granisetron Hydrochloride	7	2.5	2.5
Bendamustine Hydrochloride	8	2.5	2.5
Extended Phenytoin Sodium	11	2.4	2.4
Donepezil Hydrochloride	24	2.4	2.4
Melphalan Hydrochloride	16	2.3	2.3
Gemcitabine	25	2.3	2.3
Guanfacine	5	2.3	2.3
Rituximab	132	2.3	2.3
Efavirenz	7	2.3	2.3
Gemcitabine Hydrochloride	33	2.3	2.3
Letrozole	38	2.3	2.3
Melphalan	14	2.3	2.3
Polatuzumab Vedotin	6	2.3	2.3
Vancomycin	35	2.2	2.2
Rifampicin	6	2.2	2.2
Pitavastatin Calcium	6	2.2	2.2
Capecitabine	53	2.1	2.1
Oxaliplatin	43	2.1	2.1
Oxybutynin	17	2.1	2.1
Granisetron	6	2.1	2.1
Pyrazinamide	5	2.0	2.0
Cladribine	5	1.9	1.9
Carbidopa And Levodopa	24	1.9	1.9
Glipizide	30	1.8	1.8
Durvalumab	10	1.8	1.8
Pegaspargase	6	1.8	1.8
Bevacizumab	60	1.8	1.8
Blinatumomab	5	1.8	1.8
Temozolomide	10	1.7	1.7
Ribavirin	30	1.7	1.7
Axicabtagene Ciloleucel	4	1.5	1.5
Palbociclib	37	1.4	1.4
Paliperidone Palmitate	12	1.4	1.4
Trifluridine And Tipiracil	4	1.4	1.4
Ranitidine Hydrochloride	20	1.4	1.4
Apalutamide	4	1.2	1.2
Gefitinib	3	1.2	1.2
Lapatinib	5	1.2	1.2
Carfilzomib	9	1.2	1.2
Suvorexant	4	1.1	1.1
Sofosbuvir	6	1.1	1.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.