Reaction

Incoherent reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,410 reports · 258 co-occurring drugs

As of the last recalculation, Incoherent appears in 6,410 FAERS reports alongside 258 co-occurring drug terms. The strongest observed disproportionality signal is RIVASTIGMINE (PRR 10.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Rivastigmine	59	10.3	10.3
Pimavanserin Tartrate	128	7.6	7.7
Standardized Senna Concentrate	29	7.5	7.5
Dalteparin Sodium	24	7.4	7.4
Rasagiline Mesylate	25	7.3	7.3
Methadone Hydrochloride	24	7.2	7.2
Extended Phenytoin Sodium	37	7.2	7.2
Amantadine	31	6.5	6.5
Memantine	26	6.2	6.2
Memantine Hydrochloride	26	6.2	6.2
Lithium Carbonate	30	5.8	5.8
Primidone	18	5.8	5.8
Donepezil Hydrochloride	60	5.4	5.4
Sodium Oxybate	106	5.3	5.3
Ethyl Alcohol	44	5.3	5.3
Zolpidem Tartrate	214	5.3	5.3
Phenytoin	33	5.2	5.2
Olanzapine Pamoate	64	5.1	5.1
Morphine	112	4.9	4.9
Calcium, Magnesium, Potassium, And Sodium Oxybates	13	4.9	4.9
Isopropyl Alcohol	50	4.8	4.8
Carbidopa And Levodopa	70	4.8	4.8
Baclofen	126	4.8	4.8
Haloperidol Lactate	36	4.7	4.7
Divalproex Sodium	67	4.7	4.7
Risperidone	185	4.6	4.6
Carisoprodol	27	4.6	4.6
Quetiapine	262	4.6	4.6
Paroxetine Hydrochloride Hemihydrate	46	4.5	4.5
Haloperidol	33	4.4	4.4
Paroxetine Hydrochloride	122	4.4	4.4
Paroxetine	46	4.4	4.4
Mirtazapine	122	4.4	4.4
Diazepam	161	4.4	4.4
Buprenorphine Hydrochloride, Naloxone Hydrochloride	32	4.3	4.3
Paliperidone Palmitate	42	4.3	4.3
Diazepam Oral Solution (Concentrate)	113	4.2	4.2
Diazepam Oral	113	4.2	4.2
Alcohol	49	4.1	4.1
Interferon Beta-1B	24	4.1	4.1
Siponimod	11	4.0	4.0
Methadone	52	4.0	4.0
Tizanidine Hydrochloride	22	4.0	4.0
Oxazepam	26	3.9	3.9
Oseltamivir Phosphate	29	3.9	3.9
Clonazepam	185	3.8	3.8
Lithium	29	3.7	3.8
Lithium Bromatum	29	3.7	3.8
Lactulose	44	3.7	3.7
Modafinil	37	3.7	3.7
Liothyronine Sodium	10	3.7	3.7
Captopril	11	3.7	3.7
Lorazepam	199	3.7	3.7
Olanzapine	120	3.7	3.7
Venlafaxine Hydrochloride	146	3.6	3.6
Niacin	13	3.6	3.6
Valproic Acid	35	3.6	3.6
Carbamazepine	74	3.6	3.6
Rotigotine	16	3.6	3.6
Quetiapine Fumarate	32	3.5	3.5
Ziprasidone	19	3.5	3.5
Cenobamate	9	3.5	3.5
Promethazine Hydrochloride	20	3.5	3.5
Diphenhydramine Hcl	12	3.5	3.5
Isosorbide Mononitrate	22	3.5	3.5
Ziprasidone Mesylate	15	3.4	3.4
Ropinirole	16	3.4	3.4
Oxybutynin Chloride	9	3.3	3.3
Diphenoxylate Hydrochloride And Atropine Sulfate	14	3.3	3.3
Temazepam	38	3.3	3.3
Suvorexant	13	3.3	3.3
Alprazolam	201	3.2	3.2
Levodopa	12	3.2	3.2
Meperidine Hydrochloride	9	3.2	3.2
Venlafaxine	69	3.2	3.2
Citalopram Hydrobromide	101	3.1	3.1
Armodafinil	20	3.1	3.1
Regorafenib	11	3.1	3.1
Fentanyl	92	3.1	3.1
Topiramate	87	3.1	3.1
Droxidopa	20	3.0	3.0
Clozapine	115	3.0	3.0
Oxybutynin	27	3.0	3.0
Asenapine Maleate	8	3.0	3.0
Sertraline Hydrochloride	107	3.0	3.0
Eszopiclone	23	2.9	2.9
Methylphenidate Hydrochloride	53	2.9	2.9
Citalopram	121	2.9	2.9
Dorzolamide Hydrochloride And Timolol Maleate	7	2.9	2.9
Meclizine Hcl 12.5Mg	12	2.9	2.9
Meclizine Hcl 25Mg	12	2.9	2.9
Meclizine Hcl 12.5 Mg	12	2.9	2.9
Meclizine Hcl 25 Mg	12	2.9	2.9
Sorafenib	18	2.8	2.8
Rifaximin	18	2.8	2.8
Meclizine	14	2.8	2.8
Insulin Human	34	2.8	2.8
Temozolomide	18	2.8	2.8
Gabapentin	301	2.8	2.8
Atropine	7	2.7	2.7
Butalbital, Acetaminophen, And Caffeine	9	2.7	2.7
Morphine Sulfate	101	2.7	2.7
Pregabalin	223	2.7	2.7
Atropine Sulfate	9	2.7	2.7
Insulin	46	2.7	2.7
Naltrexone Hydrochloride And Bupropion Hydrochloride	7	2.7	2.7
Interferon Beta-1A	156	2.7	2.7
Meclizine Hydrochloride	16	2.7	2.7
Clonidine	41	2.6	2.6
Levetiracetam	106	2.6	2.6
Valacyclovir Hydrochloride	56	2.6	2.6
Propranolol Hydrochloride	57	2.6	2.6
Methocarbamol	18	2.6	2.6
Doxepin Hydrochloride	10	2.6	2.6
Doxepin	8	2.6	2.6
Nitrofurantoin	13	2.6	2.6
Escitalopram	109	2.5	2.6
Nitrofurantoin (Monohydrate/Macrocrystals)	13	2.5	2.5
Methocarbamol Tablets	13	2.5	2.5
Valproate Sodium	16	2.5	2.5
Melatonin	42	2.5	2.5
Lamotrigine	101	2.5	2.5
Lamotirigine	55	2.5	2.5
Lamotrigine Extended-Release	55	2.5	2.5
Lamotrigine Chewable Dispersible	55	2.5	2.5
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	27	2.5	2.5
Vilazodone Hydrochloride	7	2.5	2.5
Fluoxetine Hydrochloride	96	2.5	2.5
Amlodipine Besylate And Benazepril Hydrochloride	7	2.5	2.5
Oxycodone And Acetaminophen Tablets	9	2.5	2.5
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	31	2.4	2.4
Digoxin	53	2.4	2.4
Hydroxyzine	35	2.4	2.4
Bupropion Hydrochloride	72	2.4	2.4
Mesna Injection	6	2.4	2.4
Metformin Hcl	40	2.4	2.4
Escitslopram	42	2.4	2.4
Brexpiprazole	12	2.3	2.4
Valbenazine	18	2.3	2.3
Atomoxetine Hydrochloride	17	2.3	2.3
Insulin Aspart	47	2.3	2.3
Propofol	26	2.3	2.3
Mesna	6	2.3	2.3
Sertraline	83	2.3	2.3
Atenolol	93	2.3	2.3
Lovastatin	18	2.3	2.3
Salmeterol Xinafoate	6	2.3	2.3
Phenobarbital	10	2.2	2.2
Rizatriptan Benzoate	7	2.2	2.2
Minocycline	8	2.2	2.2
Naltrexone	21	2.2	2.2
Insulin Lispro	93	2.2	2.2
Ketoconazole Foam	10	2.2	2.2
Zonisamide	10	2.2	2.2
Labetalol	9	2.2	2.2
Escitalopram Oxalate	49	2.2	2.2
Ketoconazole Cream, 2%	10	2.2	2.2
Tizanidine	16	2.2	2.2
Indapamide	12	2.2	2.2
Lisdexamfetamine Dimesylate	22	2.2	2.2
Sotalol Hydrochloride	11	2.1	2.2
Rabeprazole Sodium	18	2.1	2.1
Glipizide	40	2.1	2.1
Methylphenidate	19	2.1	2.1
Aripiprazole	79	2.1	2.1
Oxycodone Hydrochloride	139	2.1	2.1
Instalax Polyethylene Glycol 3350	8	2.1	2.1
Duloxetine Hydrochloride	120	2.1	2.1
Paliperidone	15	2.1	2.1
Human Insulin	8	2.1	2.1
Guanfacine	5	2.1	2.1
Levetiracetam In Sodium Chloride	49	2.1	2.1
Levetiracetam Oral	49	2.1	2.1
Levetiracetam Injection	49	2.1	2.1
Quinapril Hydrochloride	5	2.1	2.1
Polyethylene Glycol 400	8	2.0	2.1
Oseltamivir	5	2.0	2.0
Warfarin Sodium	29	2.0	2.0
Derma Foam Excel Hand Sanitizer	5	2.0	2.0
Ribavirin	40	2.0	2.0
Ethanol	5	2.0	2.0
Loratadine Oral	30	2.0	2.0
Peginterferon Beta-1A	8	2.0	2.0
Amphetamine	5	2.0	2.0
Insulin Glulisine	6	1.9	1.9
Oxcarbazepine	19	1.9	1.9
Lenvatinib	19	1.9	1.9
Timolol	7	1.9	1.9
Oxycodone Hydrochloride And Acetaminophen	57	1.9	1.9
Hydromorphone Hydrochloride	53	1.9	1.9
Buprenorphine	53	1.9	1.9
Lurasidone Hydrochloride	12	1.9	1.9
Tapentadol Hydrochloride	19	1.8	1.8
Natalizumab	102	1.8	1.8
Voriconazole	17	1.8	1.8
Oxycodone And Acetaminophen	13	1.8	1.8
Voriconazole Injection	12	1.8	1.8
Exenatide	29	1.8	1.8
Prochlorperazine Maleate	5	1.8	1.8
Amlodipine Besylate And Valsartan	6	1.8	1.8
Agalsidase Beta	5	1.8	1.8
Peginterferon Alfa-2A	29	1.7	1.7
Epoprostenol	7	1.7	1.7
Sevelamer Carbonate	6	1.7	1.7
Desvenlafaxine Succinate	14	1.7	1.7
Naproxen Sodium Tablet, Coated	7	1.7	1.7
Naproxen Sodium, Coated Tablets	7	1.7	1.7
Naproxen Sodium 220Mg	7	1.7	1.7
Brimonidine Tartrate	9	1.6	1.6
Fentanyl Citrate	9	1.6	1.6
Selexipag	13	1.6	1.6
Insulin Glargine	120	1.6	1.6
Hydrocodone Bitartrate And Acetaminophen	27	1.6	1.6
Irinotecan Hydrochloride	6	1.5	1.5
Ifosfamide	10	1.5	1.5
Dalfampridine	33	1.5	1.5
Linaclotide	12	1.5	1.5
Pazopanib Hydrochloride	12	1.4	1.4
Dimethyl Fumarate	53	1.4	1.4
Lacosamide	16	1.4	1.4
Cariprazine	4	1.4	1.4
Naproxen Sodium Tablet	22	1.3	1.3
Hydrocodone Bitartrate	18	1.3	1.3
Vortioxetine	7	1.3	1.3
Pegaspargase	5	1.3	1.3
Encorafenib	4	1.3	1.3
Ocrelizumab	25	1.3	1.3
Varenicline Tartrate	32	1.3	1.3
Teriparatide	45	1.3	1.3
Dronedarone	4	1.3	1.3
Blinatumomab	4	1.2	1.2
Cetuximab	12	1.2	1.2
Fingolimod Hcl	33	1.2	1.2
Loratadine And Pseudoephedrine Sulfate	3	1.2	1.2
Diclofenac Potassium	4	1.2	1.2
Ravulizumab	5	1.2	1.2
Abiraterone Acetate	15	1.2	1.2
Methoxy Polyethylene Glycol-Epoetin Beta	4	1.2	1.2
Axitinib	7	1.2	1.2
Diclofenac Potassium, Film Coated	3	1.2	1.2
Diclofenac Potassium Tablets	3	1.2	1.2
Alpelisib	3	1.1	1.1
Cannabidiol	8	1.1	1.1
Esketamine Hydrochloride	6	1.1	1.1
Vemurafenib	4	1.1	1.1
Avapritinib	4	1.1	1.1
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	10	1.0	1.0
Abiraterone	4	1.0	1.0
Treprostinil	36	0.9	0.9
Glatiramer Acetate	17	0.9	0.9
Ledipasvir And Sofosbuvir	5	0.8	0.8
Enzalutamide	15	0.8	0.8
Pirfenidone	10	0.8	0.8
Elexacaftor, Tezacaftor, And Ivacaftor	3	0.8	0.8
Ambrisentan	30	0.8	0.8
Nirmatrelvir And Ritonavir	10	0.6	0.6
Ranitidine Hydrochloride	10	0.6	0.6
Pomalidomide	17	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.