Reaction

Bone Lesion reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,562 reports · 198 co-occurring drugs

As of the last recalculation, Bone Lesion appears in 3,562 FAERS reports alongside 198 co-occurring drug terms. The strongest observed disproportionality signal is RIBOCICLIB (PRR 52.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ribociclib	262	52.3	52.7
Fulvestrant	254	48.3	48.7
Exemestane	137	38.8	39.1
Goserelin	87	38.8	39.0
Zoledronic Acid	236	36.7	36.9
Chlorhexidine Gluconate	56	36.4	36.6
Letrozole	341	35.7	35.9
Letrozole Tablets	233	30.2	30.4
Thalidomide	163	27.1	27.3
Everolimus Tablets	70	24.9	25.0
Anastrozole	148	24.5	24.6
Bicalutamide	62	24.2	24.3
Anastrozole Tablets	84	23.4	23.5
Melphalan	81	21.3	21.3
Melphalan Hydrochloride	87	20.8	20.8
Alpelisib	23	15.5	15.6
Daratumumab	100	15.0	15.1
Alendronate Sodium	238	14.7	14.7
Bortezomib	206	14.2	14.3
Everolimus	116	13.7	13.8
Cimetidine	21	12.8	12.8
Clindamycin Phosphate	71	12.7	12.7
Carfilzomib	60	12.6	12.6
Clindamycin	60	12.5	12.6
Meperidine Hydrochloride	19	12.1	12.1
Desoximetasone	39	12.1	12.1
Docusate Sodium - Sennosides	63	11.6	11.6
Capecitabine	160	10.6	10.7
Standardized Senna Concentrate	21	9.8	9.8
Dexamethasone 1.5 Mg	427	9.5	9.6
Abiraterone	22	9.5	9.5
Dexamethasone	427	9.4	9.4
Trastuzumab	102	8.9	8.9
Docusate Sodium	84	8.7	8.7
Ixazomib	41	8.4	8.4
Docetaxel Anhydrous	94	8.3	8.4
Docetaxel	94	8.3	8.4
Ado-Trastuzumab Emtansine	12	8.3	8.4
Amoxicillin And Clavulanate Potassium	38	8.2	8.3
Cephalexin	30	8.2	8.2
Ibuprofen And Diphenhydramine Citrate	32	8.1	8.1
Ampicillin	11	7.8	7.8
Ampicillin Sodium	11	7.8	7.8
Erythropoietin	27	7.7	7.7
Diphenoxylate Hydrochloride And Atropine Sulfate	18	7.7	7.7
Octreotide Acetate	39	7.5	7.5
Pomalidomide	128	7.5	7.5
Epoetin Alfa	15	7.4	7.4
Lapatinib	19	7.2	7.2
Acyclovir	135	7.1	7.1
Abiraterone Acetate	49	7.0	7.0
Prochlorperazine	33	7.0	7.0
Magnesium Hydroxide	16	7.0	7.0
Doxorubicin Hydrochloride	38	6.9	6.9
Enzalutamide	67	6.8	6.8
Filgrastim	43	6.7	6.8
Palbociclib	106	6.7	6.7
Lenalidomide	430	6.6	6.6
Terazosin Hydrochloride	10	6.6	6.6
Psyllium Husk	11	6.5	6.5
Gefitinib	10	6.5	6.5
Senna Leaf	25	6.4	6.4
Ketoconazole Foam	16	6.3	6.4
Bisacodyl Suppositories	14	6.3	6.3
Amlodipine Besylate And Benazepril Hydrochloride	10	6.3	6.3
Ketoconazole Cream, 2%	16	6.3	6.3
Naproxen	83	6.3	6.3
Biscodyl	14	6.3	6.3
Temazepam	40	6.3	6.3
Bisacodyl	15	6.2	6.3
Blinatumomab	11	6.2	6.2
Sennosides 8.6 Mg Tablets	22	6.2	6.2
Quinine	9	6.1	6.2
Senna	22	6.1	6.1
Ketoconazole	18	6.1	6.1
Risedronate Sodium	32	6.1	6.1
Nystatin Ointment	27	6.1	6.1
Nystatin Cream	27	6.0	6.1
Magnesium Sulfate In Water For	13	6.0	6.0
Morphine	74	5.9	5.9
Tolterodine Tartrate	9	5.9	5.9
Oxycodone Hydrochloride And Acetaminophen	97	5.9	5.9
Magnesium Sulfate Heptahydrate	13	5.8	5.9
Fluconazole	69	5.8	5.9
Magnesium Sulfate	13	5.8	5.8
Nystatin	27	5.8	5.8
Paclitaxel	96	5.8	5.8
Zolpidem Tartrate	129	5.7	5.8
Prochlorperazine Maleate	9	5.7	5.7
Darbepoetin Alfa	52	5.7	5.7
Promethazine Hydrochloride	18	5.7	5.7
Enoxaparin Sodium	55	5.7	5.7
Pazopanib Hydrochloride	26	5.6	5.7
Pertuzumab	26	5.6	5.6
Lorazepam	166	5.6	5.6
Paclitaxel (Aibumin-Bound)	77	5.6	5.6
Amoxicillin	71	5.5	5.5
Cabozantinib	44	5.4	5.4
Docusate Sodium 100Mg	22	5.4	5.4
Alendronate Sodium Tablet	17	5.4	5.4
Calcium	132	5.4	5.4
Dicyclomine Hydrochloride	13	5.3	5.4
Cyclophosphamide Injection, Solution	154	5.3	5.3
Cyclophosphamide	154	5.3	5.3
Cyclophosphamide For Injection	154	5.3	5.3
Vitamin E	28	5.2	5.2
Raloxifene Hydrochloride	13	5.2	5.2
Doxorubicin	77	5.1	5.1
Denosumab	171	5.1	5.1
Dronabinol	7	5.1	5.1
Ciprofloxacin Hydrochloride And Hydrocortisone	18	5.1	5.1
Losartan Potassium And Hydrochlorothiazide	10	5.0	5.0
Sulfasalazine	66	5.0	5.0
Metronidazole	54	5.0	5.0
Sunitinib Malate	33	4.9	4.9
Pemetrexed	18	4.9	4.9
Gemcitabine	32	4.8	4.8
Sennosides	24	4.7	4.7
Fam-Trastuzumab Deruxtecan-Nxki	8	4.6	4.6
Sulfamethoxazole And Trimethoprim	66	4.6	4.6
Ezetimibe And Simvastatin	12	4.6	4.6
Dexamethasone Sodium Phosphate	8	4.6	4.6
Leflunomide	80	4.5	4.5
Cefazolin	7	4.5	4.5
Olaparib	16	4.5	4.5
Lutetium Lu 177 Vipivotide Tetraxetan	10	4.4	4.4
Dorzolamide Hydrochloride And Timolol Maleate	6	4.4	4.4
Leuprolide Acetate	58	4.4	4.4
Loratadine And Pseudoephedrine Sulfate	6	4.4	4.4
Hydromorphone Hydrochloride	68	4.4	4.4
Tramadol Hydrochloride	28	4.4	4.4
Cefazolin Sodium	9	4.4	4.4
Hydroxychloroquine Sulfate	67	4.4	4.4
Naproxen Sodium	104	4.4	4.4
Lubiprostone	7	4.3	4.3
Pemetrexed Disodium	28	4.3	4.3
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	36	4.2	4.2
Golimumab	61	4.2	4.2
Fentanyl	69	4.2	4.2
Famotidine	82	4.2	4.2
Eszopiclone	18	4.1	4.1
Busulfan	11	4.1	4.1
Osimertinib	22	4.0	4.0
Gemcitabine Hydrochloride	36	4.0	4.0
Loperamide Hydrochloride	30	3.9	3.9
Granisetron Hydrochloride	7	3.9	3.9
Oxycodone	122	3.9	3.9
Dabrafenib	14	3.9	3.9
Carboplatin	82	3.8	3.8
Methadone	27	3.7	3.7
Cefepime	9	3.7	3.7
Imatinib	11	3.7	3.7
Fondaparinux Sodium	5	3.6	3.6
Morphine Sulfate	72	3.5	3.5
Apalutamide	7	3.5	3.5
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	3.4	3.4
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	3.4	3.4
Trametinib	14	3.4	3.4
Tenofovir Disoproxil Fumarate Tablets	5	3.4	3.4
Sorafenib	12	3.4	3.4
Selinexor	5	3.4	3.4
Etoposide	41	3.3	3.3
Cefepime Hydrochloride	9	3.3	3.3
Fluticasone Propionate And Salmeterol	23	3.2	3.2
Conjugated Estrogens And Medroxyprogesterone Acetate	13	3.2	3.2
Ibuprofen Tablets, Coated	23	3.2	3.2
Oxycodone Hydrochloride	115	3.2	3.2
Bevacizumab	66	3.2	3.2
Ibuprofen Sodium	23	3.2	3.2
Polyethylene Glycol 3350	51	3.1	3.1
Febuxostat	9	3.1	3.1
Loratadine Tablet	28	3.1	3.1
Tobramycin Solution	6	2.9	2.9
Asfotase Alfa	5	2.9	2.9
Tobramycin Sulfate	6	2.8	2.8
Alteplase	7	2.7	2.7
Axitinib	9	2.7	2.7
Secukinumab	68	2.5	2.5
Timolol	5	2.4	2.4
Levodopa	5	2.4	2.4
Pembrolizumab	41	2.3	2.3
Venetoclax	23	2.2	2.2
Rucaparib	3	2.0	2.0
Fentanyl Citrate	6	2.0	2.0
Pegfilgrastim	33	2.0	2.0
Bendamustine Hydrochloride	4	2.0	2.0
Nivolumab	32	1.9	1.9
Daptomycin	3	1.9	1.9
Crizotinib	4	1.8	1.8
Polatuzumab Vedotin	3	1.8	1.8
Lifitegrast	5	1.8	1.8
Ipilimumab	13	1.8	1.8
Relugolix	7	1.7	1.7
Atezolizumab	11	1.7	1.7
Abemaciclib	5	1.5	1.5
Avapritinib	3	1.4	1.4
Hydrocodone Bitartrate	10	1.3	1.3
Cinacalcet Hydrochloride	6	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.