Reaction

Purulent Discharge reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,219 reports · 185 co-occurring drugs

As of the last recalculation, Purulent Discharge appears in 4,219 FAERS reports alongside 185 co-occurring drug terms. The strongest observed disproportionality signal is KETOPROFEN (PRR 24.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ketoprofen	65	24.8	24.9
Chlorhexidine Gluconate	35	19.0	19.1
Treprostinil	372	15.9	16.0
Amitriptyline Hydrochloride	54	15.4	15.4
Sildenafil Powder,	94	13.3	13.3
Dalteparin Sodium	25	11.7	11.7
Exemestane	50	11.6	11.7
Sildenafil	131	11.5	11.5
Zoledronic Acid	91	11.4	11.4
Macitentan	145	10.7	10.7
Bicalutamide	32	10.4	10.5
0Xygen	99	10.1	10.1
Oxygen	99	10.1	10.1
Risedronate Sodium	60	9.6	9.7
Lidocaine Hydrochloride	102	8.5	8.5
Goserelin	22	8.1	8.1
Cephalexin	35	8.0	8.0
Clonidine	80	7.8	7.8
Melphalan Hydrochloride	39	7.7	7.7
Melphalan	35	7.6	7.7
Epoprostenol	20	7.6	7.6
Diphenoxylate Hydrochloride And Atropine Sulfate	20	7.2	7.2
Amoxicillin And Clavulanate Potassium	39	7.1	7.1
Cefazolin	13	7.0	7.1
Clindamycin Phosphate	46	6.9	6.9
Clindamycin	39	6.8	6.8
Tadalafil	132	6.7	6.7
Letrozole	82	6.7	6.7
Thalidomide	49	6.6	6.7
Sildenafil Citrate	163	6.5	6.5
Infliximab-Dyyb	38	6.5	6.5
Meperidine Hydrochloride	12	6.4	6.4
Losartan Potassium And Hydrochlorothiazide	15	6.4	6.4
Anastrozole	47	6.4	6.4
Cefazolin Sodium	15	6.2	6.2
Riociguat	40	6.1	6.1
Daspone	12	6.1	6.1
Dapsone Gel, 5%	12	6.1	6.1
Itraconazole	14	5.9	5.9
Magnesium Hydroxide	16	5.9	5.9
Epoetin Alfa	14	5.8	5.9
Fulvestrant	38	5.7	5.7
Cimetidine	11	5.6	5.7
Alendronate Sodium	112	5.6	5.6
Terbinafine Hydrochloride	10	5.6	5.6
Dapsone	12	5.6	5.6
Isoniazid	18	5.5	5.5
Nemolizumab-Ilto	14	5.4	5.5
Mupirocin Calcium	15	5.4	5.4
Docusate Sodium - Sennosides	35	5.4	5.4
Alendronate Sodium Tablet	20	5.3	5.3
Pyrazinamide	10	5.3	5.3
Ciprofolxacin	74	5.2	5.2
Ciprofloxacin Tablets	74	5.2	5.2
Bumetanide	27	5.1	5.1
Gentamicin Sulfate	16	5.0	5.0
Ciprofloxacin	90	4.9	4.9
Adalimumab	614	4.8	4.8
Promethazine Hydrochloride	18	4.8	4.8
Lapatinib	15	4.8	4.8
Mupirocin	13	4.8	4.8
Docusate Sodium	55	4.7	4.8
Iron	63	4.7	4.7
Ciprofloxacin Hydrochloride	91	4.7	4.7
Ketoconazole Foam	14	4.7	4.7
Ketoconazole Cream, 2%	14	4.7	4.7
Sodium Chloride Tablet	68	4.6	4.6
Sodium Chloride Tablets	68	4.6	4.6
Selexipag	24	4.6	4.6
Erythropoietin	19	4.6	4.6
Docusate Sodium 100Mg	22	4.6	4.6
Sodium Chloride	72	4.6	4.6
Gentamicin	12	4.5	4.5
Nystatin Ointment	24	4.5	4.5
Nystatin Cream	24	4.5	4.5
Posaconazole Delayed-Release	10	4.5	4.5
Erythromycin	17	4.5	4.5
Cefepime	13	4.5	4.5
Metronidazole	57	4.4	4.5
Rifampicin	9	4.4	4.4
Ambrisentan	109	4.4	4.4
Nystatin	24	4.3	4.4
Hydrocortisone Acetate	63	4.3	4.3
Cefepime Hydrochloride	14	4.3	4.3
Azathioprine	75	4.3	4.3
Temazepam	32	4.2	4.2
Vancomycin	48	4.1	4.1
Fluconazole	58	4.1	4.1
Ciprofloxacin Hydrochloride And Hydrocortisone	17	4.0	4.0
Ketoconazole	14	4.0	4.0
Metolazone	9	4.0	4.0
Amphotericin B	10	3.9	3.9
Vancomycin Hydrochloride	52	3.9	3.9
Leflunomide	82	3.9	3.9
Potassium Chloride	89	3.9	3.9
Potassium Chloride, Dextrose Monohydrate	72	3.9	3.9
Potassium Chloride Oral	72	3.9	3.9
Potassium Chloride Extended-Release	72	3.9	3.9
Primidone	8	3.9	3.9
Gefitinib	7	3.8	3.8
Sennosides 8.6 Mg Tablets	16	3.8	3.8
Cetirizine Hcl	7	3.8	3.8
Hydroxyzine Hydrochloride	10	3.8	3.8
Hydroxyzine Hydrochloride Oral	10	3.8	3.8
Senna	16	3.8	3.8
Spironolactone	103	3.7	3.7
Metronidazole Topical	35	3.6	3.6
Buspirone Hydrochloride	8	3.6	3.6
Insulin	40	3.6	3.6
Piperacillin Sodium And Tazobactam Sodium	14	3.5	3.5
Doxyclycline Hyclate	12	3.5	3.5
Capecitabine	63	3.4	3.4
Filgrastim	26	3.4	3.4
Ibuprofen And Diphenhydramine Citrate	16	3.4	3.4
Loperamide Hydrochloride And Dimethicone	22	3.4	3.4
Meropenem	22	3.4	3.4
Tofacitinib Citrate	9	3.4	3.4
Raloxifene Hydrochloride	10	3.4	3.4
Desoximetasone	13	3.4	3.4
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	14	3.4	3.4
Naproxen Sodium, Pseudoephedrine Hydrochloride	14	3.4	3.4
Posaconazole	11	3.3	3.3
Linezolid	20	3.3	3.3
Sulfasalazine	52	3.3	3.3
Mycophenolic Acid	21	3.2	3.2
Daptomycin	6	3.2	3.2
Paricalcitol	9	3.1	3.1
Dorzolamide Hydrochloride And Timolol Maleate	5	3.1	3.1
Oxycodone Hydrochloride And Acetaminophen	61	3.1	3.1
Ribociclib	19	3.0	3.0
Amikacin	10	2.9	2.9
Prochlorperazine	16	2.9	2.9
Bosentan	29	2.9	2.9
Acetaminophen And Codeine	7	2.8	2.8
Nevirapine	5	2.7	2.7
Rifampin	8	2.7	2.7
Fluorouracil	42	2.7	2.7
Letrozole Tablets	26	2.7	2.7
Trastuzumab	37	2.7	2.7
Rivastigmine	10	2.6	2.6
Fluorouracil Cream, 0.5%	40	2.6	2.6
Bimekizumab	11	2.6	2.6
Erlotinib	5	2.5	2.5
Eszopiclone	13	2.5	2.5
Secukinumab	81	2.5	2.5
Etonogestrel	24	2.5	2.5
Methadone	21	2.4	2.4
Brentuximab Vedotin	5	2.4	2.4
Iohexol	4	2.4	2.4
Insulin Degludec	11	2.3	2.3
Alteplase	7	2.3	2.3
Methadone Hydrochloride	5	2.3	2.3
Doxorubicin Hydrochloride	15	2.3	2.3
Panitumumab	7	2.2	2.2
Hydromorphone Hydrochloride	40	2.2	2.2
Paclitaxel	43	2.2	2.2
Regorafenib	5	2.1	2.1
Lifitegrast	7	2.1	2.1
Tobramycin	10	2.1	2.1
Cetuximab	13	2.1	2.1
Fluticasone Propionate And Salmeterol	17	2.0	2.0
Cortisone Acetate	5	2.0	2.0
Erlotinib Hydrochloride	5	2.0	2.0
Risankizumab-Rzaa	32	1.9	1.9
Darbepoetin Alfa	21	1.9	1.9
Morphine Sulfate	47	1.9	1.9
Bortezomib	33	1.8	1.8
Glycerin, Lidocaine	5	1.8	1.8
Golimumab	30	1.7	1.7
Belimumab	11	1.7	1.7
Docosanol	5	1.7	1.7
Sarilumab	9	1.7	1.7
Bimatoprost	9	1.5	1.5
Etanercept	181	1.5	1.5
Pazopanib Hydrochloride	8	1.5	1.5
Aflibercept	9	1.4	1.4
Leuprolide Acetate	21	1.3	1.3
Pirfenidone	11	1.3	1.3
Cabozantinib	12	1.2	1.2
Palivizumab	3	1.0	1.0
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.8	0.8
Salicylic Acid	8	0.7	0.7
Levonorgestrel	26	0.6	0.6
Dupilumab	54	0.5	0.5
Adapalene	12	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.