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Which drugs are most reported with Papule?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,859 reports · 266 co-occurring drugs

As of the last recalculation, Papule appears in 6,859 FAERS reports alongside 266 co-occurring drug terms. The strongest observed disproportionality signal is IOHEXOL (PRR 14.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Iohexol	38	14.0	14.0
Ketoconazole Foam	61	12.6	12.7
Ketoconazole Cream, 2%	61	12.6	12.6
Ketoconazole	63	11.1	11.2
Clobetasol Propionate Ointment Usp, 0.05%	36	10.7	10.7
Terbinafine Hydrochloride	31	10.6	10.7
Clobetasol Propionate	35	10.3	10.3
Secukinumab	489	9.8	9.9
Mupirocin	37	8.4	8.4
Mometasone	50	8.3	8.3
Mupirocin Calcium	37	8.2	8.2
Omalizumab	218	8.0	8.0
Rifampicin	25	7.5	7.5
Triamcinolone Acetonide Ointment Usp, 0.05%	56	7.3	7.3
Panitumumab	36	7.0	7.0
Daspone	21	6.6	6.6
Dapsone Gel, 5%	21	6.6	6.6
Dapsone	23	6.6	6.6
Minocycline	25	6.5	6.5
Cetirizine Hydrochloride Allergy	64	6.5	6.5
Cetirizine Hydrochloride Tablets	64	6.5	6.5
Tretinoin	17	6.4	6.4
Desloratadine	22	6.2	6.3
Clindamycin Phosphate	66	6.0	6.1
Posaconazole Delayed-Release	21	5.8	5.8
Clindamycin	54	5.8	5.8
Triamcinolone Acetonide	57	5.6	5.6
Micafungin Sodium	15	5.4	5.4
Doxepin Hydrochloride	22	5.3	5.3
Isoniazid	27	5.1	5.1
Hydroxyzine	78	5.0	5.0
Anti-Itch	109	5.0	5.0
Anti-Pruritic	109	5.0	5.0
Antipruritic (Anti-Itch)	109	5.0	5.0
Cool Relief Gel With Aloe	109	5.0	5.0
Drs. Hydrocortisone	109	5.0	5.0
Hydrocortisone Continuous Spray	109	5.0	5.0
Hydrocortisone Spray	109	5.0	5.0
Anti-Itch Cream	109	5.0	5.0
Hydrocortisone Lotion	109	5.0	5.0
Hydrocortisone Cream 1%	109	5.0	5.0
Hydrocortisone Cream 1/2%	109	5.0	5.0
Hydrocortisone 1%	109	5.0	5.0
Hydrocortisone Cream	109	5.0	5.0
Carbamazepine	107	4.9	4.9
Hydrocortisone Acetate	110	4.7	4.7
Pyrazinamide	14	4.5	4.5
Atovaquone	12	4.5	4.5
Hydrocortisone	131	4.5	4.5
Cetirizine	114	4.5	4.5
Isotretinoin	73	4.5	4.5
Tranexamic Acid	13	4.4	4.4
Risankizumab-Rzaa	117	4.4	4.4
Chlorhexidine Gluconate	13	4.3	4.3
Doxycycline	96	4.3	4.3
Piperacillin And Tazobactam	18	4.3	4.3
Doxycycline Hyclate	94	4.3	4.3
Infliximab-Dyyb	40	4.2	4.2
Posaconazole	22	4.1	4.1
Cefazolin Sodium	16	4.0	4.0
Clotrimazole	16	4.0	4.0
Drs. Clotrimazole	15	3.9	3.9
Family Wellness Clotrimazole	15	3.9	3.9
Clotrimazole Topical	15	3.9	3.9
Tacrolimus Ointment 0.1%	156	3.9	3.9
Tacrolimus Extended-Release Capsules	156	3.9	3.9
Sodium Chloride	99	3.8	3.8
Desoximetasone	24	3.8	3.8
Crisaborole	12	3.8	3.8
Cetiirizine	52	3.7	3.8
Lamotirigine	86	3.7	3.7
Lamotrigine Extended-Release	86	3.7	3.7
Lamotrigine Chewable Dispersible	86	3.7	3.7
Cefazolin	11	3.7	3.7
Cephalexin	26	3.7	3.7
Lamotrigine	155	3.6	3.6
Doxepin	12	3.6	3.6
Sodium Chloride Tablet	85	3.5	3.5
Sodium Chloride Tablets	85	3.5	3.5
Basiliximab	13	3.4	3.4
Upadacitinib	88	3.3	3.3
Montelukast	89	3.2	3.2
Tofacitinib Citrate	14	3.2	3.2
Azithromycin Dihydrate	61	3.2	3.2
Tacrolimus	161	3.2	3.2
Tenofovir Disoproxil Fumarate Tablets	9	3.2	3.2
Vancomycin	59	3.1	3.1
Piperacillin Sodium And Tazobactam Sodium	20	3.1	3.1
Piperacillin Sodium,Tazobactam Sodium	27	3.1	3.1
Nevirapine	9	3.0	3.0
Oxcarbazepine	32	3.0	3.0
Dexamethasone Sodium Phosphate	10	3.0	3.0
Indomethacin	13	3.0	3.0
Pegvaliase-Pqpz	8	3.0	3.0
Botulinum Toxin Type A	12	2.9	2.9
Esomeprazole Magnesium Capsule, Delayed Release	14	2.9	2.9
Esomeprazole Magnesium Delayed Release Capsules	14	2.9	2.9
Esomeprazole Magnesium Dihydrate	14	2.9	2.9
Loratadine Oral	47	2.9	2.9
Nystatin Ointment	25	2.9	2.9
Everolimus Tablets	16	2.9	2.9
Nystatin Cream	25	2.9	2.9
Niraparib	21	2.9	2.9
Vancomycin Hydrochloride	62	2.9	2.9
Minoxidil Foam 5% (Womens)	31	2.9	2.9
Trimethoprim	11	2.8	2.8
Cetirizine Hydrochloride	151	2.8	2.8
Cyclosporine	102	2.8	2.8
Canakinumab	10	2.8	2.8
Nystatin	25	2.8	2.8
Hydroxyzine Hydrochloride	12	2.8	2.8
Hydroxyzine Hydrochloride Oral	12	2.8	2.8
Lamivudine Oral	23	2.8	2.8
Meropenem	29	2.7	2.8
Diphenhydramine Hydrochloride	148	2.7	2.7
Azithromycin	36	2.7	2.7
Gentamicin Sulfate	14	2.7	2.7
Pitavastatin Calcium	9	2.7	2.7
Ganciclovir	9	2.7	2.7
Amoxicillin	66	2.6	2.6
Anti-Thymocyte Globulin (Rabbit)	7	2.6	2.6
Azithromycin Monohydrate	36	2.6	2.6
Lidocaine Hydrochloride And Epinephrine Bitartrate	46	2.6	2.6
Lidicaine	42	2.6	2.6
Burn Relief	42	2.6	2.6
Lidocaine Hydrochloride And Epinephrine	42	2.6	2.6
Mycophenolate Mofetil	115	2.6	2.6
Mycophenolate Mofetil Hydrochloride	115	2.6	2.6
Adalimumab	572	2.6	2.6
Ganciclovir Sodium	9	2.6	2.6
Lidocaine, Menthol	42	2.6	2.6
Adalimumab-Aaty	40	2.6	2.6
Clarithromycin	29	2.6	2.6
Gentamicin	11	2.6	2.6
Vemurafenib	10	2.5	2.5
Cetuximab	26	2.5	2.5
Doxyclycline Hyclate	14	2.5	2.5
Adalimumab-Fkjp	38	2.5	2.5
Lidocaine Hydrochloride	49	2.5	2.5
Montelukast Sodium	98	2.5	2.5
Lamivudine	25	2.5	2.5
Methotrexate	329	2.4	2.4
Febuxostat Tablets 40 Mg	8	2.4	2.4
Febuxostat Tablets 80 Mg	8	2.4	2.4
Cyclobenzaprine Hydrochloride	7	2.4	2.4
Lidocaine 4%	42	2.3	2.3
Valacyclovir	32	2.3	2.3
Fingolimod Hcl	66	2.3	2.3
Levofloxacin	46	2.3	2.3
Levofloxacin In 5% Dextrose	46	2.3	2.3
Ceftriaxone	25	2.3	2.3
Dextrose	10	2.3	2.3
Acyclovir	86	2.3	2.3
Fexofenadine Hcl	7	2.3	2.3
Methotrexate Sodium	354	2.3	2.3
Dextrose Monohydrate	10	2.3	2.3
Anastrozole Tablets	16	2.3	2.3
Cholestyramine	9	2.3	2.3
Cabotegravir	6	2.3	2.3
Sirolimus	10	2.3	2.3
Adalimumab-Adaz	39	2.2	2.3
Linezolid	22	2.2	2.2
Prednisolone	132	2.2	2.2
Prednisolone Oral	132	2.2	2.2
Prednisolone Oral Solution	132	2.2	2.2
Azelastine	13	2.2	2.2
Ursosiol	14	2.2	2.2
Abacavir Sulfate	7	2.2	2.2
Efavirenz	8	2.2	2.2
Loratadine	76	2.2	2.2
Everolimus	36	2.2	2.2
Nemolizumab-Ilto	9	2.2	2.2
Levocetirizine Dihydrochloride	17	2.1	2.2
Fenofibrate	25	2.1	2.1
Ceftriaxone Sodium	27	2.1	2.1
Trametinib	17	2.1	2.1
Irinotecan Hydrochloride	9	2.1	2.1
Zoledronic Acid	28	2.1	2.1
Minoxidil	31	2.1	2.1
Ursodiol	15	2.1	2.1
Loperamide Hydrochloride Oral	7	2.1	2.1
Nilotinib	20	2.1	2.1
Tizanidine	16	2.0	2.0
Nicotine Polacrilex Mini	10	2.0	2.0
Nicotine Polarilex	10	2.0	2.0
Tobramycin Solution	8	2.0	2.0
Amlodipine	177	2.0	2.0
Dabrafenib	14	2.0	2.0
Avapritinib	8	2.0	2.0
Finasteride	39	2.0	2.0
Tobramycin Sulfate	8	2.0	2.0
Mepolizumab	32	2.0	2.0
Mesalamine	36	2.0	2.0
Losartan	111	1.9	1.9
Amlodipine Besylate And Valsartan	7	1.9	1.9
Oseltamivir	5	1.9	1.9
Ethyl Alcohol	17	1.9	1.9
Cytarabine	37	1.9	1.9
Dutasteride	5	1.9	1.9
Valacyclovir Hydrochloride	43	1.9	1.9
Salicylic Acid	32	1.8	1.8
Febuxostat	10	1.8	1.8
Apremilast	84	1.8	1.8
Miconazole Nitrate	5	1.7	1.7
Ibrutinib	46	1.7	1.7
Imatinib	10	1.7	1.7
Loratadine Tablet	30	1.7	1.7
Erlotinib Hydrochloride	7	1.7	1.7
Fesoterodine Fumarate	6	1.7	1.7
Rifampin	8	1.7	1.7
Etanercept	321	1.7	1.7
Fluorouracil	42	1.7	1.7
Dapagliflozin	17	1.6	1.6
Fremanezumab-Vfrm	6	1.6	1.6
Lenalidomide	218	1.6	1.6
Baricitinib	5	1.6	1.6
Denosumab	104	1.6	1.6
Erlotinib	5	1.6	1.6
Isopropyl Alcohol	17	1.5	1.5
Inclisiran	4	1.5	1.5
Fluorouracil Cream, 0.5%	37	1.5	1.5
Dofetilide	5	1.4	1.4
Bimekizumab	10	1.4	1.4
Alpelisib	4	1.4	1.4
Adapalene	83	1.4	1.4
Evolocumab	72	1.4	1.4
Onabotulinumtoxina	34	1.3	1.3
Alcohol	17	1.3	1.3
Bortezomib	39	1.3	1.3
Ribavirin	28	1.3	1.3
Daptomycin	4	1.3	1.3
Insulin Degludec	10	1.3	1.3
Nivolumab	41	1.3	1.3
Ofatumumab	14	1.3	1.3
Tobramycin	10	1.3	1.3
Acalabrutinib	5	1.3	1.3
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	1.2	1.2
Ipilimumab	17	1.2	1.2
Prasugrel Hydrochloride	4	1.2	1.2
Pomalidomide	40	1.2	1.2
Blinatumomab	4	1.2	1.2
Ixekizumab	14	1.1	1.1
Pemetrexed	8	1.1	1.1
Ustekinumab	37	1.1	1.1
Dupilumab	172	1.1	1.1
Sulfur	3	1.1	1.1
Pembrolizumab	37	1.1	1.1
Ixazomib	10	1.1	1.1
Abaloparatide	10	1.0	1.0
Acetaminophen, Aspirin, And Caffeine	7	1.0	1.0
Daratumumab	13	1.0	1.0
Suvorexant	4	0.9	0.9
Eltrombopag Olamine	7	0.9	0.9
Romosozumab-Aqqg	4	0.9	0.9
Cabozantinib	14	0.9	0.9
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	9	0.9	0.9
Apalutamide	3	0.8	0.8
Erenumab-Aooe	14	0.8	0.8
Durvalumab	5	0.7	0.7
Palivizumab	3	0.6	0.6
Ranitidine Hydrochloride	10	0.6	0.6
Relugolix	4	0.5	0.5
Galcanezumab-Gnlm	5	0.5	0.5
Cinacalcet Hydrochloride	6	0.4	0.4
Etonogestrel	6	0.4	0.4
Copper	4	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.