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Which drugs are most reported with Gastrointestinal inflammation?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,679 reports · 230 co-occurring drugs

As of the last recalculation, Gastrointestinal Inflammation appears in 7,679 FAERS reports alongside 230 co-occurring drug terms. The strongest observed disproportionality signal is VEDOLIZUMAB (PRR 21.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Vedolizumab	630	21.5	21.7
Mesalamine	299	15.0	15.1
Adalimumab	2,619	14.7	14.8
Melphalan	112	13.5	13.6
Melphalan Hydrochloride	118	12.9	13.0
Azathioprine	387	12.5	12.5
Thiotepa	36	10.3	10.3
Infliximab-Dyyb	105	9.9	9.9
Teduglutide	36	7.3	7.3
Risankizumab-Rzaa	213	7.2	7.3
Infliximab	536	7.1	7.1
Cholestyramine	31	7.0	7.0
Mercaptopurine	42	6.6	6.6
Iron	154	6.4	6.4
Dicyclomine Hydrochloride	32	6.1	6.1
Ciprofloxacin Hydrochloride And Hydrocortisone	44	5.8	5.8
Anti-Thymocyte Globulin (Rabbit)	17	5.7	5.7
Hyoscyamine Sulfate	19	5.6	5.6
Dimenhydrinate	22	5.6	5.6
Busulfan	31	5.4	5.4
Adalimumab-Adaz	103	5.3	5.4
Ustekinumab	193	5.2	5.2
Metronidazole	118	5.1	5.1
Meperidine Hydrochloride	17	5.0	5.0
Diphenoxylate Hydrochloride And Atropine Sulfate	25	5.0	5.0
Hydrocortisone	157	4.8	4.9
Adalimumab-Aaty	83	4.8	4.8
Budesonide	102	4.7	4.7
Adalimumab-Fkjp	79	4.7	4.7
Sirolimus	23	4.6	4.6
Thalidomide	61	4.5	4.5
Etoposide	119	4.4	4.4
Cytarabine	95	4.3	4.3
Upadacitinib	122	4.1	4.1
Metronidazole Topical	71	4.1	4.1
Ursosiol	29	4.1	4.1
Ciprofloxacin Hydrochloride	138	3.9	3.9
Ciprofloxacin	130	3.9	3.9
Octreotide Acetate	42	3.7	3.7
Ganciclovir	14	3.7	3.7
Prednisone	634	3.6	3.6
Ursodiol	29	3.6	3.6
Ganciclovir Sodium	14	3.6	3.6
Loperamide Hydrochloride And Dimethicone	42	3.6	3.6
Calcium	185	3.4	3.4
Capecitabine	113	3.4	3.4
Candesartan	44	3.4	3.4
Psyllium Husk	12	3.3	3.3
Human Immunoglobulin G	25	3.3	3.3
Ciprofolxacin	86	3.3	3.3
Ciprofloxacin Tablets	86	3.3	3.3
Desloratadine	12	3.0	3.0
Methotrexate	445	3.0	3.0
Fludarabine Phosphate	43	3.0	3.0
Hydrocortisone Sodium Succinate	10	2.9	2.9
Loperamide Hydrochloride	47	2.9	2.9
Hydrocortisone Acetate	76	2.9	2.9
Methotrexate Sodium	484	2.8	2.8
Itraconazole	12	2.8	2.8
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	31	2.8	2.8
Pantoprazole Sodium In 0.9% Sodium Chloride	63	2.8	2.8
Pantoprazole Sodium Injection	63	2.8	2.8
Pantoprazole	247	2.7	2.7
Cisplatin	77	2.7	2.7
Zinc	24	2.6	2.6
Anti-Itch	65	2.6	2.6
Anti-Pruritic	65	2.6	2.6
Antipruritic (Anti-Itch)	65	2.6	2.6
Cool Relief Gel With Aloe	65	2.6	2.6
Drs. Hydrocortisone	65	2.6	2.6
Hydrocortisone Continuous Spray	65	2.6	2.6
Hydrocortisone Spray	65	2.6	2.6
Anti-Itch Cream	65	2.6	2.6
Hydrocortisone Lotion	65	2.6	2.6
Hydrocortisone Cream 1%	65	2.6	2.6
Hydrocortisone Cream 1/2%	65	2.6	2.6
Hydrocortisone 1%	65	2.6	2.6
Hydrocortisone Cream	65	2.6	2.6
Zinc Chloride	24	2.6	2.6
Bortezomib	86	2.6	2.6
Folic Acid	231	2.6	2.6
Diphenhydramine	59	2.5	2.5
Midazolam Hydrochloride	25	2.5	2.5
Bisacodyl Suppositories	12	2.5	2.5
Vincristine Sulfate	27	2.5	2.5
Biscodyl	12	2.5	2.5
Zinc Gluconate	24	2.5	2.5
Posaconazole Delayed-Release	10	2.5	2.5
Cyclophosphamide Injection, Solution	159	2.5	2.5
Cyclophosphamide	159	2.5	2.5
Cyclophosphamide For Injection	159	2.5	2.5
Methimazole	7	2.4	2.4
Pancrelipase	34	2.4	2.4
Brentuximab Vedotin	9	2.4	2.4
Dronabinol	7	2.4	2.4
Dexlansoprazole	36	2.3	2.3
Magnesium	70	2.3	2.3
Ergocalciferol	321	2.3	2.3
Bisacodyl	12	2.3	2.3
Sucralfate Oral	12	2.3	2.3
Sucralfate Oral Suspension	12	2.3	2.3
Indapamide	15	2.3	2.3
Ferrous Sulfate	41	2.2	2.2
Buspirone Hydrochloride	9	2.2	2.2
Alendronate Sodium Tablet	15	2.2	2.2
Instalax Polyethylene Glycol 3350	10	2.2	2.2
Sucralfate	19	2.2	2.2
Pemetrexed	17	2.2	2.2
Nitrofurantoin	13	2.1	2.1
Polyethylene Glycol 400	10	2.1	2.1
Piperacillin And Tazobactam	10	2.1	2.1
Olmesartan Medoxomil	28	2.1	2.1
Naproxen	61	2.1	2.1
Nitrofurantoin (Monohydrate/Macrocrystals)	13	2.1	2.1
Vitamin C	71	2.1	2.1
Chlorthalidone	9	2.1	2.1
Tofacitinib Citrate	10	2.1	2.1
Hydroxyzine Hydrochloride	10	2.1	2.1
Hydroxyzine Hydrochloride Oral	10	2.1	2.1
Goserelin	10	2.0	2.0
Pantoprazole Sodium	109	2.0	2.0
Daspone	7	1.9	1.9
Dapsone Gel, 5%	7	1.9	1.9
Midazolam	18	1.9	1.9
Fluorouracil	55	1.9	1.9
Fluorouracil Cream, 0.5%	54	1.9	1.9
Micafungin Sodium	6	1.9	1.9
Golimumab	60	1.9	1.9
Multivitamin	35	1.9	1.9
Oxaliplatin	51	1.9	1.9
Liothyronine Sodium	6	1.9	1.9
Imatinib	12	1.8	1.8
Posaconazole	11	1.8	1.8
Certolizumab Pegol	79	1.8	1.8
Doxorubicin Hydrochloride	22	1.8	1.8
Sumatriptan Succinate	17	1.8	1.8
Granisetron Hydrochloride	7	1.8	1.8
Omeprazole	228	1.8	1.8
Valsartan And Hydrochlorothiazide	9	1.8	1.8
Dapsone	7	1.8	1.8
Sulfasalazine	51	1.8	1.8
Pegaspargase	8	1.8	1.8
Nilotinib	19	1.7	1.7
Piperacillin Sodium,Tazobactam Sodium	17	1.7	1.7
Lanreotide Acetate	5	1.7	1.7
Quinapril Hydrochloride	5	1.7	1.7
Omeprazole Magnesium	277	1.7	1.7
Tizanidine	15	1.7	1.7
Metoclopramide	34	1.7	1.7
Dexamethasone 1.5 Mg	179	1.7	1.7
Filgrastim	23	1.7	1.7
Peginterferon Beta-1A	8	1.7	1.7
Secukinumab	98	1.7	1.7
Dexamethasone	179	1.7	1.7
Ribociclib	19	1.6	1.6
Linaclotide	16	1.6	1.6
Umeclidinium Bromide And Vilanterol Trifenatate	10	1.6	1.6
Fish Oil	54	1.6	1.6
Lenvatinib	19	1.6	1.6
Cortisone Acetate	7	1.5	1.5
Ifosfamide	12	1.5	1.5
Umeclidinium	5	1.5	1.5
Pemetrexed Disodium	21	1.5	1.5
Abemaciclib	11	1.5	1.5
Amlodipine Besylate And Valsartan	6	1.5	1.5
Carfilzomib	15	1.4	1.4
Doxorubicin	46	1.4	1.4
Dasatinib	19	1.4	1.4
Fexofenadine Hydrochloride	11	1.4	1.4
Diroximel Fumarate	6	1.4	1.4
Niraparib	11	1.3	1.3
Riociguat	16	1.3	1.3
Bevacizumab	60	1.3	1.3
Ozanimod Hydrochloride	4	1.3	1.3
Sorafenib	10	1.3	1.3
Rifaximin	10	1.3	1.3
Granisetron	5	1.3	1.3
Desoximetasone	9	1.3	1.3
Pembrolizumab	49	1.3	1.3
Canakinumab	5	1.3	1.3
Fesoterodine Fumarate	5	1.3	1.3
Alpelisib	4	1.2	1.2
Levocetirizine Dihydrochloride	11	1.2	1.2
Gemcitabine	18	1.2	1.2
Bendamustine Hcl	7	1.2	1.2
Panitumumab	7	1.2	1.2
Nintedanib	14	1.2	1.2
Sevelamer Carbonate	5	1.2	1.2
Hydromorphone Hydrochloride	39	1.1	1.1
Rimegepant Sulfate	5	1.1	1.1
Dronedarone	4	1.1	1.1
Fentanyl Citrate	7	1.1	1.1
Irinotecan Hydrochloride	5	1.1	1.1
Tofacitinib	71	1.0	1.0
Inclisiran	3	1.0	1.0
Glecaprevir And Pibrentasvir	4	1.0	1.0
Axitinib	7	1.0	1.0
Paricalcitol	5	1.0	1.0
Asenapine Maleate	3	0.9	0.9
Voclosporin	3	0.9	0.9
Docetaxel Anhydrous	23	0.9	0.9
Docetaxel	23	0.9	0.9
Rucaparib	3	0.9	0.9
Trametinib	8	0.9	0.9
Avapritinib	4	0.9	0.9
Oral Semaglutide	24	0.9	0.9
Palivizumab	5	0.9	0.9
Ixekizumab	12	0.9	0.9
Nivolumab	31	0.9	0.9
Brexpiprazole	5	0.8	0.8
Ipilimumab	13	0.8	0.8
Daratumumab	12	0.8	0.8
Patiromer	4	0.8	0.8
Teriflunomide	13	0.8	0.8
Trifluridine And Tipiracil	3	0.8	0.8
Cabozantinib	13	0.7	0.7
Isotretinoin	13	0.7	0.7
Fremanezumab-Vfrm	3	0.7	0.7
Guselkumab	9	0.7	0.7
Durvalumab	5	0.7	0.7
Olaparib	5	0.6	0.6
Tirzepatide	38	0.6	0.6
Romosozumab-Aqqg	3	0.6	0.6
Apremilast	30	0.6	0.6
Dulaglutide	18	0.5	0.5
Pegfilgrastim	20	0.5	0.5
Evolocumab	31	0.5	0.5
Bimekizumab	4	0.5	0.5
Lifitegrast	3	0.5	0.5
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	4	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.